RegulonDB RegulonDB 10.9: Gene Form
   

aat gene in Escherichia coli K-12 genome


Gene local context to scale (view description)

cydC aat infA terminator TSS_1057 TSS_1057 aatp5 aatp5 infAp1 infAp1 infAp2 infAp2 TSS_1056 TSS_1056 TSS_1055 TSS_1055

Gene      
Name: aat    Texpresso search in the literature
Synonym(s): ECK0876, EG11112, b0885, ycaA
Genome position(nucleotides): 926728 <-- 927432 Genome Browser
Strand: reverse
Sequence: Get nucleotide sequence FastaFormat
GC content %:  
54.04
External database links:  
ASAP:
ABE-0003009
ECHOBASE:
EB1103
ECOLIHUB:
aat
OU-MICROARRAY:
b0885
STRING:
511145.b0885
COLOMBOS: aat


Product      
Name: leucyl/phenylalanyl-tRNA—protein transferase
Synonym(s): Aat, YcaA, leucyl, phenylalanyl-tRNA-protein transferase
Sequence: Get amino acid sequence Fasta Format
Cellular location: cytosol
Molecular weight: 26.618
Isoelectric point: 7.249
Motif(s):
 
Type Positions Sequence
35 -> 203 PARLLMAYQRGIFPWFSPGDPILWWSPDPRAVLWPESLHISRSMKRFHKRSPYRVTMNYAFGQVIEGCASDREEGTWITRGVVEAYHRLHELGHAHSIEVWREDELVGGMYGVAQGTLFCGESMFSRMENASKTALLVFCEEFIGHGGKLIDCQVLNDHTASLGACEIP

 

Classification:
Multifun Terms (GenProtEC)  
  1 - metabolism --> 1.2 - degradation of macromolecules --> 1.2.3 - proteins/peptides/glycopeptides
  2 - information transfer --> 2.3 - protein related --> 2.3.6 - turnover, degradation
Gene Ontology Terms (GO)  
cellular_component GO:0005737 - cytoplasm
GO:0005829 - cytosol
molecular_function GO:0016740 - transferase activity
GO:0016746 - transferase activity, transferring acyl groups
GO:0016755 - transferase activity, transferring amino-acyl groups
GO:0008914 - leucyltransferase activity
biological_process GO:0030163 - protein catabolic process
Note(s): Note(s): ...[more].
External database links:  
DIP:
DIP-48235N
ECOCYC:
EG11112-MONOMER
ECOLIWIKI:
b0885
INTERPRO:
IPR004616
INTERPRO:
IPR016181
INTERPRO:
IPR042203
PANTHER:
PTHR30098
PDB:
2Z3O
PDB:
2Z3P
PDB:
2CXA
PDB:
2DPS
PDB:
2DPT
PDB:
2Z3K
PDB:
2Z3L
PDB:
2Z3M
PDB:
2Z3N
PFAM:
PF03588
PRIDE:
P0A8P1
PRODB:
PRO_000022026
REFSEQ:
NP_415405
SMR:
P0A8P1
UNIPROT:
P0A8P1


Operon      
Name: aat         
Operon arrangement:
Transcription unit        Promoter
aat


Elements in the selected gene context region unrelated to any object in RegulonDB      

  Type Name Post Left Post Right Strand Notes Evidence (Confirmed, Strong, Weak) References
  promoter TSS_1055 926361 reverse nd [RS-EPT-CBR] [1]
  promoter TSS_1056 926419 reverse nd [RS-EPT-CBR] [1]
  promoter aatp5 927460 reverse Similarity to the consensus
Read more >
[ICWHO] [2]
  promoter TSS_1057 928505 reverse nd [RS-EPT-CBR] [1]


Evidence    

 [RS-EPT-CBR] RNA-seq using two enrichment strategies for primary transcripts and consistent biological replicates

 [ICWHO] Inferred computationally without human oversight



Reference(s)    

 [1] Salgado H, Peralta-Gil M, Gama-Castro S, Santos-Zavaleta A, Muñiz-Rascado L, García-Sotelo JS, Weiss V, Solano-Lira H, Martínez-Flores I, Medina-Rivera A, Salgado-Osorio G, Alquicira-Hernández S, Alquicira-Hernández K, López-Fuentes A, Porrón-Sotelo L, Huerta AM, Bonavides-Martínez C, Balderas-Martínez YI, Pannier L, Olvera M, Labastida A, Jiménez-Jacinto V, Vega-Alvarado L, Del Moral-Chávez V, Hernández-Alvarez A, Morett E, Collado-Vides J., 2012, RegulonDB v8.0: omics data sets, evolutionary conservation, regulatory phrases, cross-validated gold standards and more., Nucleic Acids Res.

 [2] Huerta AM., Collado-Vides J., 2003, Sigma70 promoters in Escherichia coli: specific transcription in dense regions of overlapping promoter-like signals., J Mol Biol 333(2):261-78


RegulonDB