RegulonDB RegulonDB 10.9: Gene Form
   

mdtQ gene in Escherichia coli K-12 genome


Gene local context to scale (view description)

mdtQ yohF yohP terminator TSS_2453 TSS_2453

Gene      
Name: mdtQ    Texpresso search in the literature
Synonym(s): ECK2131, ECK2132, EG12020, b2138, b2139, yohG, yohH
Type: Pseudo Gene
Genome position(nucleotides): 2227323 <-- 2228758 Genome Browser
Strand: reverse
Sequence: Get nucleotide sequence FastaFormat
GC content %:  
55.15
External database links:  
ASAP:
ABE-0285124
ASAP:
ABE-0007071
ASAP:
ABE-0007067
ECHOBASE:
EB4379
ECHOBASE:
EB1956
ECOLIHUB:
mdtQ
ECOLIHUB:
yohH
ECOLIWIKI:
b2139
OU-MICROARRAY:
b2138
OU-MICROARRAY:
b2139
STRING:
316407.85675252
UNIPROT:
P33369
COLOMBOS: mdtQ


Product      
Name: putative multidrug resistance outer membrane protein MdtQ
Sequence: Get amino acid sequence Fasta Format
Isoelectric point: 12.603
Motif(s):
 
Type Positions Sequence
1 -> 21 MNRDSFYPAIACFPLLLMLAG

 

Classification:
Multifun Terms (GenProtEC)  
Gene Ontology Terms (GO)  
cellular_component GO:0009279 - cell outer membrane
GO:0016020 - membrane
GO:0016021 - integral component of membrane
molecular_function GO:0015562 - efflux transmembrane transporter activity
GO:0022857 - transmembrane transporter activity
biological_process GO:0046677 - response to antibiotic
GO:0055085 - transmembrane transport
Note(s): Note(s): ...[more].
Evidence: [HIFS] Human inference of function from sequence
Reference(s): [1] Sulavik MC., et al., 2001
External database links:  
ECOCYC:
EG12020-MONOMER
ECOLIWIKI:
b2138
INTERPRO:
IPR003423
INTERPRO:
IPR010131
MODBASE:
P33369
PFAM:
PF02321
PRIDE:
P33369
PROSITE:
PS51257
REFSEQ:
NP_416643
SMR:
P33369
UNIPROT:
P33369


Operon      
Name: mdtQ         
Operon arrangement:
Transcription unit        Promoter
mdtQ


RNA cis-regulatory element    
Attenuation: Translational


Elements in the selected gene context region unrelated to any object in RegulonDB      

  Type Name Post Left Post Right Strand Notes Evidence (Confirmed, Strong, Weak) References
  promoter TSS_2453 2227296 reverse nd [RS-EPT-CBR] [2]


Evidence    

 [RS-EPT-CBR] RNA-seq using two enrichment strategies for primary transcripts and consistent biological replicates



Reference(s)    

 [1] Sulavik MC., Houseweart C., Cramer C., Jiwani N., Murgolo N., Greene J., DiDomenico B., Shaw KJ., Miller GH., Hare R., Shimer G., 2001, Antibiotic susceptibility profiles of Escherichia coli strains lacking multidrug efflux pump genes., Antimicrob Agents Chemother 45(4):1126-36

 [2] Salgado H, Peralta-Gil M, Gama-Castro S, Santos-Zavaleta A, Muñiz-Rascado L, García-Sotelo JS, Weiss V, Solano-Lira H, Martínez-Flores I, Medina-Rivera A, Salgado-Osorio G, Alquicira-Hernández S, Alquicira-Hernández K, López-Fuentes A, Porrón-Sotelo L, Huerta AM, Bonavides-Martínez C, Balderas-Martínez YI, Pannier L, Olvera M, Labastida A, Jiménez-Jacinto V, Vega-Alvarado L, Del Moral-Chávez V, Hernández-Alvarez A, Morett E, Collado-Vides J., 2012, RegulonDB v8.0: omics data sets, evolutionary conservation, regulatory phrases, cross-validated gold standards and more., Nucleic Acids Res.


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