RegulonDB RegulonDB 10.9: Gene Form
   

arfB gene in Escherichia coli K-12 genome


Gene local context to scale (view description)

Gene      
Name: arfB    Texpresso search in the literature
Synonym(s): ECK0191, EG12354, b0191, yaeJ
Genome position(nucleotides): 214833 --> 215255 Genome Browser
Strand: forward
Sequence: Get nucleotide sequence FastaFormat
GC content %:  
54.14
External database links:  
ASAP:
ABE-0000650
ECHOBASE:
EB2258
ECOLIHUB:
yaeJ
OU-MICROARRAY:
b0191
STRING:
511145.b0191
COLOMBOS: arfB


Product      
Name: peptidyl-tRNA hydrolase, ribosome rescue factor
Synonym(s): ArfB, YaeJ
Sequence: Get amino acid sequence Fasta Format
Cellular location: cytosol
Molecular weight: 15.623
Isoelectric point: 11.418
Motif(s):
 
Type Positions Sequence
28 -> 28 Q
8 -> 132 VAIPDGELEITAIRAQGAGGQHVNKTSTAIHLRFDIRASSLPEYYKERLLAASHHLISSDGVIVIKAQEYRSQELNREAALARLVAMIKELTTEKKARRPTRPTRASKERRLASKAQKSSVKAMR
26 -> 27 GG
27 -> 28 GQ

 

Classification:
Multifun Terms (GenProtEC)  
  2 - information transfer --> 2.3 - protein related --> 2.3.2 - translation
Gene Ontology Terms (GO)  
cellular_component GO:0005737 - cytoplasm
GO:0005829 - cytosol
molecular_function GO:0003747 - translation release factor activity
GO:0016787 - hydrolase activity
GO:0043022 - ribosome binding
GO:0004045 - aminoacyl-tRNA hydrolase activity
biological_process GO:0006417 - regulation of translation
GO:0006415 - translational termination
GO:0072344 - rescue of stalled ribosome
Note(s): Note(s): ...[more].
Reference(s): [1] Kogure H., et al., 2014
[2] Ohtake K., et al., 2012
External database links:  
ECOCYC:
EG12354-MONOMER
ECOLIWIKI:
b0191
INTERPRO:
IPR000352
MODBASE:
P40711
PDB:
2RTX
PDB:
4V95
PFAM:
PF00472
PRIDE:
P40711
PROSITE:
PS00745
REFSEQ:
NP_414733
SMR:
P40711
UNIPROT:
P40711


Operon      
Name: yaeQ-arfB-nlpE         
Operon arrangement:
Transcription unit        Promoter
yaeQ-arfB-nlpE


Transcriptional Regulation      
Display Regulation             
Repressed by: CRP


Elements in the selected gene context region unrelated to any object in RegulonDB      

  Type Name Post Left Post Right Strand Notes Evidence (Confirmed, Strong, Weak) References
  promoter yaeQp3 214088 forward Similarity to the consensus
Read more >
[ICWHO] [3]
  promoter TSS_393 214163 reverse nd [RS-EPT-CBR] [4]
  promoter yaeQp6 214195 forward Similarity to the consensus
Read more >
[ICWHO] [3]
  promoter TSS_394 214197 reverse nd [RS-EPT-CBR] [4]
  promoter TSS_395 214269 forward nd [RS-EPT-CBR] [4]
  promoter TSS_396 215265 forward nd [RS-EPT-CBR] [4]



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