RegulonDB

Gene
Name:	dppB
Synonym(s):	ECK3530, EG12625, b3543
Genome position(nucleotides):	3704771 <-- 3705790
Strand:	reverse
Sequence:	Get nucleotide sequence FastaFormat
GC content %:	56.47
External database links:

ASAP:	ABE-0011572
CGSC:	33771
ECHOBASE:	EB2509
ECOLIHUB:	dppB
OU-MICROARRAY:	b3543
STRING:	511145.b3543
COLOMBOS:	dppB

Product

Name:

dipeptide ABC transporter membrane subunit DppB

Synonym(s):

DppB

Sequence:

Get amino acid sequence Fasta Format

Cellular location:

inner membrane

Molecular weight:

37.497

Isoelectric point:

9.004

Motif(s):

Type	Positions	Sequence	Comment
	1 -> 77	MLQFILRRLGLVIPTFIGITLLTFAFVHMIPGDPVMIMAGERGISPERHAQLLAELGLDKPMWQQYLHYIWGVMHGD
	10 -> 30	GLVIPTFIGITLLTFAFVHMI	UniProt: Helical.
	96 -> 328	FQATLELGVCAMIFATAVGIPVGVLAAVKRGSIFDHTAVGLALTGYSMPIFWWGMMLIMLVSVHWNLTPVSGRVSDMVFLDDSNPLTGFMLIDTAIWGEDGNFIDAVAHMILPAIVLGTIPLAVIVRMTRSSMLEVLGEDYIRTARAKGLTRMRVIIVHALRNAMLPVVTVIGLQVGTLLAGAILTETIFSWPGLGRWLIDALQRRDYPVVQGGVLLVATMIILVNLLVDLLY	UniProt: ABC transmembrane type-1.
	103 -> 123	GVCAMIFATAVGIPVGVLAAV	UniProt: Helical.
	114 -> 336	GIPVGVLAAVKRGSIFDHTAVGLALTGYSMPIFWWGMMLIMLVSVHWNLTPVSGRVSDMVFLDDSNPLTGFMLIDTAIWGEDGNFIDAVAHMILPAIVLGTIPLAVIVRMTRSSMLEVLGEDYIRTARAKGLTRMRVIIVHALRNAMLPVVTVIGLQVGTLLAGAILTETIFSWPGLGRWLIDALQRRDYPVVQGGVLLVATMIILVNLLVDLLYGVVNPRIR

Classification:

Multifun Terms (GenProtEC)
		6 - cell structure --> 6.1 - membrane
		4 - transport --> 4.3 - Primary Active Transporters --> 4.3.A - Pyrophosphate Bond (ATP; GTP; P2) Hydrolysis-driven Active Transporters --> 4.3.A.1 - The ATP-binding Cassette (ABC) Superfamily + ABC-type Uptake Permeases --> 4.3.A.1.m - ABC superfamily, membrane component
Gene Ontology Terms (GO)
	cellular_component	GO:0016020 - membrane GO:0005886 - plasma membrane GO:0005887 - integral component of plasma membrane GO:0016021 - integral component of membrane GO:0055052 - ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing
	molecular_function	GO:0071916 - dipeptide transmembrane transporter activity
	biological_process	GO:0035351 - heme transmembrane transport GO:0015031 - protein transport GO:0015833 - peptide transport GO:0015886 - heme transport GO:0042938 - dipeptide transport GO:0055085 - transmembrane transport GO:0035442 - dipeptide transmembrane transport

Note(s):

Note(s): ...[more].

External database links:

ALPHAFOLD:

DIP:

ECOCYC:

ECOLIWIKI:

INTERPRO:

INTERPRO:

PFAM:

PFAM:

PRIDE:

PRODB:

PROSITE:

REFSEQ:

UNIPROT:

Operon

Name:

dppABCDF

Operon arrangement:

Transcription unit	Promoter
dppABCDF	dppAp

Transcriptional Regulation
	Display Regulation
Activated by:	IHF
Repressed by:	FNR

RNA cis-regulatory element

Attenuation:	Translational

Regulation by small RNA
	Display Regulation
small RNA	spf

Elements in the selected gene context region unrelated to any object in RegulonDB

Type	Name	Post Left	Strand	Notes	Evidence (Confirmed, Strong, Weak)	References
promoter	TSS_4142	3704129	reverse	nd	[RS-EPT-CBR]	[1]
promoter	TSS_4143	3704681	reverse	nd	[RS-EPT-CBR]	[1]
promoter	TSS_4144 (cluster)	3704734	reverse	nd	[RS-EPT-CBR]	[1]
promoter	TSS_4145	3704861	reverse	nd	[RS-EPT-CBR]	[1]
promoter	TSS_4146	3704911	reverse	nd	[RS-EPT-CBR]	[1]
promoter	TSS_4147	3706267	reverse	nd	[RS-EPT-CBR]	[1]
promoter	TSS_4148	3706923	reverse	nd	[RS-EPT-CBR]	[1]
promoter	TSS_4149	3706927	reverse	nd	[RS-EPT-CBR]	[1]
promoter	TSS_4150 (cluster)	3707044	reverse	nd	[RS-EPT-CBR]	[1]
promoter	TSS_4151	3707053	reverse	nd	[RS-EPT-CBR]	[1]
promoter	TSS_4152	3707203	reverse	nd	[RS-EPT-CBR]	[1]
promoter	TSS_4153	3707508	reverse	nd	[RS-EPT-CBR]	[1]
promoter	TSS_4154 (cluster)	3707699	reverse	nd	[RS-EPT-CBR]	[1]

Evidence
[RS-EPT-CBR] RNA-seq using two enrichment strategies for primary transcripts and consistent biological replicates

Reference(s)
[1] Salgado H, Peralta-Gil M, Gama-Castro S, Santos-Zavaleta A, Muñiz-Rascado L, García-Sotelo JS, Weiss V, Solano-Lira H, Martínez-Flores I, Medina-Rivera A, Salgado-Osorio G, Alquicira-Hernández S, Alquicira-Hernández K, López-Fuentes A, Porrón-Sotelo L, Huerta AM, Bonavides-Martínez C, Balderas-Martínez YI, Pannier L, Olvera M, Labastida A, Jiménez-Jacinto V, Vega-Alvarado L, Del Moral-Chávez V, Hernández-Alvarez A, Morett E, Collado-Vides J., 2012, RegulonDB v8.0: omics data sets, evolutionary conservation, regulatory phrases, cross-validated gold standards and more., Nucleic Acids Res.

Reference(s)

[1] Salgado H, Peralta-Gil M, Gama-Castro S, Santos-Zavaleta A, Muñiz-Rascado L, García-Sotelo JS, Weiss V, Solano-Lira H, Martínez-Flores I, Medina-Rivera A, Salgado-Osorio G, Alquicira-Hernández S, Alquicira-Hernández K, López-Fuentes A, Porrón-Sotelo L, Huerta AM, Bonavides-Martínez C, Balderas-Martínez YI, Pannier L, Olvera M, Labastida A, Jiménez-Jacinto V, Vega-Alvarado L, Del Moral-Chávez V, Hernández-Alvarez A, Morett E, Collado-Vides J., 2012, RegulonDB v8.0: omics data sets, evolutionary conservation, regulatory phrases, cross-validated gold standards and more., Nucleic Acids Res.