RegulonDB RegulonDB 11.1: Gene Form
   

eutB gene in Escherichia coli K-12 genome


Gene local context to scale (view description)

eutB intZ eutC terminator anti-terminator intZp3 intZp3

Gene      
Name: eutB    Texpresso search in the literature
Synonym(s): ECK2436, EG50006, b2441
Genome position(nucleotides): 2557318 <-- 2558679
Strand: reverse
Sequence: Get nucleotide sequence FastaFormat
GC content %:  
 55.65
External database links:  
ASAP:
 ABE-0008046
ECHOBASE:
 EB4299
ECOLIHUB:
 eutB
OU-MICROARRAY:
 b2441
STRING:
 511145.b2441
COLOMBOS: eutB


Product      
Name: ethanolamine ammonia-lyase subunit α
Synonym(s): EutB
Sequence: Get amino acid sequence Fasta Format
Cellular location: cytosol
Molecular weight: 49.403
Isoelectric point: 4.546
Motif(s):
 
Type Positions Sequence Comment
12 -> 444 YQFKDVKEVLAKANELRSGDVLAGVAAASSQERVAAKQVLSEMTVADIRNNPVIAYEDDCVTRLIQDDVNETAYNQIKNWSISELREYVLSDETSVDDIAFTRKGLTSEVVAAVAKICSNADLIYGAKKMPVIKKANTTIGIPGTFSARLQPNDTRDDVQSIAAQIYEGLSFGVGDAVIGVNPVTDDVENLSRVLDTIYGVIDKFNIPTQGCVLAHVTTQIEAIRRGAPGGLIFQSICGSEKGLKEFGVELAMLDEARAVGAEFNRIAGENCLYFETGQGSALSAGANFGADQVTMEARNYGLARHYDPFIVNTVVGFIGPEYLYNDRQIIRAGLEDHFMGKLSGISMGCDCCYTNHADADQNLNENLMILLATAGCNYIMGMPLGDDIMLNYQTTAFHDTATVRQLLNLRPSPEFERWLESMGIMANGRLTK
160 -> 162 RLQ UniProt: Substrate binding; Sequence Annotation Type: region of interest.

 
Classification:
Multifun Terms (GenProtEC)  
  1 - metabolism --> 1.1 - carbon utilization --> 1.1.4 - amines
Gene Ontology Terms (GO)  
cellular_component GO:0005829 - cytosol
GO:0009350 - ethanolamine ammonia-lyase complex
molecular_function GO:0003824 - catalytic activity
GO:0016829 - lyase activity
GO:0008851 - ethanolamine ammonia-lyase activity
GO:0031419 - cobalamin binding
biological_process GO:0006520 - cellular amino acid metabolic process
GO:0046336 - ethanolamine catabolic process
External database links:  
ALPHAFOLD:
 P0AEJ6
ECOCYC:
 EUTB-MONOMER
ECOLIWIKI:
 b2441
INTERPRO:
 IPR010628
INTERPRO:
 IPR013785
PANTHER:
 PTHR39329
PDB:
 5YSR
PDB:
 5YSN
PDB:
 3AO0
PDB:
 3ANY
PDB:
 3ABS
PDB:
 3ABR
PDB:
 3ABO
PDB:
 3ABQ
PFAM:
 PF06751
PRIDE:
 P0AEJ6
PRODB:
 PRO_000022536
REFSEQ:
 NP_416936
SMR:
 P0AEJ6
UNIPROT:
 P0AEJ6


Operon      
Name: eutBCLKR         
Operon arrangement:
Transcription unit        Promoter
eutBCLKR


Elements in the selected gene context region unrelated to any object in RegulonDB      

  Type Name Post Left Post Right Strand Notes Evidence (Confirmed, Strong, Weak) References
  promoter intZp3 2558693 forward nd [COMP-AINF] [1]


Evidence    

 [COMP-AINF] Inferred computationally without human oversight


Reference(s)    

 [1] Huerta AM., Collado-Vides J., 2003, Sigma70 promoters in Escherichia coli: specific transcription in dense regions of overlapping promoter-like signals., J Mol Biol 333(2):261-78

RegulonDB