RegulonDB

Gene
Name:	ynfH
Synonym(s):	ECK1585, G6848, b1590
Genome position(nucleotides):	1663609 --> 1664463
Strand:	forward
Sequence:	Get nucleotide sequence FastaFormat
GC content %:	52.63
External database links:

ASAP:	ABE-0005311
ECHOBASE:	EB3607
ECOLIHUB:	ynfH
OU-MICROARRAY:	b1590
STRING:	511145.b1590
COLOMBOS:	ynfH

Product

Name:

putative menaquinol dehydrogenase

Synonym(s):

YnfH

Sequence:

Get amino acid sequence Fasta Format

Cellular location:

inner membrane

Molecular weight:

30.524

Isoelectric point:

9.414

Motif(s):

Type	Positions	Sequence	Comment
	1 -> 274	MGNGWHEWPLVIFTVLGQCVVGALIVSGIGWFAAKNDADRQRIVRGMFFLWLLMGVGFIASVMHLGSPLRAFNSLNRIGASGLSNEIAAGSIFFAVGGLWWLVAVIGKMPQALGKLWLLFSMALGVIFVWMMTCVYQIDTVPTWHNGYTTLAFFLTVLLSGPILAAAILRAARVTFNTTPFAIISVLALIACAGVIVLQGLSLASIHSSVQQASALVPDYASLQVWRVVLLCAGLGCWLCPLIRRREPHVAGLILGLILILGGEMIGRVLFYGL
	10 -> 30	LVIFTVLGQCVVGALIVSGIG	UniProt: Helical.
	46 -> 66	GMFFLWLLMGVGFIASVMHLG	UniProt: Helical.
	87 -> 107	IAAGSIFFAVGGLWWLVAVIG	UniProt: Helical.
	116 -> 136	LWLLFSMALGVIFVWMMTCVY	UniProt: Helical.

Classification:

Multifun Terms (GenProtEC)
Multifun Terms (GenProtEC)		1 - metabolism --> 1.8 - metabolism of other compounds
Gene Ontology Terms (GO)
	cellular_component	GO:0016020 - membrane GO:0005886 - plasma membrane GO:0016021 - integral component of membrane GO:0009390 - dimethyl sulfoxide reductase complex GO:1990204 - oxidoreductase complex
	molecular_function	GO:0016491 - oxidoreductase activity GO:0009389 - dimethyl sulfoxide reductase activity
	biological_process	GO:0009061 - anaerobic respiration GO:0019645 - anaerobic electron transport chain

Note(s):

Note(s): ...[more].

Reference(s):

[1] Geijer P., et al., 2004

External database links:

ALPHAFOLD:

ECOCYC:

ECOLIWIKI:

INTERPRO:

PANTHER:

PFAM:

PRIDE:

REFSEQ:

UNIPROT:

Operon

Name:

ynfEFGH-dmsD

Operon arrangement:

Transcription unit	Promoter
ynfEFGH-dmsD	ynfEp
ynfEFGH-dmsD	ynfEp2

Transcriptional Regulation
	Display Regulation
Activated by:	FNR
Repressed by:	NarL

Elements in the selected gene context region unrelated to any object in RegulonDB

	Type	Name	Post Left	Post Right	Strand	Notes	Evidence (Confirmed, Strong, Weak)	References
	promoter	TSS_1875	1664208		forward	nd	[RS-EPT-CBR]	[2]

Evidence
[RS-EPT-CBR] RNA-seq using two enrichment strategies for primary transcripts and consistent biological replicates

Reference(s)
[1] Geijer P., Weiner JH., 2004, Glutamate 87 is important for menaquinol binding in DmsC of the DMSO reductase (DmsABC) from Escherichia coli., Biochim Biophys Acta 1660(1-2):66-74
[2] Salgado H, Peralta-Gil M, Gama-Castro S, Santos-Zavaleta A, Muñiz-Rascado L, García-Sotelo JS, Weiss V, Solano-Lira H, Martínez-Flores I, Medina-Rivera A, Salgado-Osorio G, Alquicira-Hernández S, Alquicira-Hernández K, López-Fuentes A, Porrón-Sotelo L, Huerta AM, Bonavides-Martínez C, Balderas-Martínez YI, Pannier L, Olvera M, Labastida A, Jiménez-Jacinto V, Vega-Alvarado L, Del Moral-Chávez V, Hernández-Alvarez A, Morett E, Collado-Vides J., 2012, RegulonDB v8.0: omics data sets, evolutionary conservation, regulatory phrases, cross-validated gold standards and more., Nucleic Acids Res.

Reference(s)

[1] Geijer P., Weiner JH., 2004, Glutamate 87 is important for menaquinol binding in DmsC of the DMSO reductase (DmsABC) from Escherichia coli., Biochim Biophys Acta 1660(1-2):66-74

[2] Salgado H, Peralta-Gil M, Gama-Castro S, Santos-Zavaleta A, Muñiz-Rascado L, García-Sotelo JS, Weiss V, Solano-Lira H, Martínez-Flores I, Medina-Rivera A, Salgado-Osorio G, Alquicira-Hernández S, Alquicira-Hernández K, López-Fuentes A, Porrón-Sotelo L, Huerta AM, Bonavides-Martínez C, Balderas-Martínez YI, Pannier L, Olvera M, Labastida A, Jiménez-Jacinto V, Vega-Alvarado L, Del Moral-Chávez V, Hernández-Alvarez A, Morett E, Collado-Vides J., 2012, RegulonDB v8.0: omics data sets, evolutionary conservation, regulatory phrases, cross-validated gold standards and more., Nucleic Acids Res.