RegulonDB RegulonDB 10.9: Gene Form
   

mdtJ gene in Escherichia coli K-12 genome


Gene local context to scale (view description)

Gene      
Name: mdtJ    Texpresso search in the literature
Synonym(s): ECK1595, G6858, b1600, ydgF
Genome position(nucleotides): 1673136 <-- 1673501 Genome Browser
Strand: reverse
Sequence: Get nucleotide sequence FastaFormat
GC content %:  
42.35
External database links:  
ASAP:
ABE-0005345
ECHOBASE:
EB3686
ECOLIHUB:
mdtJ
OU-MICROARRAY:
b1600
STRING:
511145.b1600
COLOMBOS: mdtJ


Product      
Name: multidrug/spermidine efflux pump membrane subunit MdtJ
Synonym(s): Em121, MdtJ, YdgF
Sequence: Get amino acid sequence Fasta Format
Cellular location: inner membrane
Molecular weight: 13.115
Isoelectric point: 9.487
Motif(s):
 
Type Positions Sequence
61 -> 61 Y
85 -> 106 SLMKIAGLTTLVAGIVLIKSGT
5 -> 5 W
32 -> 52 GGFILMLVMISLSYIFLSFAV
55 -> 75 IALGVAYALWEGIGILFITLF

 

Classification:
Multifun Terms (GenProtEC)  
  4 - transport --> 4.2 - Electrochemical potential driven transporters --> 4.2.A - Porters (Uni-, Sym- and Antiporters)
  5 - cell processes --> 5.6 - protection --> 5.6.4 - drug resistance/sensitivity
  6 - cell structure --> 6.1 - membrane
Gene Ontology Terms (GO)  
cellular_component GO:0016020 - membrane
GO:0005886 - plasma membrane
GO:0005887 - integral component of plasma membrane
GO:0016021 - integral component of membrane
molecular_function GO:0015297 - antiporter activity
GO:0022857 - transmembrane transporter activity
GO:0015606 - spermidine transmembrane transporter activity
GO:0015199 - amino-acid betaine transmembrane transporter activity
GO:0015220 - choline transmembrane transporter activity
biological_process GO:1990961 - xenobiotic detoxification by transmembrane export across the plasma membrane
GO:0015848 - spermidine transport
GO:0055085 - transmembrane transport
GO:0031460 - glycine betaine transport
GO:0015871 - choline transport
GO:1903711 - spermidine transmembrane transport
Note(s): Note(s): ...[more].
Reference(s): [1] Hirakawa H., et al., 2003
[2] Jindal S., et al., 2019
[3] Nishino K., et al., 2002
External database links:  
ECOCYC:
B1600-MONOMER
ECOLIWIKI:
b1600
INTERPRO:
IPR023740
INTERPRO:
IPR000390
MODBASE:
P69212
PANTHER:
PTHR30561
PANTHER:
PTHR30561:SF2
PFAM:
PF00893
PRIDE:
P69212
PRODB:
PRO_000023190
REFSEQ:
NP_416117
SMR:
P69212
UNIPROT:
P69212


Operon      
Name: mdtJI         
Operon arrangement:
Transcription unit        Promoter
mdtJI


Transcriptional Regulation      
Display Regulation             
Repressed by: H-NS


Elements in the selected gene context region unrelated to any object in RegulonDB      

  Type Name Post Left Post Right Strand Notes Evidence (Confirmed, Strong, Weak) References
  promoter TSS_1879 (cluster) 1671972 forward For this promoter, there
Read more >
[RS-EPT-CBR] [4]



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