RegulonDB RegulonDB 11.1: Gene Form
   

yfgO gene in Escherichia coli K-12 genome


Gene local context to scale (view description)

bepA yfgO focB TSS_2777 TSS_2777 TSS_2776 TSS_2776 TSS_2775 TSS_2775 bepAp1 bepAp1 bepAp2 bepAp2

Gene      
Name: yfgO    Texpresso search in the literature
Synonym(s): ECK2489, G7310, b2493, perM
Genome position(nucleotides): 2614820 <-- 2615881
Strand: reverse
Sequence: Get nucleotide sequence FastaFormat
GC content %:  
 54.14
External database links:  
ASAP:
 ABE-0008208
ECHOBASE:
 EB3973
ECOLIHUB:
 yfgO
OU-MICROARRAY:
 b2493
STRING:
 511145.b2493
COLOMBOS: yfgO


Product      
Name: putative transporter YfgO
Synonym(s): PerM, YfgO
Sequence: Get amino acid sequence Fasta Format
Cellular location: inner membrane
Molecular weight: 39.194
Isoelectric point: 9.297
Motif(s):
 
Type Positions Sequence Comment
19 -> 39 IALLVILVAGFGIIFFFSGLL UniProt: Helical.
20 -> 345 ALLVILVAGFGIIFFFSGLLAPLLVAIVLAYLLEWPTVRLQSIGCSRRWATSIVLVVFVGILLLMAFVVLPIAWQQGIYLIRDMPGMLNKLSDFAATLPRRYPALMDAGIIDAMAENMRSRMLTMGDSVVKISLASLVGLLTIAVYLVLVPLMVFFLLKDKEQMLNAVRRVLPRNRGLAGQVWKEMNQQITNYIRGKVLEMIVVGIATWLGFLLFGLNYSLLLAVLVGFSVLIPYIGAFVVTIPVVGVALFQFGAGTEFWSCFAVYLIIQALDGNLLVPVLFSEAVNLHPLVIILSVVIFGGLWGFWGVFFAIPLATLIKAVIHAW
72 -> 92 IVLVVFVGILLLMAFVVLPIA UniProt: Helical.
156 -> 176 LVGLLTIAVYLVLVPLMVFFL UniProt: Helical.
217 -> 237 VLEMIVVGIATWLGFLLFGLN UniProt: Helical.

 
Classification:
Multifun Terms (GenProtEC)  
  6 - cell structure --> 6.1 - membrane
Gene Ontology Terms (GO)  
cellular_component GO:0016020 - membrane
GO:0005886 - plasma membrane
GO:0016021 - integral component of membrane
biological_process GO:0055085 - transmembrane transport
Note(s): Note(s): ...[more].
Reference(s): [1] Jindal S., et al., 2019
External database links:  
ALPHAFOLD:
 P0AFI9
ECOCYC:
 G7310-MONOMER
ECOLIWIKI:
 b2493
INTERPRO:
 IPR002549
PANTHER:
 PTHR21716
PFAM:
 PF01594
PRIDE:
 P0AFI9
REFSEQ:
 NP_416988
UNIPROT:
 P0AFI9


Operon      
Name: yfgO         
Operon arrangement:
Transcription unit        Promoter
yfgO


Elements in the selected gene context region unrelated to any object in RegulonDB      

  Type Name Post Left Post Right Strand Notes Evidence (Confirmed, Strong, Weak) References
  promoter TSS_2775 2617541 forward nd [RS-EPT-CBR] [2]
  promoter TSS_2776 2617552 forward nd [RS-EPT-CBR] [2]
  promoter TSS_2777 2617557 forward nd [RS-EPT-CBR] [2]


Evidence    

 [RS-EPT-CBR] RNA-seq using two enrichment strategies for primary transcripts and consistent biological replicates


Reference(s)    

 [1] Jindal S., Yang L., Day PJ., Kell DB., 2019, Involvement of multiple influx and efflux transporters in the accumulation of cationic fluorescent dyes by Escherichia coli., BMC Microbiol 19(1):195

 [2] Salgado H, Peralta-Gil M, Gama-Castro S, Santos-Zavaleta A, Muñiz-Rascado L, García-Sotelo JS, Weiss V, Solano-Lira H, Martínez-Flores I, Medina-Rivera A, Salgado-Osorio G, Alquicira-Hernández S, Alquicira-Hernández K, López-Fuentes A, Porrón-Sotelo L, Huerta AM, Bonavides-Martínez C, Balderas-Martínez YI, Pannier L, Olvera M, Labastida A, Jiménez-Jacinto V, Vega-Alvarado L, Del Moral-Chávez V, Hernández-Alvarez A, Morett E, Collado-Vides J., 2012, RegulonDB v8.0: omics data sets, evolutionary conservation, regulatory phrases, cross-validated gold standards and more., Nucleic Acids Res.

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