RegulonDB RegulonDB 11.1: Gene Form
   

pdeF gene in Escherichia coli K-12 genome


Gene local context to scale (view description)

pdeF ppx yfgG FNR yfgGp yfgGp yfgFp yfgFp

Gene      
Name: pdeF    Texpresso search in the literature
Synonym(s): ECK2499, G7314, b2503, yfgF
Genome position(nucleotides): 2626695 <-- 2628938
Strand: reverse
Sequence: Get nucleotide sequence FastaFormat
GC content %:  
 46.61
External database links:  
ASAP:
 ABE-0008240
ECHOBASE:
 EB3954
ECOLIHUB:
 yfgF
OU-MICROARRAY:
 b2503
STRING:
 511145.b2503
COLOMBOS: pdeF


Product      
Name: cyclic di-GMP phosphodiesterase PdeF
Synonym(s): PdeF, YfgF
Sequence: Get amino acid sequence Fasta Format
Cellular location: inner membrane
Molecular weight: 85.608
Isoelectric point: 8.916
Motif(s):
 
Type Positions Sequence Comment
15 -> 320 WGLPLFLPSLILPIFAHINTFAHISSGEVFLFYLPLALMISMMMFFSWAALPGIALGIFVRKYAELGFYETLSLTANFIIIIILCWGGYRVFTPRRNNVSHGDTRLISQRIFWQIVFPATLFLILFQFAAFVGLLASRENLVGVMPFNLGTLINYQALLVGNLIGVPLCYFIIRVVRNPFYLRSYYSQLKQQVDAKVTKKEFALWLLALGALLLLLCMPLNEKSTIFSTNYTLSLLLPLMMWGAMRYGYKLISLLWAVVLMISIHSYQNYIPIYPGYTTQLTITSSSYLVFSFIVNYMAVLATRQR
43 -> 65 VFLFYLPLALMISMMMFFSWAAL UniProt: Helical.
80 -> 102 LGFYETLSLTANFIIIIILCWGG UniProt: Helical.
129 -> 151 IVFPATLFLILFQFAAFVGLLAS UniProt: Helical.
166 -> 188 LINYQALLVGNLIGVPLCYFIIR UniProt: Helical.

 
Classification:
Multifun Terms (GenProtEC)  
  5 - cell processes --> 5.5 - adaptations
Gene Ontology Terms (GO)  
cellular_component GO:0016020 - membrane
GO:0005886 - plasma membrane
GO:0016021 - integral component of membrane
molecular_function GO:0016787 - hydrolase activity
GO:0000166 - nucleotide binding
GO:0042803 - protein homodimerization activity
GO:0071111 - cyclic-guanylate-specific phosphodiesterase activity
biological_process GO:0070301 - cellular response to hydrogen peroxide
GO:0071454 - cellular response to anoxia
GO:1900190 - regulation of single-species biofilm formation
External database links:  
ALPHAFOLD:
 P77172
DIP:
 DIP-12038N
ECOCYC:
 G7314-MONOMER
ECOLIWIKI:
 b2503
INTERPRO:
 IPR035919
INTERPRO:
 IPR007895
INTERPRO:
 IPR001633
INTERPRO:
 IPR000160
PFAM:
 PF00563
PFAM:
 PF05231
PRIDE:
 P77172
PROSITE:
 PS50883
REFSEQ:
 NP_416998
SMART:
 SM00052
SMART:
 SM00267
SMR:
 P77172
UNIPROT:
 P77172


Operon      
Name: pdeF         
Operon arrangement:
Transcription unit        Promoter
yfgF


Transcriptional Regulation      
Display Regulation             
Activated by: FNR


Elements in the selected gene context region unrelated to any object in RegulonDB      

  Type Name Post Left Post Right Strand Notes Evidence (Confirmed, Strong, Weak) References



RegulonDB