RegulonDB RegulonDB 11.1: Gene Form
   

casD gene in Escherichia coli K-12 genome


Gene local context to scale (view description)

casC cas1 casD casE ygbFp ygbFp

Gene      
Name: casD    Texpresso search in the literature
Synonym(s): ECK2752, G7427, b2757, cas5e, ygcI
Genome position(nucleotides): 2880374 <-- 2881048
Strand: reverse
Sequence: Get nucleotide sequence FastaFormat
GC content %:  
 48.15
External database links:  
ASAP:
 ABE-0009044
ECHOBASE:
 EB2917
ECOLIHUB:
 casD
OU-MICROARRAY:
 b2757
STRING:
 511145.b2757
COLOMBOS: casD


Product      
Name: type I-E CRISPR system Cascade subunit CasD
Synonym(s): Cas5e, CasD, Cascade subunit D, YgcI
Sequence: Get amino acid sequence Fasta Format
Cellular location: cytosol
Molecular weight: 25.209
Isoelectric point: 7.497
Motif(s):
 
Type Positions Sequence Comment
4 -> 179 YLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESVQFAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHETIQTWREYLCDASFTVALWLTPHATMVISELEKAVLKPRYTPYLGRRSCPLTHPLFLGTCQASDPQKALLNYEPVGG

 
Classification:
Multifun Terms (GenProtEC)  
  5 - cell processes --> 5.10 - defense/survival
Gene Ontology Terms (GO)  
cellular_component GO:0005829 - cytosol
GO:0032991 - protein-containing complex
molecular_function GO:0005515 - protein binding
GO:0003723 - RNA binding
GO:0071667 - DNA/RNA hybrid binding
biological_process GO:0099048 - CRISPR-cas system
GO:0051607 - defense response to virus
GO:0043571 - maintenance of CRISPR repeat elements
Note(s): Note(s): ...[more].
External database links:  
ALPHAFOLD:
 Q46898
DIP:
 DIP-12125N
ECOCYC:
 G7427-MONOMER
ECOLIWIKI:
 b2757
INTERPRO:
 IPR013422
INTERPRO:
 IPR021124
INTERPRO:
 IPR010147
PDB:
 5CD4
PDB:
 4U7U
PDB:
 5H9F
PDB:
 4TVX
PDB:
 5H9E
PDB:
 4QYZ
PFAM:
 PF09704
PRIDE:
 Q46898
REFSEQ:
 NP_417237
SMR:
 Q46898
UNIPROT:
 Q46898


Operon      
Name: casABCDE12         
Operon arrangement:
Transcription unit        Promoter
ygbF
casABCDE12
casDE-ygbTF


Transcriptional Regulation      
Display Regulation             
Activated by: SlyA, LeuO, StpA
Repressed by: CRP, H-NS


Elements in the selected gene context region unrelated to any object in RegulonDB      

  Type Name Post Left Post Right Strand Notes Evidence (Confirmed, Strong, Weak) References



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