RegulonDB

Gene
Name:	kdpF
Synonym(s):	ECK0687, G0-10439, b4513
Genome position(nucleotides):	728732 <-- 728821
Strand:	reverse
Sequence:	Get nucleotide sequence FastaFormat
GC content %:	48.89
External database links:

ASAP:	ABE-0285034
ECHOBASE:	EB2047
ECOLIHUB:	kdpF
STRING:	511145.b4513
COLOMBOS:	kdpF

Product

Name:

K⁺ transporting P-type ATPase subunit KdpF

Synonym(s):

KdpF

Sequence:

Get amino acid sequence Fasta Format

Cellular location:

inner membrane

Molecular weight:

3.072

Isoelectric point:

3.846

Motif(s):

Type	Positions	Sequence	Comment
	3 -> 24	AGVITGVLLVFLLLGYLVYALI
	6 -> 29	ITGVLLVFLLLGYLVYALINAEAF

Classification:

Multifun Terms (GenProtEC)
Multifun Terms (GenProtEC)		4 - transport --> 4.3 - Primary Active Transporters --> 4.3.A - Pyrophosphate Bond (ATP; GTP; P2) Hydrolysis-driven Active Transporters --> 4.3.A.3 - The P-type ATPase (P-ATPase) Superfamily
Gene Ontology Terms (GO)
	cellular_component	GO:0031004 - potassium ion-transporting ATPase complex GO:1903103 - potassium:proton antiporter complex GO:0016020 - membrane GO:0005886 - plasma membrane GO:0005887 - integral component of plasma membrane GO:0016021 - integral component of membrane
	molecular_function	GO:0008556 - P-type potassium transmembrane transporter activity
	biological_process	GO:0006811 - ion transport GO:0006813 - potassium ion transport GO:0043462 - regulation of ATP-dependent activity GO:0071805 - potassium ion transmembrane transport GO:0098655 - cation transmembrane transport

Note(s):

Note(s): ...[more].

Reference(s):

[1] Altendorf K., et al., 1998
[2] Gassel M., et al., 1999

External database links:

ALPHAFOLD:

ECOCYC:

ECOLIWIKI:

INTERPRO:

PDB:

PDB:

PDB:

PDB:

PDB:

PDB:

PDB:

PDB:

PFAM:

REFSEQ:

SMR:

UNIPROT:

Operon

Name:

kdpFABC

Operon arrangement:

Transcription unit	Promoter
kdpFABC	kdpFp

Transcriptional Regulation
	Display Regulation
Activated by:	KdpE

RNA cis-regulatory element

Attenuation:	Translational

Elements in the selected gene context region unrelated to any object in RegulonDB

Type	Name	Post Left	Strand	Notes	Evidence (Confirmed, Strong, Weak)	References
promoter	ybfAp7	729037	forward	nd	[COMP-AINF]	[3]
promoter	TSS_828 (cluster)	729071	forward	nd	[RS-EPT-CBR]	[4]
promoter	ybfAp8	729082	forward	nd	[COMP-AINF], [RS-EPT-CBR]	[3], [4]
promoter	TSS_830	729088	forward	nd	[RS-EPT-CBR]	[4]

Evidence
[COMP-AINF] Inferred computationally without human oversight
[RS-EPT-CBR] RNA-seq using two enrichment strategies for primary transcripts and consistent biological replicates

Reference(s)
[1] Altendorf K., Gassel M., Puppe W., Mollenkamp T., Zeeck A., Boddien C., Fendler K., Bamberg E., Drose S., 1998, Structure and function of the Kdp-ATPase of Escherichia coli., Acta Physiol Scand Suppl 643:137-46
[2] Gassel M., Mollenkamp T., Puppe W., Altendorf K., 1999, The KdpF subunit is part of the K(+)-translocating Kdp complex of Escherichia coli and is responsible for stabilization of the complex in vitro., J Biol Chem 274(53):37901-7
[3] Huerta AM., Collado-Vides J., 2003, Sigma70 promoters in Escherichia coli: specific transcription in dense regions of overlapping promoter-like signals., J Mol Biol 333(2):261-78
[4] Salgado H, Peralta-Gil M, Gama-Castro S, Santos-Zavaleta A, Muñiz-Rascado L, García-Sotelo JS, Weiss V, Solano-Lira H, Martínez-Flores I, Medina-Rivera A, Salgado-Osorio G, Alquicira-Hernández S, Alquicira-Hernández K, López-Fuentes A, Porrón-Sotelo L, Huerta AM, Bonavides-Martínez C, Balderas-Martínez YI, Pannier L, Olvera M, Labastida A, Jiménez-Jacinto V, Vega-Alvarado L, Del Moral-Chávez V, Hernández-Alvarez A, Morett E, Collado-Vides J., 2012, RegulonDB v8.0: omics data sets, evolutionary conservation, regulatory phrases, cross-validated gold standards and more., Nucleic Acids Res.