RegulonDB

Gene
Name:	yifL
Synonym(s):	ECK3803, G0-10471, b4558
Genome position(nucleotides):	3994522 --> 3994725 Genome Browser
Strand:	forward
Sequence:	Get nucleotide sequence FastaFormat
GC content %:	52.45
External database links:

ASAP:	ABE-0285079
ECHOBASE:	EB2257
ECOLIHUB:	yifL
STRING:	511145.b4558
COLOMBOS:	yifL

Product

Name:

putative lipoprotein YifL

Synonym(s):

YifL

Sequence:

Get amino acid sequence Fasta Format

Cellular location:

inner membrane

Molecular weight:

7.177

Isoelectric point:

9.194

Motif(s):

Type	Positions	Sequence
	8 -> 29	LTVLLTLFSLTGCGLKGPLYFP
	20 -> 67	CGLKGPLYFPPADKNAPPPTKPVETQTQSTVPDKNDRATGDGPSQVNY
	60 -> 67	DGPSQVNY
	1 -> 19	MKNVFKALTVLLTLFSLTG

Classification:

Multifun Terms (GenProtEC)
Gene Ontology Terms (GO)
Gene Ontology Terms (GO)	cellular_component	GO:0016020 - membrane GO:0005886 - plasma membrane

Note(s):

Note(s): ...[more].

Reference(s):

[1] Paradis-Bleau C., et al., 2014
[2] Rao S., et al., 2020

External database links:

ECOCYC:

ECOLIWIKI:

INTERPRO:

PFAM:

PRIDE:

PROSITE:

REFSEQ:

UNIPROT:

Operon

Name:

Operon arrangement:

Transcription unit	Promoter
yifL-dapF-yigA-xerC-yigB	yifLp

Elements in the selected gene context region unrelated to any object in RegulonDB

	Type	Name	Post Left	Post Right	Strand	Notes	Evidence (Confirmed, Strong, Weak)	References
	promoter	cyaYp5	3994083		reverse	nd	[ICWHO], [RS-EPT-CBR]	[3], [4]
	promoter	TSS_4467	3994491		forward	nd	[RS-EPT-CBR]	[4]

Evidence
[ICWHO] Inferred computationally without human oversight
[RS-EPT-CBR] RNA-seq using two enrichment strategies for primary transcripts and consistent biological replicates

Reference(s)
[1] Paradis-Bleau C., Kritikos G., Orlova K., Typas A., Bernhardt TG., 2014, A genome-wide screen for bacterial envelope biogenesis mutants identifies a novel factor involved in cell wall precursor metabolism., PLoS Genet 10(1):e1004056
[2] Rao S., Bates GT., Matthews CR., Newport TD., Vickery ON., Stansfeld PJ., 2020, Characterizing Membrane Association and Periplasmic Transfer of Bacterial Lipoproteins through Molecular Dynamics Simulations., Structure 28(4):475-487.e3
[3] Huerta AM., Collado-Vides J., 2003, Sigma70 promoters in Escherichia coli: specific transcription in dense regions of overlapping promoter-like signals., J Mol Biol 333(2):261-78
[4] Salgado H, Peralta-Gil M, Gama-Castro S, Santos-Zavaleta A, Muñiz-Rascado L, García-Sotelo JS, Weiss V, Solano-Lira H, Martínez-Flores I, Medina-Rivera A, Salgado-Osorio G, Alquicira-Hernández S, Alquicira-Hernández K, López-Fuentes A, Porrón-Sotelo L, Huerta AM, Bonavides-Martínez C, Balderas-Martínez YI, Pannier L, Olvera M, Labastida A, Jiménez-Jacinto V, Vega-Alvarado L, Del Moral-Chávez V, Hernández-Alvarez A, Morett E, Collado-Vides J., 2012, RegulonDB v8.0: omics data sets, evolutionary conservation, regulatory phrases, cross-validated gold standards and more., Nucleic Acids Res.