Gene
Name:	ampD
Synonym(s):	ECK0109, EG10041, b0110
Genome position(nucleotides):	118733 --> 119284
Strand:	forward
Sequence:	Get nucleotide sequence FastaFormat
GC content %:	53.8
External database links:

ASAP:	ABE-0000380
CGSC:	30478
ECHOBASE:	EB0039
ECOLIHUB:	ampD
OU-MICROARRAY:	b0110
STRING:	511145.b0110
COLOMBOS:	ampD

Type	Name	Post Left	Strand	Notes	Evidence (Confirmed, Strong, Weak)	References
promoter	TSS_232	118078	reverse	nd	[RS-EPT-CBR]	[4]
promoter	ampDp5	118681	forward	nd	[COMP-AINF]	[5]
promoter	TSS_233	120916	reverse	nd	[RS-EPT-CBR]	[4]
promoter	TSS_234 (cluster)	120919	reverse	nd	[RS-EPT-CBR]	[4]
promoter	TSS_235	120955	reverse	nd	[RS-EPT-CBR]	[4]

Evidence
[RS-EPT-CBR] RNA-seq using two enrichment strategies for primary transcripts and consistent biological replicates
[COMP-AINF] Inferred computationally without human oversight

Reference(s)
[1] Jacobs C., 1997, Pharmacia Biotech & Science prize. 1997 grand prize winner. Life in the balance: cell walls and antibiotic resistance., Science 278(5344):1731-2
[2] Petrosino JF., Galhardo RS., Morales LD., Rosenberg SM., 2009, Stress-induced beta-lactam antibiotic resistance mutation and sequences of stationary-phase mutations in the Escherichia coli chromosome., J Bacteriol 191(19):5881-9
[3] Tuomanen E., Lindquist S., Sande S., Galleni M., Light K., Gage D., Normark S., 1991, Coordinate regulation of beta-lactamase induction and peptidoglycan composition by the amp operon., Science 251(4990):201-4
[4] Salgado H, Peralta-Gil M, Gama-Castro S, Santos-Zavaleta A, Muñiz-Rascado L, García-Sotelo JS, Weiss V, Solano-Lira H, Martínez-Flores I, Medina-Rivera A, Salgado-Osorio G, Alquicira-Hernández S, Alquicira-Hernández K, López-Fuentes A, Porrón-Sotelo L, Huerta AM, Bonavides-Martínez C, Balderas-Martínez YI, Pannier L, Olvera M, Labastida A, Jiménez-Jacinto V, Vega-Alvarado L, Del Moral-Chávez V, Hernández-Alvarez A, Morett E, Collado-Vides J., 2012, RegulonDB v8.0: omics data sets, evolutionary conservation, regulatory phrases, cross-validated gold standards and more., Nucleic Acids Res.
[5] Huerta AM., Collado-Vides J., 2003, Sigma70 promoters in Escherichia coli: specific transcription in dense regions of overlapping promoter-like signals., J Mol Biol 333(2):261-78

Transcriptional Regulation
	Display Regulation
Repressed by:	CRP