RegulonDB RegulonDB 10.9: Gene Form
   

argT gene in Escherichia coli K-12 genome


Gene local context to scale (view description)

argT hisJ ubiX NtrC NtrC ArgR ArgR GcvB ppGpp TSS_2620 TSS_2620 argTp argTp hisJp hisJp TSS_2618 TSS_2618

Gene      
Name: argT    Texpresso search in the literature
Synonym(s): ECK2304, EG10072, b2310
Genome position(nucleotides): 2427009 <-- 2427791 Genome Browser
Strand: reverse
Sequence: Get nucleotide sequence FastaFormat
GC content %:  
50.19
External database links:  
ASAP:
ABE-0007621
CGSC:
18529
ECHOBASE:
EB0070
ECOLIHUB:
argT
OU-MICROARRAY:
b2310
STRING:
511145.b2310
COLOMBOS: argT


Product      
Name: lysine/arginine/ornithine ABC transporter periplasmic binding protein
Synonym(s): ArgT
Sequence: Get amino acid sequence Fasta Format
Cellular location: periplasmic space
Molecular weight: 27.992
Isoelectric point: 5.461
Motif(s):
 
Type Positions Sequence
213 -> 213 F
86 -> 87 ID
200 -> 201 FA
237 -> 239 GEL
1 -> 22 MKKSILALSLLVGLSTAASSYA

 

Classification:
Multifun Terms (GenProtEC)  
  1 - metabolism --> 1.5 - biosynthesis of building blocks --> 1.5.1 - amino acids --> 1.5.1.3 - arginine
  1 - metabolism --> 1.5 - biosynthesis of building blocks --> 1.5.1 - amino acids --> 1.5.1.7 - lysine
  4 - transport --> 4.3 - Primary Active Transporters --> 4.3.A - Pyrophosphate Bond (ATP; GTP; P2) Hydrolysis-driven Active Transporters --> 4.3.A.1 - The ATP-binding Cassette (ABC) Superfamily + ABC-type Uptake Permeases --> 4.3.A.1.p - ABC superfamily, periplasmic binding component
Gene Ontology Terms (GO)  
cellular_component GO:0030288 - outer membrane-bounded periplasmic space
GO:0042597 - periplasmic space
biological_process GO:0006865 - amino acid transport
GO:0009267 - cellular response to starvation
GO:0071705 - nitrogen compound transport
GO:0071294 - cellular response to zinc ion
GO:0006995 - cellular response to nitrogen starvation
GO:0015822 - ornithine transport
GO:1902022 - L-lysine transport
GO:1902023 - L-arginine transport
Note(s): Note(s): ...[more].
External database links:  
DIP:
DIP-9148N
ECOCYC:
ARGT-MONOMER
ECOLIWIKI:
b2310
INTERPRO:
IPR001638
INTERPRO:
IPR005768
INTERPRO:
IPR018313
MODBASE:
P09551
PFAM:
PF00497
PRIDE:
P09551
PRODB:
PRO_000022136
PROSITE:
PS01039
REFSEQ:
NP_416813
SMART:
SM00062
SMR:
P09551
SWISSMODEL:
P09551
UNIPROT:
P09551


Operon      
Name: argT-hisJQMP         
Operon arrangement:
Transcription unit        Promoter
hisJQMP
argT-hisJQMP


Transcriptional Regulation      
Display Regulation             
Activated by: NtrC


Elements in the selected gene context region unrelated to any object in RegulonDB      

  Type Name Post Left Post Right Strand Notes Evidence (Confirmed, Strong, Weak) References
  promoter TSS_2618 2426821 reverse nd [RS-EPT-CBR] [1]
  promoter TSS_2620 2427937 reverse nd [RS-EPT-CBR] [1]


Evidence    

 [RS-EPT-CBR] RNA-seq using two enrichment strategies for primary transcripts and consistent biological replicates



Reference(s)    

 [1] Salgado H, Peralta-Gil M, Gama-Castro S, Santos-Zavaleta A, Muñiz-Rascado L, García-Sotelo JS, Weiss V, Solano-Lira H, Martínez-Flores I, Medina-Rivera A, Salgado-Osorio G, Alquicira-Hernández S, Alquicira-Hernández K, López-Fuentes A, Porrón-Sotelo L, Huerta AM, Bonavides-Martínez C, Balderas-Martínez YI, Pannier L, Olvera M, Labastida A, Jiménez-Jacinto V, Vega-Alvarado L, Del Moral-Chávez V, Hernández-Alvarez A, Morett E, Collado-Vides J., 2012, RegulonDB v8.0: omics data sets, evolutionary conservation, regulatory phrases, cross-validated gold standards and more., Nucleic Acids Res.


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