RegulonDB

Gene
Name:	chbC
Synonym(s):	ECK1735, EG10141, b1737, celB, hic
Genome position(nucleotides):	1819856 <-- 1821214
Strand:	reverse
Sequence:	Get nucleotide sequence FastaFormat
GC content %:	49.23
External database links:

ASAP:	ABE-0005795
CGSC:	18487
ECHOBASE:	EB0139
ECOLIHUB:	chbC
OU-MICROARRAY:	b1737
STRING:	511145.b1737
COLOMBOS:	chbC

Product

Name:

N,N'-diacetylchitobiose-specific PTS enzyme IIC component

Synonym(s):

CelB, ChbC, EIIC^cel, EIIC^chb, Enzyme IIC^cel, Enzyme IIC^chb, Hic

Sequence:

Get amino acid sequence Fasta Format

Cellular location:

inner membrane

Molecular weight:

48.332

Isoelectric point:

6.971

Motif(s):

Type	Positions	Sequence	Comment
	8 -> 426	LEKVLLPFAVKIGKQPHVNAIKNGFIRLMPLTLAGAMFVLINNVFLSFGEGSFFYSLGIRLDASTIETLNGLKGIGGNVYNGTLGIMSLMAPFFIGMALAEERKVDALAAGLLSVAAFMTVTPYSVGEAYAVGANWLGGANIISGIIIGLVVAEMFTFIVRRNWVIKLPDSVPASVSRSFSALIPGFIILSVMGIIAWALNTWGTNFHQIIMDTISTPLASLGSVVGWAYVIFVPLLWFFGIHGALALTALDNGIMTPWALENIATYQQYGSVEAALAAGKTFHIWAKPMLDSFIFLGGSGATLGLILAIFIASRRADYRQVAKLALPSGIFQINEPILFGLPIIMNPVMFIPFVLVQPILAAITLAAYYMGIIPPVTNIAPWTMPTGLGAFFNTNGSVAALLVALFNLGIATLIYLPF	UniProt: PTS EIIC type-3.
	30 -> 363	NGFIRLMPLTLAGAMFVLINNVFLSFGEGSFFYSLGIRLDASTIETLNGLKGIGGNVYNGTLGIMSLMAPFFIGMALAEERKVDALAAGLLSVAAFMTVTPYSVGEAYAVGANWLGGANIISGIIIGLVVAEMFTFIVRRNWVIKLPDSVPASVSRSFSALIPGFIILSVMGIIAWALNTWGTNFHQIIMDTISTPLASLGSVVGWAYVIFVPLLWFFGIHGALALTALDNGIMTPWALENIATYQQYGSVEAALAAGKTFHIWAKPMLDSFIFLGGSGATLGLILAIFIASRRADYRQVAKLALPSGIFQINEPILFGLPIIMNPVMFIPFVL
	35 -> 55	LMPLTLAGAMFVLINNVFLSF	UniProt: Helical.
	86 -> 106	VYNGTLGIMSLMAPFFIGMAL	UniProt: Helical.
	114 -> 134	ALAAGLLSVAAFMTVTPYSVG	UniProt: Helical.

Classification:

Multifun Terms (GenProtEC)
		1 - metabolism --> 1.1 - carbon utilization --> 1.1.1 - carbon compounds
		4 - transport --> 4.4 - Group Translocators --> 4.4.A - Phosphotransferase Systems (PEP-dependent PTS)
		6 - cell structure --> 6.1 - membrane
Gene Ontology Terms (GO)
	cellular_component	GO:0016020 - membrane GO:0005886 - plasma membrane GO:0005887 - integral component of plasma membrane GO:0016021 - integral component of membrane GO:1902495 - transmembrane transporter complex
	molecular_function	GO:0008982 - protein-N(PI)-phosphohistidine-sugar phosphotransferase activity GO:0090563 - protein-phosphocysteine-sugar phosphotransferase activity
	biological_process	GO:0008643 - carbohydrate transport GO:0009401 - phosphoenolpyruvate-dependent sugar phosphotransferase system GO:0034219 - carbohydrate transmembrane transport GO:1901264 - carbohydrate derivative transport GO:1902815 - N,N'-diacetylchitobiose import

Note(s):

Note(s): ...[more].

External database links:

ALPHAFOLD:

DIP:

ECOCYC:

ECOLIWIKI:

INTERPRO:

INTERPRO:

INTERPRO:

PFAM:

PRIDE:

PRODB:

PROSITE:

REFSEQ:

UNIPROT:

Operon

Name:

chbBCARFG

Operon arrangement:

Transcription unit	Promoter
chbBCARFG	chbBp

Transcriptional Regulation
	Display Regulation
Activated by:	CRP, ChbR
Repressed by:	NagC, ChbR

RNA cis-regulatory element

Attenuation:	Translational

Regulation by small RNA
	Display Regulation
small RNA	chiX

Elements in the selected gene context region unrelated to any object in RegulonDB

	Type	Name	Post Left	Post Right	Strand	Notes	Evidence (Confirmed, Strong, Weak)	References
	promoter	TSS_2046	1819793		reverse	nd	[RS-EPT-CBR]	[1]

Evidence
[RS-EPT-CBR] RNA-seq using two enrichment strategies for primary transcripts and consistent biological replicates

Reference(s)
[1] Salgado H, Peralta-Gil M, Gama-Castro S, Santos-Zavaleta A, Muñiz-Rascado L, García-Sotelo JS, Weiss V, Solano-Lira H, Martínez-Flores I, Medina-Rivera A, Salgado-Osorio G, Alquicira-Hernández S, Alquicira-Hernández K, López-Fuentes A, Porrón-Sotelo L, Huerta AM, Bonavides-Martínez C, Balderas-Martínez YI, Pannier L, Olvera M, Labastida A, Jiménez-Jacinto V, Vega-Alvarado L, Del Moral-Chávez V, Hernández-Alvarez A, Morett E, Collado-Vides J., 2012, RegulonDB v8.0: omics data sets, evolutionary conservation, regulatory phrases, cross-validated gold standards and more., Nucleic Acids Res.

Reference(s)

[1] Salgado H, Peralta-Gil M, Gama-Castro S, Santos-Zavaleta A, Muñiz-Rascado L, García-Sotelo JS, Weiss V, Solano-Lira H, Martínez-Flores I, Medina-Rivera A, Salgado-Osorio G, Alquicira-Hernández S, Alquicira-Hernández K, López-Fuentes A, Porrón-Sotelo L, Huerta AM, Bonavides-Martínez C, Balderas-Martínez YI, Pannier L, Olvera M, Labastida A, Jiménez-Jacinto V, Vega-Alvarado L, Del Moral-Chávez V, Hernández-Alvarez A, Morett E, Collado-Vides J., 2012, RegulonDB v8.0: omics data sets, evolutionary conservation, regulatory phrases, cross-validated gold standards and more., Nucleic Acids Res.