RegulonDB RegulonDB 11.1: Gene Form
   

creD gene in Escherichia coli K-12 genome


Gene local context to scale (view description)

creC creD arcA CreB terminator TSS_5187 TSS_5187 creDp creDp

Gene      
Name: creD    Texpresso search in the literature
Synonym(s): ECK4392, EG10145, b4400, cet, refII
Genome position(nucleotides): 4638178 --> 4639530
Strand: forward
Sequence: Get nucleotide sequence FastaFormat
GC content %:  
 49.59
External database links:  
ASAP:
 ABE-0014432
CGSC:
 929
ECHOBASE:
 EB0143
ECOLIHUB:
 creD
OU-MICROARRAY:
 b4400
STRING:
 511145.b4400
COLOMBOS: creD


Shine dalgarno      
Sequence: gccattgcaaAGGAGAagactATG


Product      
Name: putative inner membrane protein CreD
Synonym(s): Cet, CreD
Sequence: Get amino acid sequence Fasta Format
Cellular location: inner membrane
Molecular weight: 49.83
Isoelectric point: 5.448
Motif(s):
 
Type Positions Sequence Comment
6 -> 427 LFWKMTSLFGAVLLLLIPIMLIRQVIVERADYRSDVEDAIRQSTSGPQKLVGPLIAIPVTELYTVQEEDKTVERKRSFIHFWLPESLMVDGNQNVEERKIGIYTGQVWHSDLTLKADFDVSRLSELNAPNITLGKPFIVISVGDARGIGVVKAPEVNGTALTIEPGTGLEQGGQGVHIPLPEGDWRKQNLKLNMALNLSGTGDLSVVPGGRNSEMTLTSNWPHPSFLGDFLPAKREVSESGFQAHWQSSWFANNLGERFASGNDTGWENFPAFSVAVTTPADQYQLTDRATKYAILLIALTFMAFFVFETLTAQRLHPMQYLLVGLSLVMFYLLLLALSEHTGFTVAWIIASLIGAIMNGIYLQAVLKGWCNSMLFTLALLLLDGVMWGLLNSADSALLLGTSVLVVALAGMMFVTRNIDWY
7 -> 27 FWKMTSLFGAVLLLLIPIMLI UniProt: Helical.
298 -> 318 YAILLIALTFMAFFVFETLTA UniProt: Helical.
323 -> 343 PMQYLLVGLSLVMFYLLLLAL UniProt: Helical.
348 -> 368 GFTVAWIIASLIGAIMNGIYL UniProt: Helical.

 
Classification:
Multifun Terms (GenProtEC)  
  6 - cell structure --> 6.1 - membrane
Gene Ontology Terms (GO)  
cellular_component GO:0016020 - membrane
GO:0005886 - plasma membrane
GO:0016021 - integral component of membrane
Note(s): Note(s): ...[more].
External database links:  
ALPHAFOLD:
 P08369
ECOCYC:
 EG10145-MONOMER
ECOLIWIKI:
 b4400
INTERPRO:
 IPR010364
PANTHER:
 PTHR30092
PFAM:
 PF06123
PRIDE:
 P08369
PRODB:
 PRO_000022331
REFSEQ:
 NP_418817
SMR:
 P08369
UNIPROT:
 P08369


Operon      
Name: creABCD         
Operon arrangement:
Transcription unit        Promoter
creABC
creABCD
creD


Transcriptional Regulation      
Display Regulation             
Activated by: CreB
Repressed by: NagC


RNA cis-regulatory element    
Attenuation: Translational


Elements in the selected gene context region unrelated to any object in RegulonDB      

  Type Name Post Left Post Right Strand Notes Evidence (Confirmed, Strong, Weak) References
  promoter TSS_5187 4640243 reverse nd [RS-EPT-CBR] [1]


Evidence    

 [RS-EPT-CBR] RNA-seq using two enrichment strategies for primary transcripts and consistent biological replicates


Reference(s)    

 [1] Salgado H, Peralta-Gil M, Gama-Castro S, Santos-Zavaleta A, Muñiz-Rascado L, García-Sotelo JS, Weiss V, Solano-Lira H, Martínez-Flores I, Medina-Rivera A, Salgado-Osorio G, Alquicira-Hernández S, Alquicira-Hernández K, López-Fuentes A, Porrón-Sotelo L, Huerta AM, Bonavides-Martínez C, Balderas-Martínez YI, Pannier L, Olvera M, Labastida A, Jiménez-Jacinto V, Vega-Alvarado L, Del Moral-Chávez V, Hernández-Alvarez A, Morett E, Collado-Vides J., 2012, RegulonDB v8.0: omics data sets, evolutionary conservation, regulatory phrases, cross-validated gold standards and more., Nucleic Acids Res.

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