RegulonDB RegulonDB 10.9: Gene Form
   

cysE gene in Escherichia coli K-12 genome


Gene local context to scale (view description)

gpsA cysE trmL RyhB TSS_4185 TSS_4185 TSS_4184 TSS_4184 TSS_4183 (cluster) TSS_4183 (cluster) cysEp cysEp

Gene      
Name: cysE    Texpresso search in the literature
Synonym(s): ECK3597, EG10187, b3607
Genome position(nucleotides): 3781741 <-- 3782562 Genome Browser
Strand: reverse
Sequence: Get nucleotide sequence FastaFormat
GC content %:  
53.53
External database links:  
ASAP:
ABE-0011793
CGSC:
894
ECHOBASE:
EB0184
ECOLIHUB:
cysE
OU-MICROARRAY:
b3607
STRING:
511145.b3607
COLOMBOS: cysE


Product      
Name: serine acetyltransferase
Synonym(s): CysE
Sequence: Get amino acid sequence Fasta Format
Cellular location: cytosol
Molecular weight: 29.317
Isoelectric point: 6.504
Motif(s):
 
Type Positions Sequence
193 -> 226 HPKIREGVMIGAGAKILGNIEVGRGAKIGAGSVV
9 -> 113 VWNNIKAEARTLADCEPMLASFYHATLLKHENLGSALSYMLANKLSSPIMPAIAIREVVEEAYAADPEMIASAACDIQAVRTRDPAVDKYSTPLLYLKGFHALQA

 

Classification:
Multifun Terms (GenProtEC)  
  1 - metabolism --> 1.5 - biosynthesis of building blocks --> 1.5.1 - amino acids --> 1.5.1.12 - cysteine
Gene Ontology Terms (GO)  
cellular_component GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0009333 - cysteine synthase complex
molecular_function GO:0005515 - protein binding
GO:0016740 - transferase activity
GO:0016746 - transferase activity, transferring acyl groups
GO:0009001 - serine O-acetyltransferase activity
GO:0016412 - serine O-acyltransferase activity
biological_process GO:0010165 - response to X-ray
GO:0008652 - cellular amino acid biosynthetic process
GO:0019344 - cysteine biosynthetic process
GO:0006535 - cysteine biosynthetic process from serine
External database links:  
DIP:
DIP-9377N
ECOCYC:
SERINE-O-ACETTRAN-MONOMER
ECOLIWIKI:
b3607
INTERPRO:
IPR001451
INTERPRO:
IPR042122
INTERPRO:
IPR005881
INTERPRO:
IPR010493
INTERPRO:
IPR011004
INTERPRO:
IPR018357
MODBASE:
P0A9D4
PDB:
1T3D
PFAM:
PF06426
PFAM:
PF00132
PRIDE:
P0A9D4
PRODB:
PRO_000022377
PROSITE:
PS00101
REFSEQ:
NP_418064
SMART:
SM00971
SMR:
P0A9D4
UNIPROT:
P0A9D4


Operon      
Name: cysE         
Operon arrangement:
Transcription unit        Promoter
cysE


Transcriptional Regulation      
Display Regulation             
Repressed by: SutR


Elements in the selected gene context region unrelated to any object in RegulonDB      

  Type Name Post Left Post Right Strand Notes Evidence (Confirmed, Strong, Weak) References
  promoter TSS_4183 (cluster) 3783637 reverse For this promoter, there
Read more >
[RS-EPT-CBR] [1]
  promoter TSS_4184 3783640 reverse nd [RS-EPT-CBR] [1]
  promoter TSS_4185 3783644 reverse nd [RS-EPT-CBR] [1]


Evidence    

 [RS-EPT-CBR] RNA-seq using two enrichment strategies for primary transcripts and consistent biological replicates



Reference(s)    

 [1] Salgado H, Peralta-Gil M, Gama-Castro S, Santos-Zavaleta A, Muñiz-Rascado L, García-Sotelo JS, Weiss V, Solano-Lira H, Martínez-Flores I, Medina-Rivera A, Salgado-Osorio G, Alquicira-Hernández S, Alquicira-Hernández K, López-Fuentes A, Porrón-Sotelo L, Huerta AM, Bonavides-Martínez C, Balderas-Martínez YI, Pannier L, Olvera M, Labastida A, Jiménez-Jacinto V, Vega-Alvarado L, Del Moral-Chávez V, Hernández-Alvarez A, Morett E, Collado-Vides J., 2012, RegulonDB v8.0: omics data sets, evolutionary conservation, regulatory phrases, cross-validated gold standards and more., Nucleic Acids Res.


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