RegulonDB RegulonDB 10.8: Gene Form
   

cysH gene in Escherichia coli K-12 genome


Gene local context to scale (view description)

cysI cysH sokX anti-terminator terminator TSS_3049 TSS_3049 TSS_3048 (cluster) TSS_3048 (cluster) TSS_3047 TSS_3047 TSS_3046 (cluster) TSS_3046 (cluster) TSS_3045 TSS_3045 TSS_3044 TSS_3044

Gene      
Name: cysH    Texpresso search in the literature
Synonym(s): ECK2757, EG10189, b2762
Genome position(nucleotides): 2887578 <-- 2888312 Genome Browser
Strand: reverse
Sequence: Get nucleotide sequence FastaFormat
GC content %:  
50.75
External database links:  
ASAP:
ABE-0009057
CGSC:
892
ECHOBASE:
EB0186
OU-MICROARRAY:
b2762
PortEco:
cysH
STRING:
511145.b2762
COLOMBOS: cysH


Product      
Name: phosphoadenosine phosphosulfate reductase
Synonym(s): CysH
Sequence: Get amino acid sequence Fasta Format
Cellular location: cytosol
Molecular weight: 27.976
Isoelectric point: 5.436
Motif(s):
 
Type Positions Sequence
239 -> 239 C
48 -> 219 YVLSSSFGIQAAVSLHLVNQIRPDIPVILTDTGYLFPETYRFIDELTDKLKLNLKVYRATESAAWQEARYGKLWEQGVEGIEKYNDINKVEPMNRALKELNAQTWFAGLRREQSGSRANLPVLAIQRGVFKVLPIIDWDNRTIYQYLQKHGLKYHPLWDEGYLSVGDTHTTR
209 -> 209 Y
2 -> 244 SKLDLNALNELPKVDRILALAETNAELEKLDAEGRVAWALDNLPGEYVLSSSFGIQAAVSLHLVNQIRPDIPVILTDTGYLFPETYRFIDELTDKLKLNLKVYRATESAAWQEARYGKLWEQGVEGIEKYNDINKVEPMNRALKELNAQTWFAGLRREQSGSRANLPVLAIQRGVFKVLPIIDWDNRTIYQYLQKHGLKYHPLWDEGYLSVGDTHTTRKWEPGMAEEETRFFGLKRECGLHEG
27 -> 27 E

 

Classification:
Multifun Terms (GenProtEC)  
  1 - metabolism --> 1.8 - metabolism of other compounds --> 1.8.2 - sulfur metabolism
Gene Ontology Terms (GO)  
cellular_component GO:0005737 - cytoplasm
GO:0005829 - cytosol
molecular_function GO:0003824 - catalytic activity
GO:0016491 - oxidoreductase activity
GO:0004604 - phosphoadenylyl-sulfate reductase (thioredoxin) activity
biological_process GO:0006790 - sulfur compound metabolic process
GO:0019379 - sulfate assimilation, phosphoadenylyl sulfate reduction by phosphoadenylyl-sulfate reductase (thioredoxin)
GO:0055114 - oxidation-reduction process
GO:0070814 - hydrogen sulfide biosynthetic process
External database links:  
ECOCYC:
PAPSSULFOTRANS-MONOMER
ECOLIWIKI:
b2762
INTERPRO:
IPR004511
INTERPRO:
IPR014729
INTERPRO:
IPR011800
INTERPRO:
IPR002500
MODBASE:
P17854
PDB:
1SUR
PDB:
2O8V
PFAM:
PF01507
PRIDE:
P17854
PRODB:
PRO_000022379
REFSEQ:
NP_417242
SMR:
P17854
UNIPROT:
P17854


Operon      
Name: cysJIH         
Operon arrangement:
Transcription unit        Promoter
cysJIH
cysH


Transcriptional Regulation      
Display Regulation             
Activated by: CysB, IHF, HypT


Elements in the selected gene context region unrelated to any object in RegulonDB      

  Type Name Post Left Post Right Strand Notes Evidence (Confirmed, Strong, Weak) References
  promoter TSS_3044 2888303 reverse nd [RS-EPT-CBR] [1]
  promoter TSS_3045 2888316 reverse nd [RS-EPT-CBR] [1]
  promoter TSS_3046 (cluster) 2888497 reverse For this promoter, there
Read more >
[RS-EPT-CBR] [1]
  promoter TSS_3047 2888501 reverse nd [RS-EPT-CBR] [1]
  promoter TSS_3048 (cluster) 2889307 reverse For this promoter, there
Read more >
[RS-EPT-CBR] [1]
  promoter TSS_3049 2889320 reverse nd [RS-EPT-CBR] [1]


Evidence    

 [RS-EPT-CBR] RNA-seq using two enrichment strategies for primary transcripts and consistent biological replicates



Reference(s)    

 [1] Salgado H, Peralta-Gil M, Gama-Castro S, Santos-Zavaleta A, Muñiz-Rascado L, García-Sotelo JS, Weiss V, Solano-Lira H, Martínez-Flores I, Medina-Rivera A, Salgado-Osorio G, Alquicira-Hernández S, Alquicira-Hernández K, López-Fuentes A, Porrón-Sotelo L, Huerta AM, Bonavides-Martínez C, Balderas-Martínez YI, Pannier L, Olvera M, Labastida A, Jiménez-Jacinto V, Vega-Alvarado L, Del Moral-Chávez V, Hernández-Alvarez A, Morett E, Collado-Vides J., 2012, RegulonDB v8.0: omics data sets, evolutionary conservation, regulatory phrases, cross-validated gold standards and more., Nucleic Acids Res.


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