Gene
Name:	dksA
Synonym(s):	ECK0144, EG10230, b0145, msmA
Genome position(nucleotides):	160149 <-- 160604 Genome Browser
Strand:	reverse
Sequence:	Get nucleotide sequence FastaFormat
GC content %:	52.63
External database links:

ASAP:	ABE-0000499
CGSC:	30521
ECHOBASE:	EB0226
ECOLIHUB:	dksA
OU-MICROARRAY:	b0145
STRING:	511145.b0145
COLOMBOS:	dksA

Type	Name	Post Left	Strand	Notes	Evidence (Confirmed, Strong, Weak)	References
promoter	gluQp1	160143	reverse	Similarity to the consensus sequence of the set of known functional promoters for this sigma factor with strong experimental evidence: poor homology. Score: -1.21. P-value: 1.354e-5 Read more >	[ICWHO]	[2]
promoter	TSS_274	160641	reverse	nd	[RS-EPT-CBR]	[3]
promoter	TSS_275 (cluster)	160652	reverse	For this promoter, there is a cluster of 2 transcription start sites,in the interval 160651 to 160652, where the highest frequency is at position 160651. The most upstream position of this cluster is assigned as TSS position in the promoter. Read more >	[RS-EPT-CBR]	[3]
promoter	TSS_277 (cluster)	160761	reverse	For this promoter, there is a cluster of 2 transcription start sites,in the interval 160760 to 160761, where the highest frequency is at position 160760. The most upstream position of this cluster is assigned as TSS position in the promoter. Read more >	[RS-EPT-CBR]	[3]
promoter	TSS_278	160873	reverse	nd	[RS-EPT-CBR]	[3]
promoter	TSS_279	160884	reverse	nd	[RS-EPT-CBR]	[3]
promoter	TSS_280	161071	reverse	nd	[RS-EPT-CBR]	[3]
promoter	TSS_281 (cluster)	161079	reverse	For this promoter, there is a cluster of 2 transcription start sites,in the interval 161078 to 161079, where the highest frequency is at position 161079. The most upstream position of this cluster is assigned as TSS position in the promoter. Read more >	[RS-EPT-CBR]	[3]
promoter	TSS_282	161142	reverse	nd	[RS-EPT-CBR]	[3]
promoter	TSS_283	161187	reverse	nd	[RS-EPT-CBR]	[3]
promoter	TSS_284 (cluster)	161195	reverse	For this promoter, there is a cluster of 3 transcription start sites,in the interval 161193 to 161195, where the highest frequency is at position 161194. The most upstream position of this cluster is assigned as TSS position in the promoter. Read more >	[RS-EPT-CBR]	[3]
promoter	TSS_285	161199	reverse	nd	[RS-EPT-CBR]	[3]

Evidence
[ICWHO] Inferred computationally without human oversight
[RS-EPT-CBR] RNA-seq using two enrichment strategies for primary transcripts and consistent biological replicates

Reference(s)
[1] Brown L., Gentry D., Elliott T., Cashel M., 2002, DksA affects ppGpp induction of RpoS at a translational level., J Bacteriol 184(16):4455-65
[2] Huerta AM., Collado-Vides J., 2003, Sigma70 promoters in Escherichia coli: specific transcription in dense regions of overlapping promoter-like signals., J Mol Biol 333(2):261-78
[3] Salgado H, Peralta-Gil M, Gama-Castro S, Santos-Zavaleta A, Muñiz-Rascado L, García-Sotelo JS, Weiss V, Solano-Lira H, Martínez-Flores I, Medina-Rivera A, Salgado-Osorio G, Alquicira-Hernández S, Alquicira-Hernández K, López-Fuentes A, Porrón-Sotelo L, Huerta AM, Bonavides-Martínez C, Balderas-Martínez YI, Pannier L, Olvera M, Labastida A, Jiménez-Jacinto V, Vega-Alvarado L, Del Moral-Chávez V, Hernández-Alvarez A, Morett E, Collado-Vides J., 2012, RegulonDB v8.0: omics data sets, evolutionary conservation, regulatory phrases, cross-validated gold standards and more., Nucleic Acids Res.

Transcriptional Regulation
	Display Regulation
Activated by:	CRP