RegulonDB RegulonDB 11.0: Gene Form
   

entA gene in Escherichia coli K-12 genome


Gene local context to scale (view description)

entE entB entA entH entHp entHp

Gene      
Name: entA    Texpresso search in the literature
Synonym(s): ECK0589, EG10259, b0596
Genome position(nucleotides): 628551 --> 629297
Strand: forward
Sequence: Get nucleotide sequence FastaFormat
GC content %:  
 57.97
External database links:  
ASAP:
 ABE-0002054
CGSC:
 822
ECHOBASE:
 EB0255
ECOLIHUB:
 entA
OU-MICROARRAY:
 b0596
STRING:
 511145.b0596
COLOMBOS: entA


Product      
Name: 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase
Synonym(s): EntA
Sequence: Get amino acid sequence Fasta Format
Cellular location: cytosol
Molecular weight: 26.25
Isoelectric point: 4.736
Motif(s):
 
Type Positions Sequence Comment
9 -> 33 WVTGAGKGIGYATALAFVEAGAKVT UniProt: NAD.
12 -> 245 GAGKGIGYATALAFVEAGAKVTGFDQAFTQEQYPFATEVMDVADAAQVAQVCQRLLAETERLDALVNAAGILRMGATDQLSKEDWQQTFAVNVGGAFNLFQQTMNQFRRQRGGAIVTVASDAAHTPRIGMSAYGASKAALKSLALSVGLELAGSGVRCNVVSPGSTDTDMQRTLWVSDDAEEQRIRGFGEQFKLGIPLGKIARPQEIANTILFLASDLASHITLQDIVVDGGST

 
Classification:
Multifun Terms (GenProtEC)  
  1 - metabolism --> 1.5 - biosynthesis of building blocks --> 1.5.3 - cofactors, small molecule carriers --> 1.5.3.14 - enterochelin (enterobactin)
Gene Ontology Terms (GO)  
cellular_component GO:0005829 - cytosol
GO:0032991 - protein-containing complex
molecular_function GO:0005515 - protein binding
GO:0016491 - oxidoreductase activity
GO:0008667 - 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase activity
GO:0042802 - identical protein binding
biological_process GO:0009239 - enterobactin biosynthetic process
GO:0019290 - siderophore biosynthetic process
External database links:  
ALPHAFOLD:
 P15047
DIP:
 DIP-9511N
ECOCYC:
 ENTA-MONOMER
ECOLIWIKI:
 b0596
INTERPRO:
 IPR036291
INTERPRO:
 IPR003560
INTERPRO:
 IPR020904
INTERPRO:
 IPR002347
MODBASE:
 P15047
PDB:
 2FWM
PFAM:
 PF13561
PRIDE:
 P15047
PRINTS:
 PR01397
PRINTS:
 PR00080
PRODB:
 PRO_000022519
PROSITE:
 PS00061
REFSEQ:
 NP_415128
SMR:
 P15047
UNIPROT:
 P15047


Operon      
Name: entCEBAH         
Operon arrangement:
Transcription unit        Promoter
entCEBA-ybdB
entH


Transcriptional Regulation      
Display Regulation             
Activated by: CRP
Repressed by: Fur


Elements in the selected gene context region unrelated to any object in RegulonDB      

  Type Name Post Left Post Right Strand Notes Evidence (Confirmed, Strong, Weak) References



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