RegulonDB RegulonDB 10.9: Gene Form
   

fliM gene in Escherichia coli K-12 genome


Gene local context to scale (view description)

fliM fliL fliN fliO TSS_2270 TSS_2270

Gene      
Name: fliM    Texpresso search in the literature
Synonym(s): ECK1943, EG10323, b1945, cheC2, fla, flaA, flaAII, flaQ, flaQII
Genome position(nucleotides): 2020087 --> 2021091 Genome Browser
Strand: forward
Sequence: Get nucleotide sequence FastaFormat
GC content %:  
53.33
Reference(s): [1] Hou Z., et al., 2012
External database links:  
ASAP:
ABE-0006469
CGSC:
774
ECHOBASE:
EB0319
ECOLIHUB:
fliM
OU-MICROARRAY:
b1945
STRING:
511145.b1945
COLOMBOS: fliM


Product      
Name: flagellar motor switch protein FliM
Synonym(s): Fla, FlaA, FlaQ, FliM
Sequence: Get amino acid sequence Fasta Format
Cellular location: inner membrane,cell projection
Molecular weight: 37.849
Isoelectric point: 5.436
Motif(s):
 
Type Positions Sequence
153 -> 153 V
155 -> 155 N
167 -> 167 D
156 -> 156 R
160 -> 160 L

 

Classification:
Multifun Terms (GenProtEC)  
  1 - metabolism --> 1.6 - biosynthesis of macromolecules (cellular constituents) --> 1.6.12 - flagellum
  5 - cell processes --> 5.3 - motility, chemotaxis, energytaxis (aerotaxis, redoxtaxis etc)
  6 - cell structure --> 6.4 - flagella
Gene Ontology Terms (GO)  
cellular_component GO:0016020 - membrane
GO:0005886 - plasma membrane
GO:0009288 - bacterial-type flagellum
GO:0009425 - bacterial-type flagellum basal body
molecular_function GO:0005515 - protein binding
GO:0003774 - motor activity
biological_process GO:0006935 - chemotaxis
GO:0071973 - bacterial-type flagellum-dependent cell motility
GO:0050918 - positive chemotaxis
GO:0097588 - archaeal or bacterial-type flagellum-dependent cell motility
Note(s): Note(s): ...[more].
Reference(s): [2] Tang H., et al., 1995
External database links:  
DIP:
DIP-1100N
ECOCYC:
FLIM-FLAGELLAR-C-RING-SWITCH
ECOLIWIKI:
b1945
INTERPRO:
IPR028976
INTERPRO:
IPR001689
INTERPRO:
IPR001543
INTERPRO:
IPR036429
MINT:
P06974
MODBASE:
P06974
PDB:
2B1J
PDB:
1U8T
PDB:
1F4V
PFAM:
PF01052
PFAM:
PF02154
PRIDE:
P06974
PRINTS:
PR00955
PRODB:
PRO_000022664
REFSEQ:
NP_416455
SMR:
P06974
UNIPROT:
P06974


Operon      
Name: fliLMNOPQR         
Operon arrangement:
Transcription unit        Promoter
fliLMNOPQR
fliLMNOPQR


Transcriptional Regulation      
Display Regulation             
Activated by: FlhDC


Elements in the selected gene context region unrelated to any object in RegulonDB      

  Type Name Post Left Post Right Strand Notes Evidence (Confirmed, Strong, Weak) References
  promoter TSS_2270 2020910 forward nd [RS-EPT-CBR] [3]


Evidence    

 [RS-EPT-CBR] RNA-seq using two enrichment strategies for primary transcripts and consistent biological replicates



Reference(s)    

 [1] Hou Z., Fink RC., Black EP., Sugawara M., Zhang Z., Diez-Gonzalez F., Sadowsky MJ., 2012, Gene expression profiling of Escherichia coli in response to interactions with the lettuce rhizosphere., J Appl Microbiol 113(5):1076-86

 [2] Tang H., Blair DF., 1995, Regulated underexpression of the FliM protein of Escherichia coli and evidence for a location in the flagellar motor distinct from the MotA/MotB torque generators., J Bacteriol 177(12):3485-95

 [3] Salgado H, Peralta-Gil M, Gama-Castro S, Santos-Zavaleta A, Muñiz-Rascado L, García-Sotelo JS, Weiss V, Solano-Lira H, Martínez-Flores I, Medina-Rivera A, Salgado-Osorio G, Alquicira-Hernández S, Alquicira-Hernández K, López-Fuentes A, Porrón-Sotelo L, Huerta AM, Bonavides-Martínez C, Balderas-Martínez YI, Pannier L, Olvera M, Labastida A, Jiménez-Jacinto V, Vega-Alvarado L, Del Moral-Chávez V, Hernández-Alvarez A, Morett E, Collado-Vides J., 2012, RegulonDB v8.0: omics data sets, evolutionary conservation, regulatory phrases, cross-validated gold standards and more., Nucleic Acids Res.


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