RegulonDB RegulonDB 11.1: Gene Form
   

fucA gene in Escherichia coli K-12 genome


Gene local context to scale (view description)

fucP fucO fucA CRP CRP Spot 42 Spot 42 terminator anti-terminator anti-anti-terminator anti-anti-terminator anti-terminator terminator fucPp fucPp fucAp fucAp fucOp fucOp

Gene      
Name: fucA    Texpresso search in the literature
Synonym(s): ECK2795, EG10348, b2800, fucC, prd
Genome position(nucleotides): 2933041 <-- 2933688
Strand: reverse
Sequence: Get nucleotide sequence FastaFormat
GC content %:  
 49.07
External database links:  
ASAP:
 ABE-0009179
CGSC:
 17701
ECHOBASE:
 EB0344
ECOLIHUB:
 fucA
OU-MICROARRAY:
 b2800
STRING:
 511145.b2800
COLOMBOS: fucA


Product      
Name: L-fuculose-phosphate aldolase
Synonym(s): FucA, FucC, Prd
Sequence: Get amino acid sequence Fasta Format
Cellular location: cytosol
Molecular weight: 23.775
Isoelectric point: 6.576
Motif(s):
 
Type Positions Sequence Comment
9 -> 182 QIIDTCLEMTRLGLNQGTAGNVSVRYQDGMLITPTGIPYEKLTESHIVFIDGNGKHEEGKLPSSEWRFHMAAYQSRPDANAVVHNHAVHCTAVSILNRSIPAIHYMIAAAGGNSIPCAPYATFGTRELSEHVALALKNRKATLLQHHGLIACEVNLEKALWLAHEVEVLAQLYL
26 -> 26 T UniProt: Decrease of the aldolase activity mostly due to a decrease of the affinity for L-fuculose 1-phosphate (Fuc1P)..
27 -> 27 A UniProt: Strong decrease of the aldolase activity..
28 -> 29 GN UniProt: Substrate binding; Sequence Annotation Type: region of interest.
29 -> 29 N UniProt: Strong decrease of the aldolase activity mostly due to a decrease of the affinity for L-fuculose 1-phosphate (Fuc1P)..

 
Classification:
Multifun Terms (GenProtEC)  
  1 - metabolism --> 1.1 - carbon utilization --> 1.1.1 - carbon compounds
Gene Ontology Terms (GO)  
cellular_component GO:0005829 - cytosol
molecular_function GO:0016829 - lyase activity
GO:0046872 - metal ion binding
GO:0016832 - aldehyde-lyase activity
GO:0008270 - zinc ion binding
GO:0008738 - L-fuculose-phosphate aldolase activity
biological_process GO:0005975 - carbohydrate metabolic process
GO:0019323 - pentose catabolic process
GO:0006004 - fucose metabolic process
GO:0019317 - fucose catabolic process
GO:0019568 - arabinose catabolic process
GO:0019571 - D-arabinose catabolic process
GO:0042355 - L-fucose catabolic process
Note(s): Note(s): ...[more].
External database links:  
ALPHAFOLD:
 P0AB87
DIP:
 DIP-9710N
ECOCYC:
 FUCPALDOL-MONOMER
ECOLIWIKI:
 b2800
INTERPRO:
 IPR001303
INTERPRO:
 IPR004782
INTERPRO:
 IPR036409
MODBASE:
 P0AB87
PDB:
 1E49
PDB:
 1E4A
PDB:
 1E4B
PDB:
 1E4C
PDB:
 1FUA
PDB:
 2FUA
PDB:
 3FUA
PDB:
 4FUA
PDB:
 1E48
PDB:
 1E47
PDB:
 1E46
PDB:
 1DZZ
PDB:
 1DZY
PDB:
 1DZX
PDB:
 1DZW
PDB:
 1DZU
PDB:
 1DZV
PFAM:
 PF00596
PRIDE:
 P0AB87
PRODB:
 PRO_000022727
REFSEQ:
 NP_417280
SMART:
 SM01007
SMR:
 P0AB87
UNIPROT:
 P0AB87


Operon      
Name: fucAO         
Operon arrangement:
Transcription unit        Promoter
fucO
fucAO


Transcriptional Regulation      
Display Regulation             
Activated by: CRP, FucR


RNA cis-regulatory element    
Attenuation: Transcriptional


Elements in the selected gene context region unrelated to any object in RegulonDB      

  Type Name Post Left Post Right Strand Notes Evidence (Confirmed, Strong, Weak) References



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