RegulonDB RegulonDB 10.8: Gene Form
   

fucP gene in Escherichia coli K-12 genome


Gene local context to scale (view description)

fucI fucP fucA CRP CRP terminator anti-terminator anti-anti-terminator anti-anti-terminator anti-terminator terminator fucPp fucPp fucAp fucAp fucOp fucOp

Gene      
Name: fucP    Texpresso search in the literature
Synonym(s): ECK2796, EG10352, b2801
Genome position(nucleotides): 2934235 --> 2935551 Genome Browser
Strand: forward
Sequence: Get nucleotide sequence FastaFormat
GC content %:  
 47.68
External database links:  
ASAP:
 ABE-0009187
CGSC:
 10875
ECHOBASE:
 EB0348
OU-MICROARRAY:
 b2801
PortEco:
 fucP
STRING:
 511145.b2801
COLOMBOS: fucP


Product      
Name: L-fucose:H+ symporter
Synonym(s): FucP, FucP fucose MFS transporter
Sequence: Get amino acid sequence Fasta Format
Cellular location: inner membrane
Molecular weight: 47.545
Isoelectric point: 8.829
Motif(s):
 
Type Positions Sequence
25 -> 45 IIPFALLCSLFFLWAVANNLN
167 -> 187 IIAVVFGQSLILSNVPHQSQD
353 -> 373 ALTLCSAFMSIQYPTIFSLGI
382 -> 402 YGSSFIVMTIIGGGIVTPVMG
414 -> 434 AELIPALCFAVIFIFARFRSQ

 
Classification:
Multifun Terms (GenProtEC)  
  1 - metabolism --> 1.1 - carbon utilization --> 1.1.1 - carbon compounds
  4 - transport --> 4.2 - Electrochemical potential driven transporters --> 4.2.A - Porters (Uni-, Sym- and Antiporters)
  6 - cell structure --> 6.1 - membrane
Gene Ontology Terms (GO)  
cellular_component GO:0016020 - membrane
GO:0005886 - plasma membrane
GO:0016021 - integral component of membrane
molecular_function GO:0015293 - symporter activity
GO:0009679 - hexose:proton symporter activity
GO:0015150 - fucose transmembrane transporter activity
GO:0015517 - galactose:proton symporter activity
GO:0015518 - arabinose:proton symporter activity
GO:0015535 - fucose:proton symporter activity
GO:0022857 - transmembrane transporter activity
biological_process GO:0005975 - carbohydrate metabolic process
GO:0008643 - carbohydrate transport
GO:0006004 - fucose metabolic process
GO:0015751 - arabinose transmembrane transport
GO:0015755 - fructose transmembrane transport
GO:0015756 - fucose transmembrane transport
GO:0015757 - galactose transmembrane transport
GO:0055085 - transmembrane transport
Note(s): Note(s): ...[more].
Reference(s): [1] Bartkus JM., et al., 1986
[2] Elsinghorst EA., et al., 1994
[3] Zhu Y., et al., 1988
External database links:  
ECOCYC:
 FUCP-MONOMER
ECOLIWIKI:
 b2801
INTERPRO:
 IPR005275
INTERPRO:
 IPR036259
INTERPRO:
 IPR020846
INTERPRO:
 IPR011701
MODBASE:
 P11551
PDB:
 3O7P
PDB:
 3O7Q
PFAM:
 PF07690
PRIDE:
 P11551
PRODB:
 PRO_000022731
PROSITE:
 PS50850
REFSEQ:
 NP_417281
SMR:
 P11551
UNIPROT:
 P11551


Operon      
Name: fucPIKUR         
Operon arrangement:
Transcription unit        Promoter
fucPIKUR
fucU
fucR


Transcriptional Regulation      
Display Regulation             
Activated by: CRP, FucR


RNA cis-regulatory element    
Attenuation: Transcriptional


Elements in the selected gene context region unrelated to any object in RegulonDB      

  Type Name Post Left Post Right Strand Notes Evidence (Confirmed, Strong, Weak) References


Reference(s)    

 [1] Bartkus JM., Mortlock RP., 1986, Isolation of a mutation resulting in constitutive synthesis of L-fucose catabolic enzymes., J Bacteriol 165(3):710-4

 [2] Elsinghorst EA., Mortlock RP., 1994, Molecular cloning of the Escherichia coli B L-fucose-D-arabinose gene cluster., J Bacteriol 176(23):7223-32

 [3] Zhu Y., Lin EC., 1988, A mutant crp allele that differentially activates the operons of the fuc regulon in Escherichia coli., J Bacteriol 170(5):2352-8

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