RegulonDB RegulonDB 11.1: Gene Form
   

livF gene in Escherichia coli K-12 genome


Gene local context to scale (view description)

ugpB livG livF livM PhoB CRP PhoB PhoB terminator ugpBp2 ugpBp2 ugpBp1 ugpBp1

Gene      
Name: livF    Texpresso search in the literature
Synonym(s): ECK3438, EG10536, b3454
Genome position(nucleotides): 3592724 <-- 3593437
Strand: reverse
Sequence: Get nucleotide sequence FastaFormat
GC content %:  
 56.72
External database links:  
ASAP:
 ABE-0011282
CGSC:
 33713
ECHOBASE:
 EB0531
ECOLIHUB:
 livF
OU-MICROARRAY:
 b3454
STRING:
 511145.b3454
COLOMBOS: livF


Product      
Name: branched chain amino acid/phenylalanine ABC transporter ATP binding subunit LivF
Synonym(s): LivF
Sequence: Get amino acid sequence Fasta Format
Cellular location: cytosol,inner membrane
Molecular weight: 26.31
Isoelectric point: 5.677
Motif(s):
 
Type Positions Sequence Comment
6 -> 237 LSFDKVSAHYGKIQALHEVSLHINQGEIVTLIGANGAGKTTLLGTLCGDPRATSGRIVFDDKDITDWQTAKIMREAVAIVPEGRRVFSRMTVEENLAMGGFFAERDQFQERIKWVYELFPRLHERRIQRAGTMSGGEQQMLAIGRALMSNPRLLLLDEPSLGLAPIIIQQIFDTIEQLREQGMTIFLVEQNANQALKLADRGYVLENGHVVLSDTGDALLANEAVRSAYLGG UniProt: ABC transporter.
21 -> 165 LHEVSLHINQGEIVTLIGANGAGKTTLLGTLCGDPRATSGRIVFDDKDITDWQTAKIMREAVAIVPEGRRVFSRMTVEENLAMGGFFAERDQFQERIKWVYELFPRLHERRIQRAGTMSGGEQQMLAIGRALMSNPRLLLLDEPS
38 -> 45 GANGAGKT UniProt: ATP.
56 -> 56 R UniProt: In Ref. 1; AAA83887..
120 -> 120 V UniProt: In Ref. 1; AAA83887..

 
Classification:
Multifun Terms (GenProtEC)  
  1 - metabolism --> 1.1 - carbon utilization --> 1.1.3 - amino acids
  1 - metabolism --> 1.5 - biosynthesis of building blocks --> 1.5.1 - amino acids --> 1.5.1.13 - phenylalanine
  1 - metabolism --> 1.5 - biosynthesis of building blocks --> 1.5.1 - amino acids --> 1.5.1.18 - isoleucine/valine
  1 - metabolism --> 1.5 - biosynthesis of building blocks --> 1.5.1 - amino acids --> 1.5.1.19 - leucine
  4 - transport --> 4.3 - Primary Active Transporters --> 4.3.A - Pyrophosphate Bond (ATP; GTP; P2) Hydrolysis-driven Active Transporters --> 4.3.A.1 - The ATP-binding Cassette (ABC) Superfamily + ABC-type Uptake Permeases --> 4.3.A.1.a - ABC superfamily ATP binding cytoplasmic component
Gene Ontology Terms (GO)  
cellular_component GO:0005829 - cytosol
GO:0016020 - membrane
GO:0005886 - plasma membrane
GO:0055052 - ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing
molecular_function GO:0000166 - nucleotide binding
GO:0005524 - ATP binding
GO:0015658 - branched-chain amino acid transmembrane transporter activity
GO:0005304 - L-valine transmembrane transporter activity
GO:0015190 - L-leucine transmembrane transporter activity
GO:0015188 - L-isoleucine transmembrane transporter activity
biological_process GO:0006865 - amino acid transport
GO:0015807 - L-amino acid transport
GO:0015803 - branched-chain amino acid transport
GO:0015823 - phenylalanine transport
GO:1903714 - isoleucine transmembrane transport
GO:1903785 - L-valine transmembrane transport
GO:0098713 - leucine import across plasma membrane
Note(s): Note(s): ...[more].
External database links:  
ALPHAFOLD:
 P22731
ECOCYC:
 LIVF-MONOMER
ECOLIWIKI:
 b3454
INTERPRO:
 IPR003439
INTERPRO:
 IPR030660
INTERPRO:
 IPR017871
INTERPRO:
 IPR027417
INTERPRO:
 IPR003593
MODBASE:
 P22731
PFAM:
 PF00005
PRIDE:
 P22731
PRODB:
 PRO_000023094
PROSITE:
 PS50893
PROSITE:
 PS00211
REFSEQ:
 NP_417911
SMART:
 SM00382
SMR:
 P22731
SWISSMODEL:
 P22731
UNIPROT:
 P22731


Operon      
Name: livKHMGF         
Operon arrangement:
Transcription unit        Promoter
livKHMGF
livKHMGF


Transcriptional Regulation      
Display Regulation             
Repressed by: Lrp


Elements in the selected gene context region unrelated to any object in RegulonDB      

  Type Name Post Left Post Right Strand Notes Evidence (Confirmed, Strong, Weak) References



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