RegulonDB RegulonDB 10.9: Gene Form
   

livH gene in Escherichia coli K-12 genome


Gene local context to scale (view description)

livM livK livH livG TSS_4058 TSS_4058

Gene      
Name: livH    Texpresso search in the literature
Synonym(s): ECK3441, EG10538, b3457, hrbB, hrbC, hrbD
Genome position(nucleotides): 3595477 <-- 3596403 Genome Browser
Strand: reverse
Sequence: Get nucleotide sequence FastaFormat
GC content %:  
56.2
External database links:  
ASAP:
ABE-0011290
CGSC:
552
ECHOBASE:
EB0533
ECOLIHUB:
livH
OU-MICROARRAY:
b3457
STRING:
511145.b3457
COLOMBOS: livH


Shine dalgarno      
Sequence: gggcgggtttAGAAAGgttacctTAT


Product      
Name: branched chain amino acid/phenylalanine ABC transporter membrane subunit LivH
Synonym(s): HrbB, HrbC, HrbD, LivH
Sequence: Get amino acid sequence Fasta Format
Cellular location: inner membrane
Molecular weight: 32.982
Isoelectric point: 8.156
Motif(s):
 
Type Positions Sequence
22 -> 42 YALIAIGYTMVYGIIGMINFA
204 -> 224 VIALTFVIGAAMAAVAGVLLG
253 -> 253 S
288 -> 288 L
12 -> 292 MFNGVTLGSTYALIAIGYTMVYGIIGMINFAHGEVYMIGSYVSFMIIAALMMMGIDTGWLLVAAGFVGAIVIASAYGWSIERVAYRPVRNSKRLIALISAIGMSIFLQNYVSLTEGSRDVALPSLFNGQWVVGHSENFSASITTMQAVIWIVTFLAMLALTIFIRYSRMGRACRACAEDLKMASLLGINTDRVIALTFVIGAAMAAVAGVLLGQFYGVINPYIGFMAGMKAFTAAVLGGIGSIPGAMIGGLILGIAEALSSAYLSTEYKDVVSFALLILVL

 

Classification:
Multifun Terms (GenProtEC)  
  1 - metabolism --> 1.5 - biosynthesis of building blocks --> 1.5.1 - amino acids --> 1.5.1.18 - isoleucine/valine
  1 - metabolism --> 1.5 - biosynthesis of building blocks --> 1.5.1 - amino acids --> 1.5.1.19 - leucine
  6 - cell structure --> 6.1 - membrane
  4 - transport --> 4.3 - Primary Active Transporters --> 4.3.A - Pyrophosphate Bond (ATP; GTP; P2) Hydrolysis-driven Active Transporters --> 4.3.A.1 - The ATP-binding Cassette (ABC) Superfamily + ABC-type Uptake Permeases --> 4.3.A.1.m - ABC superfamily, membrane component
Gene Ontology Terms (GO)  
cellular_component GO:0016020 - membrane
GO:0005886 - plasma membrane
GO:0005887 - integral component of plasma membrane
GO:0016021 - integral component of membrane
GO:0055052 - ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing
molecular_function GO:0022857 - transmembrane transporter activity
GO:0015192 - L-phenylalanine transmembrane transporter activity
GO:0015658 - branched-chain amino acid transmembrane transporter activity
GO:0005304 - L-valine transmembrane transporter activity
GO:0015190 - L-leucine transmembrane transporter activity
GO:0015188 - L-isoleucine transmembrane transporter activity
biological_process GO:1903806 - L-isoleucine import across plasma membrane
GO:0006865 - amino acid transport
GO:0015803 - branched-chain amino acid transport
GO:0015823 - phenylalanine transport
GO:0055085 - transmembrane transport
GO:0015808 - L-alanine transport
GO:0042941 - D-alanine transport
GO:1903714 - isoleucine transmembrane transport
GO:1903785 - L-valine transmembrane transport
GO:0098713 - leucine import across plasma membrane
Note(s): Note(s): ...[more].
External database links:  
ECOCYC:
LIVH-MONOMER
ECOLIWIKI:
b3457
INTERPRO:
IPR001851
PFAM:
PF02653
PRIDE:
P0AEX7
PRODB:
PRO_000023096
REFSEQ:
NP_417914
UNIPROT:
P0AEX7


Operon      
Name: livKHMGF         
Operon arrangement:
Transcription unit        Promoter
livKHMGF
livKHMGF


Transcriptional Regulation      
Display Regulation             
Repressed by: Lrp


Elements in the selected gene context region unrelated to any object in RegulonDB      

  Type Name Post Left Post Right Strand Notes Evidence (Confirmed, Strong, Weak) References
  promoter TSS_4058 3596577 reverse nd [RS-EPT-CBR] [1]


Evidence    

 [RS-EPT-CBR] RNA-seq using two enrichment strategies for primary transcripts and consistent biological replicates



Reference(s)    

 [1] Salgado H, Peralta-Gil M, Gama-Castro S, Santos-Zavaleta A, Muñiz-Rascado L, García-Sotelo JS, Weiss V, Solano-Lira H, Martínez-Flores I, Medina-Rivera A, Salgado-Osorio G, Alquicira-Hernández S, Alquicira-Hernández K, López-Fuentes A, Porrón-Sotelo L, Huerta AM, Bonavides-Martínez C, Balderas-Martínez YI, Pannier L, Olvera M, Labastida A, Jiménez-Jacinto V, Vega-Alvarado L, Del Moral-Chávez V, Hernández-Alvarez A, Morett E, Collado-Vides J., 2012, RegulonDB v8.0: omics data sets, evolutionary conservation, regulatory phrases, cross-validated gold standards and more., Nucleic Acids Res.


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