RegulonDB

Gene
Name:	mglA
Synonym(s):	ECK2142, EG10592, b2149, mgl, mglP
Genome position(nucleotides):	2237769 <-- 2239289 Genome Browser
Strand:	reverse
Sequence:	Get nucleotide sequence FastaFormat
GC content %:	45.36
External database links:

ASAP:	ABE-0007103
CGSC:	502
ECHOBASE:	EB0587
ECOLIHUB:	mglA
OU-MICROARRAY:	b2149
STRING:	511145.b2149
COLOMBOS:	mglA

Product

Name:

D-galactose/methyl-galactoside ABC transporter ATP binding subunit

Synonym(s):

Mgl, MglA, MglP

Sequence:

Get amino acid sequence Fasta Format

Cellular location:

inner membrane

Molecular weight:

56.415

Isoelectric point:

7.746

Motif(s):

Type	Positions	Sequence
	14 -> 249	LEMSGINKSFPGVKALDNVNLKVRPHSIHALMGENGAGKSTLLKCLFGIYQKDSGTILFQGKEIDFHSAKEALENGISMVHQELNLVLQRSVMDNMWLGRYPTKGMFVDQDKMYRETKAIFDELDIDIDPRARVGTLSVSQMQMIEIAKAFSYNAKIVIMDEPTSSLTEKEVNHLFTIIRKLKERGCGIVYISHKMEEIFQLCDEVTVLRDGQWIATEPLAGLTMDKIIAMMVGRS
	29 -> 178	LDNVNLKVRPHSIHALMGENGAGKSTLLKCLFGIYQKDSGTILFQGKEIDFHSAKEALENGISMVHQELNLVLQRSVMDNMWLGRYPTKGMFVDQDKMYRETKAIFDELDIDIDPRARVGTLSVSQMQMIEIAKAFSYNAKIVIMDEPTS
	46 -> 53	GENGAGKS
	170 -> 177	IVIMDEPT
	407 -> 410	LSGG

Classification:

Multifun Terms (GenProtEC)
		1 - metabolism --> 1.1 - carbon utilization --> 1.1.1 - carbon compounds
		4 - transport --> 4.3 - Primary Active Transporters --> 4.3.A - Pyrophosphate Bond (ATP; GTP; P2) Hydrolysis-driven Active Transporters --> 4.3.A.1 - The ATP-binding Cassette (ABC) Superfamily + ABC-type Uptake Permeases --> 4.3.A.1.a - ABC superfamily ATP binding cytoplasmic component
Gene Ontology Terms (GO)
	cellular_component	GO:0016020 - membrane GO:0005886 - plasma membrane GO:0043190 - ATP-binding cassette (ABC) transporter complex
	molecular_function	GO:0016887 - ATP hydrolysis activity GO:0000166 - nucleotide binding GO:0005524 - ATP binding GO:0005354 - galactose transmembrane transporter activity GO:0015407 - ABC-type monosaccharide transporter activity GO:0043211 - ABC-type carbohydrate transporter activity GO:0015592 - methylgalactoside transmembrane transporter activity
	biological_process	GO:0006974 - cellular response to DNA damage stimulus GO:0008643 - carbohydrate transport GO:0015757 - galactose transmembrane transport GO:0015765 - methylgalactoside transport

Note(s):

Note(s): ...[more].

External database links:

ECOCYC:

ECOLIWIKI:

INTERPRO:

INTERPRO:

INTERPRO:

INTERPRO:

INTERPRO:

MODBASE:

PANTHER:

PFAM:

PRIDE:

PRODB:

PROSITE:

PROSITE:

PROSITE:

REFSEQ:

SMART:

UNIPROT:

Transcriptional Regulation
	Display Regulation
Activated by:	CRP
Repressed by:	GalS, FlhDC, GalR, Fis

Elements in the selected gene context region unrelated to any object in RegulonDB

Type	Name	Post Left	Strand	Notes	Evidence (Confirmed, Strong, Weak)	References
promoter	mglCp5	2237858	reverse	nd	[ICWHO]	[1]
promoter	mglCp9	2237923	reverse	Similarity to the consensus sequence of the set of known functional promoters for this sigma factor with strong experimental evidence: good homology. Score: 4.45. P-value: 2.254e-5 It was suggested that this predicted promoter does not exist, because its activity was not observed during σE induction in high-throughput analysis Lacoux C,2020. Read more >	[ICWHO]	[1]
promoter	mglCp6	2237959	reverse	Similarity to the consensus sequence of the set of known functional promoters for this sigma factor with strong experimental evidence: good homology. Score: 2.99. P-value: 8.028e-5 It was suggested that this predicted promoter does not exist, because its activity was not observed during σE induction in high-throughput analysis Lacoux C,2020. Read more >	[ICWHO]	[1]