RegulonDB

Gene
Name:	mglA
Synonym(s):	ECK2142, EG10592, b2149, mgl, mglP
Genome position(nucleotides):	2237769 <-- 2239289 Genome Browser
Strand:	reverse
Sequence:	Get nucleotide sequence FastaFormat
GC content %:	45.36
External database links:

ASAP:	ABE-0007103
CGSC:	502
ECHOBASE:	EB0587
ECOLIHUB:	mglA
OU-MICROARRAY:	b2149
STRING:	511145.b2149
COLOMBOS:	mglA

Product

Name:

D-galactose/methyl-galactoside ABC transporter ATP binding subunit

Synonym(s):

Mgl, MglA, MglP

Sequence:

Get amino acid sequence Fasta Format

Cellular location:

inner membrane

Molecular weight:

56.415

Isoelectric point:

7.746

Motif(s):

Type	Positions	Sequence
	14 -> 249	LEMSGINKSFPGVKALDNVNLKVRPHSIHALMGENGAGKSTLLKCLFGIYQKDSGTILFQGKEIDFHSAKEALENGISMVHQELNLVLQRSVMDNMWLGRYPTKGMFVDQDKMYRETKAIFDELDIDIDPRARVGTLSVSQMQMIEIAKAFSYNAKIVIMDEPTSSLTEKEVNHLFTIIRKLKERGCGIVYISHKMEEIFQLCDEVTVLRDGQWIATEPLAGLTMDKIIAMMVGRS
	29 -> 178	LDNVNLKVRPHSIHALMGENGAGKSTLLKCLFGIYQKDSGTILFQGKEIDFHSAKEALENGISMVHQELNLVLQRSVMDNMWLGRYPTKGMFVDQDKMYRETKAIFDELDIDIDPRARVGTLSVSQMQMIEIAKAFSYNAKIVIMDEPTS
	46 -> 53	GENGAGKS
	170 -> 177	IVIMDEPT
	407 -> 410	LSGG

Classification:

Multifun Terms (GenProtEC)
		1 - metabolism --> 1.1 - carbon utilization --> 1.1.1 - carbon compounds
		4 - transport --> 4.3 - Primary Active Transporters --> 4.3.A - Pyrophosphate Bond (ATP; GTP; P2) Hydrolysis-driven Active Transporters --> 4.3.A.1 - The ATP-binding Cassette (ABC) Superfamily + ABC-type Uptake Permeases --> 4.3.A.1.a - ABC superfamily ATP binding cytoplasmic component
Gene Ontology Terms (GO)
	cellular_component	GO:0016020 - membrane GO:0005886 - plasma membrane GO:0043190 - ATP-binding cassette (ABC) transporter complex
	molecular_function	GO:0016887 - ATPase activity GO:0000166 - nucleotide binding GO:0005524 - ATP binding GO:0005354 - galactose transmembrane transporter activity GO:0015407 - ATPase-coupled monosaccharide transmembrane transporter activity GO:0043211 - ATPase-coupled carbohydrate transmembrane transporter activity GO:0015592 - methylgalactoside transmembrane transporter activity
	biological_process	GO:0006974 - cellular response to DNA damage stimulus GO:0008643 - carbohydrate transport GO:0015757 - galactose transmembrane transport GO:0015765 - methylgalactoside transport

Note(s):

Note(s): ...[more].

External database links:

ECOCYC:

ECOLIWIKI:

INTERPRO:

INTERPRO:

INTERPRO:

INTERPRO:

INTERPRO:

MODBASE:

PANTHER:

PFAM:

PRIDE:

PRODB:

PROSITE:

PROSITE:

PROSITE:

REFSEQ:

SMART:

UNIPROT:

Transcriptional Regulation
	Display Regulation
Activated by:	CRP
Repressed by:	GalS, FlhDC, Fis, GalR

Elements in the selected gene context region unrelated to any object in RegulonDB

Type	Name	Post Left	Strand	Notes	Evidence (Confirmed, Strong, Weak)	References
promoter	mglCp5	2237858	reverse	Similarity to the consensus sequence of the set of known functional promoters for this sigma factor with strong experimental evidence: poor homology. Score: 2.985. P-value: 8.440e-5 Read more >	[ICWHO]	[1]
promoter	mglCp9	2237923	reverse	Similarity to the consensus sequence of the set of known functional promoters for this sigma factor with strong experimental evidence: good homology. Score: 4.45. P-value: 2.254e-5 It was suggested that this predicted promoter does not exist, because its activity was not observed during σE induction in high-throughput analysis Lacoux C,2020. Read more >	[ICWHO]	[1]
promoter	mglCp6	2237959	reverse	Similarity to the consensus sequence of the set of known functional promoters for this sigma factor with strong experimental evidence: good homology. Score: 2.99. P-value: 8.028e-5 It was suggested that this predicted promoter does not exist, because its activity was not observed during σE induction in high-throughput analysis Lacoux C,2020. Read more >	[ICWHO]	[1]