RegulonDB RegulonDB 10.10: Gene Form
   

osmB gene in Escherichia coli K-12 genome


Gene local context to scale (view description)

yciT yciH osmB RcsB osmBp1 osmBp1 TSS_1729 TSS_1729 osmBp2 osmBp2 TSS_1728 TSS_1728

Gene      
Name: osmB    Texpresso search in the literature
Synonym(s): ECK1278, EG10679, b1283
Genome position(nucleotides): 1343110 <-- 1343328 Genome Browser
Strand: reverse
Sequence: Get nucleotide sequence FastaFormat
GC content %:  
 52.05
External database links:  
ASAP:
 ABE-0004309
CGSC:
 31965
ECHOBASE:
 EB0673
ECOLIHUB:
 osmB
OU-MICROARRAY:
 b1283
STRING:
 511145.b1283
COLOMBOS: osmB


Product      
Name: osmotically-inducible lipoprotein OsmB
Synonym(s): OsmB
Sequence: Get amino acid sequence Fasta Format
Cellular location: inner membrane,outer membrane,periplasmic space
Molecular weight: 6.948
Isoelectric point: 10.789
Motif(s):
 
Type Positions Sequence
34 -> 71 TAIGAGAGALGGAVLTDGSTLGTLGGAAVGGVIGHQVG
24 -> 72 CSNWSKRDRNTAIGAGAGALGGAVLTDGSTLGTLGGAAVGGVIGHQVGK
1 -> 23 MFVTSKKMTAAVLAITLAMSLSA

 
Classification:
Multifun Terms (GenProtEC)  
  5 - cell processes --> 5.5 - adaptations --> 5.5.1 - osmotic pressure
Gene Ontology Terms (GO)  
cellular_component GO:0019867 - outer membrane
GO:0016020 - membrane
GO:0030288 - outer membrane-bounded periplasmic space
GO:0005886 - plasma membrane
GO:0036405 - anchored component of cell outer membrane
biological_process GO:0006970 - response to osmotic stress
Note(s): Note(s): ...[more].
Reference(s): [1] Grabowicz M., et al., 2017
[2] Rao S., et al., 2020
External database links:  
ECOCYC:
 EG10679-MONOMER
ECOLIWIKI:
 b1283
INTERPRO:
 IPR008816
PFAM:
 PF05433
PRIDE:
 P0ADA7
PRODB:
 PRO_000023467
PROSITE:
 PS51257
REFSEQ:
 NP_415799
UNIPROT:
 P0ADA7


Operon      
Name: osmB         
Operon arrangement:
Transcription unit        Promoter
osmB
osmB
osmB


Transcriptional Regulation      
Display Regulation             
Activated by: RcsB


Elements in the selected gene context region unrelated to any object in RegulonDB      

  Type Name Post Left Post Right Strand Notes Evidence (Confirmed, Strong, Weak) References
  promoter TSS_1728 1343368 reverse nd [RS-EPT-CBR] [3]
  promoter TSS_1729 1343371 reverse nd [RS-EPT-CBR] [3]


Evidence    

 [RS-EPT-CBR] RNA-seq using two enrichment strategies for primary transcripts and consistent biological replicates


Reference(s)    

 [1] Grabowicz M., Silhavy TJ., 2017, Redefining the essential trafficking pathway for outer membrane lipoproteins., Proc Natl Acad Sci U S A 114(18):4769-4774

 [2] Rao S., Bates GT., Matthews CR., Newport TD., Vickery ON., Stansfeld PJ., 2020, Characterizing Membrane Association and Periplasmic Transfer of Bacterial Lipoproteins through Molecular Dynamics Simulations., Structure 28(4):475-487.e3

 [3] Salgado H, Peralta-Gil M, Gama-Castro S, Santos-Zavaleta A, Muñiz-Rascado L, García-Sotelo JS, Weiss V, Solano-Lira H, Martínez-Flores I, Medina-Rivera A, Salgado-Osorio G, Alquicira-Hernández S, Alquicira-Hernández K, López-Fuentes A, Porrón-Sotelo L, Huerta AM, Bonavides-Martínez C, Balderas-Martínez YI, Pannier L, Olvera M, Labastida A, Jiménez-Jacinto V, Vega-Alvarado L, Del Moral-Chávez V, Hernández-Alvarez A, Morett E, Collado-Vides J., 2012, RegulonDB v8.0: omics data sets, evolutionary conservation, regulatory phrases, cross-validated gold standards and more., Nucleic Acids Res.

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