RegulonDB RegulonDB 11.1: Gene Form
   

phnL gene in Escherichia coli K-12 genome


Gene local context to scale (view description)

phnM phnK phnL phnN phnO phnJ

Gene      
Name: phnL    Texpresso search in the literature
Synonym(s): ECK4089, EG10721, b4096
Genome position(nucleotides): 4317215 <-- 4317895
Strand: reverse
Sequence: Get nucleotide sequence FastaFormat
GC content %:  
 60.21
External database links:  
ASAP:
 ABE-0013421
CGSC:
 34529
ECHOBASE:
 EB0715
ECOLIHUB:
 phnL
OU-MICROARRAY:
 b4096
STRING:
 511145.b4096
COLOMBOS: phnL


Product      
Name: methylphosphonate degradation complex subunit PhnL
Synonym(s): PhnL
Sequence: Get amino acid sequence Fasta Format
Cellular location: inner membrane,cytosol
Molecular weight: 24.705
Isoelectric point: 9.209
Motif(s):
 
Type Positions Sequence Comment
2 -> 226 INVQNVSKTFILHQQNGVRLPVLNRASLTVNAGECVVLHGHSGSGKSTLLRSLYANYLPDEGQIQIKHGDEWVDLVTAPARKVVEIRKTTVGWVSQFLRVIPRISALEVVMQPLLDTGVPREACAAKAARLLTRLNVPERLWHLAPSTFSGGEQQRVNIARGFIVDYPILLLDEPTASLDAKNSAAVVELIREAKTRGAAIVGIFHDEAVRNDVADRLHPMGASS UniProt: ABC transporter.
24 -> 178 LNRASLTVNAGECVVLHGHSGSGKSTLLRSLYANYLPDEGQIQIKHGDEWVDLVTAPARKVVEIRKTTVGWVSQFLRVIPRISALEVVMQPLLDTGVPREACAAKAARLLTRLNVPERLWHLAPSTFSGGEQQRVNIARGFIVDYPILLLDEPTA
41 -> 48 GHSGSGKS UniProt: ATP.

 
Classification:
Multifun Terms (GenProtEC)  
  1 - metabolism --> 1.8 - metabolism of other compounds --> 1.8.1 - phosphorous metabolism
Gene Ontology Terms (GO)  
cellular_component GO:1904176 - carbon phosphorus lyase complex
GO:0005829 - cytosol
GO:0005886 - plasma membrane
GO:0061694 - alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase complex
molecular_function GO:0016740 - transferase activity
GO:0000166 - nucleotide binding
GO:0005524 - ATP binding
GO:0061693 - alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
biological_process GO:0015716 - organic phosphonate transport
GO:0019634 - organic phosphonate metabolic process
GO:0019700 - organic phosphonate catabolic process
Note(s): Note(s): ...[more].
Evidence: [EXP-IMP] Inferred from mutant phenotype
Reference(s): [1] Metcalf WW., et al., 1993
External database links:  
ALPHAFOLD:
 P16679
ECOCYC:
 PHNL-MONOMER
ECOLIWIKI:
 b4096
INTERPRO:
 IPR003439
INTERPRO:
 IPR012701
INTERPRO:
 IPR017871
INTERPRO:
 IPR003593
INTERPRO:
 IPR027417
MODBASE:
 P16679
PFAM:
 PF00005
PRIDE:
 P16679
PRODB:
 PRO_000023537
PROSITE:
 PS50893
PROSITE:
 PS00211
REFSEQ:
 NP_418520
SMART:
 SM00382
SMR:
 P16679
UNIPROT:
 P16679


Operon      
Name: phnCDEFGHIJKLMNOP         
Operon arrangement:
Transcription unit        Promoter
phnCDEEFGHIJKLMNOP
phnLMNOP


Transcriptional Regulation      
Display Regulation             
Activated by: PhoB


Elements in the selected gene context region unrelated to any object in RegulonDB      

  Type Name Post Left Post Right Strand Notes Evidence (Confirmed, Strong, Weak) References


Reference(s)    

 [1] Metcalf WW., Wanner BL., 1993, Mutational analysis of an Escherichia coli fourteen-gene operon for phosphonate degradation, using TnphoA' elements., J Bacteriol 175(11):3430-42

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