RegulonDB RegulonDB 10.10: Gene Form
   

pntB gene in Escherichia coli K-12 genome


Gene local context to scale (view description)

pntA pntB tqsA TSS_1889 TSS_1889 TSS_1888 TSS_1888 pntBp6 pntBp6 TSS_1887 TSS_1887 TSS_1886 TSS_1886 TSS_1885 TSS_1885 TSS_1884 (cluster) TSS_1884 (cluster) TSS_1883 TSS_1883 TSS_1882 TSS_1882

Gene      
Name: pntB    Texpresso search in the literature
Synonym(s): ECK1597, EG10745, b1602
Genome position(nucleotides): 1674972 <-- 1676360 Genome Browser
Strand: reverse
Sequence: Get nucleotide sequence FastaFormat
GC content %:  
 52.63
External database links:  
ASAP:
 ABE-0005352
CGSC:
 18040
ECHOBASE:
 EB0738
ECOLIHUB:
 pntB
OU-MICROARRAY:
 b1602
STRING:
 511145.b1602
COLOMBOS: pntB


Shine dalgarno      
Sequence: cgcaaaaattAAGGGGtaacaTAT


Product      
Name: pyridine nucleotide transhydrogenase subunit β
Synonym(s): PntB
Sequence: Get amino acid sequence Fasta Format
Cellular location: inner membrane
Molecular weight: 48.723
Isoelectric point: 6.084
Motif(s):
 
Type Positions Sequence
46 -> 66 IATIFGPDTGNVGWILLAMVI
240 -> 260 LLIVTGALVGSSGAILSYIMC
4 -> 24 GLVTAAYIVAAILFIFSLAGL
165 -> 185 LAALVVSFLLLIVFVRTDSVG
216 -> 236 VVVSMLNSYSGWAAAAAGFML

 
Classification:
Multifun Terms (GenProtEC)  
  1 - metabolism --> 1.7 - central intermediary metabolism --> 1.7.1 - unassigned reversible reactions
  4 - transport --> 4.9.A - Transporters of Unknown Classification
  6 - cell structure --> 6.1 - membrane
Gene Ontology Terms (GO)  
cellular_component GO:0016020 - membrane
GO:0005886 - plasma membrane
GO:0005887 - integral component of plasma membrane
GO:0016021 - integral component of membrane
molecular_function GO:0005515 - protein binding
GO:0008746 - NAD(P)+ transhydrogenase activity
GO:0008750 - NAD(P)+ transhydrogenase (AB-specific) activity
GO:0050661 - NADP binding
biological_process GO:0006740 - NADPH regeneration
Note(s): Note(s): ...[more].
External database links:  
DIP:
 DIP-367N
ECOCYC:
 PNTB-MONOMER
ECOLIWIKI:
 b1602
INTERPRO:
 IPR034300
INTERPRO:
 IPR029035
INTERPRO:
 IPR012136
MODBASE:
 P0AB67
PDB:
 2BRU
PFAM:
 PF02233
PRIDE:
 P0AB67
PRODB:
 PRO_000023563
REFSEQ:
 NP_416119
SMR:
 P0AB67
SWISSMODEL:
 P0AB67
UNIPROT:
 P0AB67


Operon      
Name: pntAB         
Operon arrangement:
Transcription unit        Promoter
pntAB


Elements in the selected gene context region unrelated to any object in RegulonDB      

  Type Name Post Left Post Right Strand Notes Evidence (Confirmed, Strong, Weak) References
  promoter TSS_1882 1674496 forward nd [RS-EPT-CBR] [1]
  promoter TSS_1883 1675550 reverse nd [RS-EPT-CBR] [1]
  promoter TSS_1884 (cluster) 1676197 reverse nd [RS-EPT-CBR] [1]
  promoter TSS_1885 1676203 reverse nd [RS-EPT-CBR] [1]
  promoter TSS_1886 1676256 reverse nd [RS-EPT-CBR] [1]
  promoter TSS_1887 1676312 reverse nd [RS-EPT-CBR] [1]
  promoter pntBp6 1676548 reverse nd [ICWHO] [2]
  promoter TSS_1888 1676849 reverse nd [RS-EPT-CBR] [1]
  promoter TSS_1889 1677293 reverse nd [RS-EPT-CBR] [1]


Evidence    

 [RS-EPT-CBR] RNA-seq using two enrichment strategies for primary transcripts and consistent biological replicates

 [ICWHO] Inferred computationally without human oversight


Reference(s)    

 [1] Salgado H, Peralta-Gil M, Gama-Castro S, Santos-Zavaleta A, Muñiz-Rascado L, García-Sotelo JS, Weiss V, Solano-Lira H, Martínez-Flores I, Medina-Rivera A, Salgado-Osorio G, Alquicira-Hernández S, Alquicira-Hernández K, López-Fuentes A, Porrón-Sotelo L, Huerta AM, Bonavides-Martínez C, Balderas-Martínez YI, Pannier L, Olvera M, Labastida A, Jiménez-Jacinto V, Vega-Alvarado L, Del Moral-Chávez V, Hernández-Alvarez A, Morett E, Collado-Vides J., 2012, RegulonDB v8.0: omics data sets, evolutionary conservation, regulatory phrases, cross-validated gold standards and more., Nucleic Acids Res.

 [2] Huerta AM., Collado-Vides J., 2003, Sigma70 promoters in Escherichia coli: specific transcription in dense regions of overlapping promoter-like signals., J Mol Biol 333(2):261-78

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