RegulonDB RegulonDB 10.10: Gene Form
   

priC gene in Escherichia coli K-12 genome


Gene local context to scale (view description)

priC ybaN ybaM ybaNp9 ybaNp9 ybaNp6 ybaNp6 ybaNp8 ybaNp8 ybaNp1 ybaNp1 ybaMp3 ybaMp3

Gene      
Name: priC    Texpresso search in the literature
Synonym(s): ECK0461, EG10765, b0467
Genome position(nucleotides): 490285 <-- 490812 Genome Browser
Strand: reverse
Sequence: Get nucleotide sequence FastaFormat
GC content %:  
 58.9
External database links:  
ASAP:
 ABE-0001619
CGSC:
 29161
ECHOBASE:
 EB0758
ECOLIHUB:
 priC
OU-MICROARRAY:
 b0467
STRING:
 511145.b0467
COLOMBOS: priC


Product      
Name: primosomal replication protein N''
Synonym(s): PriC
Sequence: Get amino acid sequence Fasta Format
Cellular location: cytosol
Molecular weight: 20.375
Isoelectric point: 10.613
Motif(s):
 
Type Positions Sequence
2 -> 175 KTALLLEKLEGQLATLRQRCAPVSQFATLSARFDRHLFQTRATTLQACLDEAGDNLAALRHAVEQQQLPQVAWLAEHLAAQLEAIAREASAWSLREWDSAPPKIARWQRKRIQHQDFERRLREMVAERRARLARVTDLVEQQTLHREVEAYEARLARCRHALEKIENRLARLTR
9 -> 173 KLEGQLATLRQRCAPVSQFATLSARFDRHLFQTRATTLQACLDEAGDNLAALRHAVEQQQLPQVAWLAEHLAAQLEAIAREASAWSLREWDSAPPKIARWQRKRIQHQDFERRLREMVAERRARLARVTDLVEQQTLHREVEAYEARLARCRHALEKIENRLARL

 
Classification:
Multifun Terms (GenProtEC)  
  2 - information transfer --> 2.1 - DNA related --> 2.1.1 - DNA replication
Gene Ontology Terms (GO)  
cellular_component GO:0005829 - cytosol
GO:1990077 - primosome complex
molecular_function GO:0003677 - DNA binding
GO:0005515 - protein binding
biological_process GO:0006261 - DNA-dependent DNA replication
GO:0006270 - DNA replication initiation
GO:0006269 - DNA replication, synthesis of RNA primer
Note(s): Note(s): ...[more].
Evidence: [APPH] Assay of protein purified to homogeneity
Reference(s): [1] Ng JY., et al., 1996
[2] Zavitz KH., et al., 1991
External database links:  
DIP:
 DIP-10564N
ECOCYC:
 EG10765-MONOMER
ECOLIWIKI:
 b0467
INTERPRO:
 IPR010890
INTERPRO:
 IPR038338
PDB:
 2RT6
PFAM:
 PF07445
PRIDE:
 P23862
PRODB:
 PRO_000023593
REFSEQ:
 NP_415000
SMR:
 P23862
UNIPROT:
 P23862


Operon      
Name: priC-ybaM         
Operon arrangement:
Transcription unit        Promoter
priC-ybaM


Elements in the selected gene context region unrelated to any object in RegulonDB      

  Type Name Post Left Post Right Strand Notes Evidence (Confirmed, Strong, Weak) References
  promoter ybaMp3 490324 reverse nd [ICWHO] [3]
  promoter ybaNp1 490718 forward nd [ICWHO] [3]
  promoter ybaNp8 490857 forward nd [ICWHO] [3]
  promoter ybaNp6 490873 forward nd [ICWHO] [3]
  promoter ybaNp9 490879 forward nd [ICWHO] [3]


Evidence    

 [ICWHO] Inferred computationally without human oversight


Reference(s)    

 [1] Ng JY., Marians KJ., 1996, The ordered assembly of the phiX174-type primosome. I. Isolation and identification of intermediate protein-DNA complexes., J Biol Chem 271(26):15642-8

 [2] Zavitz KH., DiGate RJ., Marians KJ., 1991, The priB and priC replication proteins of Escherichia coli. Genes, DNA sequence, overexpression, and purification., J Biol Chem 266(21):13988-95

 [3] Huerta AM., Collado-Vides J., 2003, Sigma70 promoters in Escherichia coli: specific transcription in dense regions of overlapping promoter-like signals., J Mol Biol 333(2):261-78

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