RegulonDB RegulonDB 11.1: Gene Form
   

speE gene in Escherichia coli K-12 genome


Gene local context to scale (view description)

speE speD yacC speEp speEp speDp speDp

Gene      
Name: speE    Texpresso search in the literature
Synonym(s): ECK0120, EG10963, b0121
Genome position(nucleotides): 135598 <-- 136464
Strand: reverse
Sequence: Get nucleotide sequence FastaFormat
GC content %:  
 50.75
External database links:  
ASAP:
 ABE-0000418
CGSC:
 17590
ECHOBASE:
 EB0956
ECOLIHUB:
 speE
NCBI-GENE:
 947726
OU-MICROARRAY:
 b0121
STRING:
 511145.b0121
COLOMBOS: speE


Product      
Name: spermidine synthase
Synonym(s): SpeE
Sequence: Get amino acid sequence Fasta Format
Cellular location: cytosol
Molecular weight: 32.321
Isoelectric point: 5.448
Motif(s):
 
Type Positions Sequence Comment
2 -> 288 AEKKQWHETLHDQFGQYFAVDNVLYHEKTDHQDLIIFENAAFGRVMALDGVVQTTERDEFIYHEMMTHVPLLAHGHAKHVLIIGGGDGAMLREVTRHKNVESITMVEIDAGVVSFCRQYLPNHNAGSYDDPRFKLVIDDGVNFVNQTSQTFDVIISDCTDPIGPGESLFTSAFYEGCKRCLNPGGIFVAQNGVCFLQQEEAIDSHRKLSHYFSDVGFYQAAIPTYYGGIMTFAWATDNDALRHLSTEIIQARFLASGLKCRYYNPAIHTAAFALPQYLQDALASQPS UniProt: Polyamine aminopropyltransferase.
6 -> 57 QWHETLHDQFGQYFAVDNVLYHEKTDHQDLIIFENAAFGRVMALDGVVQTTE
9 -> 238 ETLHDQFGQYFAVDNVLYHEKTDHQDLIIFENAAFGRVMALDGVVQTTERDEFIYHEMMTHVPLLAHGHAKHVLIIGGGDGAMLREVTRHKNVESITMVEIDAGVVSFCRQYLPNHNAGSYDDPRFKLVIDDGVNFVNQTSQTFDVIISDCTDPIGPGESLFTSAFYEGCKRCLNPGGIFVAQNGVCFLQQEEAIDSHRKLSHYFSDVGFYQAAIPTYYGGIMTFAWATD UniProt: PABS.
60 -> 239 EFIYHEMMTHVPLLAHGHAKHVLIIGGGDGAMLREVTRHKNVESITMVEIDAGVVSFCRQYLPNHNAGSYDDPRFKLVIDDGVNFVNQTSQTFDVIISDCTDPIGPGESLFTSAFYEGCKRCLNPGGIFVAQNGVCFLQQEEAIDSHRKLSHYFSDVGFYQAAIPTYYGGIMTFAWATDN
140 -> 141 DG UniProt: S-methyl-5'-thioadenosine binding; Sequence Annotation Type: region of interest.

 
Classification:
Multifun Terms (GenProtEC)  
  1 - metabolism --> 1.7 - central intermediary metabolism --> 1.7.14 - polyamine biosynthesis
Gene Ontology Terms (GO)  
cellular_component GO:0005737 - cytoplasm
GO:0005829 - cytosol
molecular_function GO:0003824 - catalytic activity
GO:0016740 - transferase activity
GO:0004766 - spermidine synthase activity
GO:0042803 - protein homodimerization activity
GO:0010487 - thermospermine synthase activity
GO:0016768 - spermine synthase activity
GO:0043918 - cadaverine aminopropyltransferase activity
biological_process GO:0006596 - polyamine biosynthetic process
GO:0008295 - spermidine biosynthetic process
External database links:  
ALPHAFOLD:
 P09158
ECOCYC:
 SPERMIDINESYN-MONOMER
ECOLIWIKI:
 b0121
INTERPRO:
 IPR030373
INTERPRO:
 IPR001045
INTERPRO:
 IPR035246
INTERPRO:
 IPR037163
INTERPRO:
 IPR030374
INTERPRO:
 IPR029063
MODBASE:
 P09158
PDB:
 3O4F
PFAM:
 PF17284
PFAM:
 PF01564
PRIDE:
 P09158
PROSITE:
 PS51006
PROSITE:
 PS01330
REFSEQ:
 NP_414663
SMR:
 P09158
UNIPROT:
 P09158


Operon      
Name: yacC-speED         
Operon arrangement:
Transcription unit        Promoter
speD
speE
yacC-speED


Elements in the selected gene context region unrelated to any object in RegulonDB      

  Type Name Post Left Post Right Strand Notes Evidence (Confirmed, Strong, Weak) References



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