RegulonDB RegulonDB 11.0: Gene Form
   

gutQ gene in Escherichia coli K-12 genome


Gene local context to scale (view description)

norR norV gutQ srlR gutM norW IHF IHF NarL NarP NarL NarP NorR NorR NorR FNR NsrR terminator norVp norVp norRp norRp TSS_3019 TSS_3019 TSS_3018 (cluster) TSS_3018 (cluster) TSS_3017 (cluster) TSS_3017 (cluster) srlRp srlRp

Gene      
Name: gutQ    Texpresso search in the literature
Synonym(s): ECK2703, EG10973, b2708, srlQ
Genome position(nucleotides): 2829813 --> 2830778
Strand: forward
Sequence: Get nucleotide sequence FastaFormat
GC content %:  
57.35
External database links:  
ASAP:
ABE-0008902
CGSC:
33206
ECHOBASE:
EB0966
ECOLIHUB:
gutQ
OU-MICROARRAY:
b2708
STRING:
511145.b2708
COLOMBOS: gutQ


Product      
Name: D-arabinose 5-phosphate isomerase GutQ
Synonym(s): GutQ, SrlQ
Sequence: Get amino acid sequence Fasta Format
Cellular location: cytosol
Molecular weight: 34.031
Isoelectric point: 6.313
Motif(s):
 
Type Positions Sequence Comment
2 -> 321 SEALLNAGRQTLMLELQEASRLPERLGDDFVRAANIILHCEGKVVVSGIGKSGHIGKKIAATLASTGTPAFFVHPAEALHGDLGMIESRDVMLFISYSGGAKELDLIIPRLEDKSIALLAMTGKPTSPLGLAAKAVLDISVEREACPMHLAPTSSTVNTLMMGDALAMAVMQARGFNEEDFARSHPAGALGARLLNKVHHLMRRDDAIPQVALTASVMDAMLELSRTGLGLVAVCDAQQQVQGVFTDGDLRRWLVGGGALTTPVNEAMTVGGTTLQSQSRAIDAKEILMKRKITAAPVVDENGKLTGAINLQDFYQAGII UniProt: Arabinose 5-phosphate isomerase GutQ.
34 -> 177 AANIILHCEGKVVVSGIGKSGHIGKKIAATLASTGTPAFFVHPAEALHGDLGMIESRDVMLFISYSGGAKELDLIIPRLEDKSIALLAMTGKPTSPLGLAAKAVLDISVEREACPMHLAPTSSTVNTLMMGDALAMAVMQARGF UniProt: SIS.
38 -> 170 ILHCEGKVVVSGIGKSGHIGKKIAATLASTGTPAFFVHPAEALHGDLGMIESRDVMLFISYSGGAKELDLIIPRLEDKSIALLAMTGKPTSPLGLAAKAVLDISVEREACPMHLAPTSSTVNTLMMGDALAMA
49 -> 54 GIGKSG UniProt: ATP.
68 -> 69 GT UniProt: Substrate binding; Sequence Annotation Type: region of interest.

 

Classification:
Multifun Terms (GenProtEC)  
  1 - metabolism --> 1.6 - biosynthesis of macromolecules (cellular constituents) --> 1.6.3 - lipopolysaccharide --> 1.6.3.2 - core region
Gene Ontology Terms (GO)  
cellular_component GO:0005829 - cytosol
molecular_function GO:0016853 - isomerase activity
GO:0046872 - metal ion binding
GO:0019146 - arabinose-5-phosphate isomerase activity
GO:0000166 - nucleotide binding
GO:0005524 - ATP binding
GO:0042802 - identical protein binding
GO:0097367 - carbohydrate derivative binding
biological_process GO:0005975 - carbohydrate metabolic process
GO:0009103 - lipopolysaccharide biosynthetic process
GO:0019294 - keto-3-deoxy-D-manno-octulosonic acid biosynthetic process
GO:0044010 - single-species biofilm formation
GO:0051289 - protein homotetramerization
GO:1901135 - carbohydrate derivative metabolic process
Note(s): Note(s): ...[more].
External database links:  
ALPHAFOLD:
P17115
ECOCYC:
EG10973-MONOMER
ECOLIWIKI:
b2708
INTERPRO:
IPR004800
INTERPRO:
IPR035474
INTERPRO:
IPR001347
INTERPRO:
IPR000644
MODBASE:
P17115
PFAM:
PF01380
PFAM:
PF00571
PRIDE:
P17115
PROSITE:
PS51371
PROSITE:
PS51464
REFSEQ:
NP_417188
SMR:
P17115
UNIPROT:
P17115


Operon      
Name: srlAEBD-gutM-srlR-gutQ         
Operon arrangement:
Transcription unit        Promoter
srlAEBD-gutM-srlR-gutQ
srlR


Transcriptional Regulation      
Display Regulation             
Activated by: CRP, H-NS, GutM
Repressed by: SrlR


Elements in the selected gene context region unrelated to any object in RegulonDB      

  Type Name Post Left Post Right Strand Notes Evidence (Confirmed, Strong, Weak) References
  promoter TSS_3017 (cluster) 2828961 forward nd [RS-EPT-CBR] [1]
  promoter TSS_3018 (cluster) 2829709 forward nd [RS-EPT-CBR] [1]
  promoter TSS_3019 2829746 forward nd [RS-EPT-CBR] [1]


Evidence    

 [RS-EPT-CBR] RNA-seq using two enrichment strategies for primary transcripts and consistent biological replicates



Reference(s)    

 [1] Salgado H, Peralta-Gil M, Gama-Castro S, Santos-Zavaleta A, Muñiz-Rascado L, García-Sotelo JS, Weiss V, Solano-Lira H, Martínez-Flores I, Medina-Rivera A, Salgado-Osorio G, Alquicira-Hernández S, Alquicira-Hernández K, López-Fuentes A, Porrón-Sotelo L, Huerta AM, Bonavides-Martínez C, Balderas-Martínez YI, Pannier L, Olvera M, Labastida A, Jiménez-Jacinto V, Vega-Alvarado L, Del Moral-Chávez V, Hernández-Alvarez A, Morett E, Collado-Vides J., 2012, RegulonDB v8.0: omics data sets, evolutionary conservation, regulatory phrases, cross-validated gold standards and more., Nucleic Acids Res.


RegulonDB