RegulonDB RegulonDB 10.10: Gene Form
   

tdcB gene in Escherichia coli K-12 genome


Gene local context to scale (view description)

tdcC tdcB tdcA

Gene      
Name: tdcB    Texpresso search in the literature
Synonym(s): ECK3106, EG10990, b3117, tdc
Genome position(nucleotides): 3265039 <-- 3266028 Genome Browser
Strand: reverse
Sequence: Get nucleotide sequence FastaFormat
GC content %:  
 46.36
External database links:  
ASAP:
 ABE-0010249
CGSC:
 17587
ECHOBASE:
 EB0983
ECOLIHUB:
 tdcB
OU-MICROARRAY:
 b3117
STRING:
 511145.b3117
COLOMBOS: tdcB


Product      
Name: catabolic threonine dehydratase
Synonym(s): Tdc, TdcB
Sequence: Get amino acid sequence Fasta Format
Cellular location: cytosol
Molecular weight: 35.232
Isoelectric point: 5.982
Motif(s):
 
Type Positions Sequence
119 -> 120 DY
25 -> 312 IYKTGMPRSNYFSERCKGEIFLKFENMQRTGSFKIRGAFNKLSSLTDAEKRKGVVACSAGNHAQGVSLSCAMLGIDGKVVMPKGAPKSKVAATCDYSAEVVLHGDNFNDTIAKVSEIVEMEGRIFIPPYDDPKVIAGQGTIGLEIMEDLYDVDNVIVPIGGGGLIAGIAVAIKSINPTIRVIGVQSENVHGMAASFHSGEITTHRTTGTLADGCDVSRPGNLTYEIVRELVDDIVLVSEDEIRNSMIALIQRNKVVTEGAGALACAALLSGKLDQYIQNRKTVSIISG
53 -> 54 RT

 
Classification:
Multifun Terms (GenProtEC)  
  1 - metabolism --> 1.1 - carbon utilization --> 1.1.3 - amino acids
  1 - metabolism --> 1.7 - central intermediary metabolism --> 1.7.30 - threonine catabolism
Gene Ontology Terms (GO)  
cellular_component GO:0005829 - cytosol
GO:0032991 - protein-containing complex
molecular_function GO:0003824 - catalytic activity
GO:0016829 - lyase activity
GO:0004793 - threonine aldolase activity
GO:0000166 - nucleotide binding
GO:0016597 - amino acid binding
GO:0030170 - pyridoxal phosphate binding
GO:0003941 - L-serine ammonia-lyase activity
GO:0004794 - L-threonine ammonia-lyase activity
GO:0042802 - identical protein binding
biological_process GO:0008152 - metabolic process
GO:0006520 - cellular amino acid metabolic process
GO:0006565 - L-serine catabolic process
GO:0006567 - threonine catabolic process
GO:0070689 - L-threonine catabolic process to propionate
GO:0051289 - protein homotetramerization
External database links:  
DIP:
 DIP-48063N
ECOCYC:
 THREDEHYDCAT-MONOMER
ECOLIWIKI:
 b3117
INTERPRO:
 IPR036052
INTERPRO:
 IPR005789
INTERPRO:
 IPR001926
INTERPRO:
 IPR000634
MODBASE:
 P0AGF6
PFAM:
 PF00291
PRIDE:
 P0AGF6
PRODB:
 PRO_000024038
PROSITE:
 PS00165
REFSEQ:
 NP_417587
SMR:
 P0AGF6
UNIPROT:
 P0AGF6


Operon      
Name: tdcABCDEFG         
Operon arrangement:
Transcription unit        Promoter
tdcABCDEFG
tdcBCDEFG


Transcriptional Regulation      
Display Regulation             
Activated by: TdcA, CRP, TdcR, FNR, IHF


Elements in the selected gene context region unrelated to any object in RegulonDB      

  Type Name Post Left Post Right Strand Notes Evidence (Confirmed, Strong, Weak) References



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