RegulonDB RegulonDB 11.1: Gene Form
   

ugpA gene in Escherichia coli K-12 genome


Gene local context to scale (view description)

ugpB ugpC ugpA ugpE ugpQ terminator ugpQp1 ugpQp1

Gene      
Name: ugpA    Texpresso search in the literature
Synonym(s): ECK3436, EG11046, b3452, psiB, psiC, ugp
Genome position(nucleotides): 3590024 <-- 3590911
Strand: reverse
Sequence: Get nucleotide sequence FastaFormat
GC content %:  
55.86
External database links:  
ASAP:
ABE-0011272
CGSC:
40
ECHOBASE:
EB1039
ECOLIHUB:
ugpA
OU-MICROARRAY:
b3452
STRING:
511145.b3452
COLOMBOS: ugpA


Product      
Name: sn-glycerol 3-phosphate ABC transporter membrane subunit UgpA
Synonym(s): PsiB, PsiC, Ugp, UgpA
Sequence: Get amino acid sequence Fasta Format
Cellular location: inner membrane
Molecular weight: 33.264
Isoelectric point: 9.033
Motif(s):
 
Type Positions Sequence Comment
12 -> 32 WLPYLLVAPQLIITVIFFIWP UniProt: Helical.
76 -> 284 IKFSTFVTVSGLLVSLFFAALVEYIVRGSRFYQTLMLLPYAVAPAVAAVLWIFLFNPGRGLITHFLAEFGYDWNHAQNSGQAMFLVVFASVWKQISYNFLFFYAALQSIPRSLIEAAAIDGAGPIRRFFKIALPLIAPVSFFLLVVNLVYAFFDTFPVIDAATSGGPVQATTTLIYKIYREGFTGLDLASSAAQSVVLMFLVIVLTVVQ UniProt: ABC transmembrane type-1.
81 -> 101 FVTVSGLLVSLFFAALVEYIV UniProt: Helical.
88 -> 293 LVSLFFAALVEYIVRGSRFYQTLMLLPYAVAPAVAAVLWIFLFNPGRGLITHFLAEFGYDWNHAQNSGQAMFLVVFASVWKQISYNFLFFYAALQSIPRSLIEAAAIDGAGPIRRFFKIALPLIAPVSFFLLVVNLVYAFFDTFPVIDAATSGGPVQATTTLIYKIYREGFTGLDLASSAAQSVVLMFLVIVLTVVQFRYVESKVR
110 -> 130 LMLLPYAVAPAVAAVLWIFLF UniProt: Helical.

 

Classification:
Multifun Terms (GenProtEC)  
  1 - metabolism --> 1.8 - metabolism of other compounds --> 1.8.1 - phosphorous metabolism
  6 - cell structure --> 6.1 - membrane
  4 - transport --> 4.3 - Primary Active Transporters --> 4.3.A - Pyrophosphate Bond (ATP; GTP; P2) Hydrolysis-driven Active Transporters --> 4.3.A.1 - The ATP-binding Cassette (ABC) Superfamily + ABC-type Uptake Permeases --> 4.3.A.1.m - ABC superfamily, membrane component
Gene Ontology Terms (GO)  
cellular_component GO:1902517 - glycerol-3-phosphate-transporting ATPase complex
GO:0016020 - membrane
GO:0005886 - plasma membrane
GO:0005887 - integral component of plasma membrane
GO:0016021 - integral component of membrane
GO:0055052 - ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing
molecular_function GO:0015169 - glycerol-3-phosphate transmembrane transporter activity
GO:0001406 - glycerophosphodiester transmembrane transporter activity
biological_process GO:0015794 - glycerol-3-phosphate transmembrane transport
GO:0055085 - transmembrane transport
GO:0001407 - glycerophosphodiester transmembrane transport
Note(s): Note(s): ...[more].
External database links:  
ALPHAFOLD:
P10905
DIP:
DIP-11077N
ECOCYC:
UGPA-MONOMER
ECOLIWIKI:
b3452
INTERPRO:
IPR035906
INTERPRO:
IPR000515
PFAM:
PF00528
PRIDE:
P10905
PRODB:
PRO_000024164
PROSITE:
PS50928
REFSEQ:
NP_417909
UNIPROT:
P10905


Operon      
Name: ugpBAECQ         
Operon arrangement:
Transcription unit        Promoter
ugpBAECQ
ugpBAECQ


Transcriptional Regulation      
Display Regulation             
Activated by: CRP, PhoB
Repressed by: PhoB


RNA cis-regulatory element    
Attenuation: Translational


Elements in the selected gene context region unrelated to any object in RegulonDB      

  Type Name Post Left Post Right Strand Notes Evidence (Confirmed, Strong, Weak) References
  promoter ugpQp1 3588300 reverse nd [COMP-AINF] [1]


Evidence    

 [COMP-AINF] Inferred computationally without human oversight



Reference(s)    

 [1] Huerta AM., Collado-Vides J., 2003, Sigma70 promoters in Escherichia coli: specific transcription in dense regions of overlapping promoter-like signals., J Mol Biol 333(2):261-78


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