RegulonDB RegulonDB 10.8: Gene Form
   

ugpQ gene in Escherichia coli K-12 genome


Gene local context to scale (view description)

ggt ugpC ugpE ugpQ yhhA ugpA terminator anti-terminator anti-anti-terminator terminator ugpQp1 ugpQp1 TSS_4057 TSS_4057 yhhAp4 yhhAp4 yhhAp6 yhhAp6

Gene      
Name: ugpQ    Texpresso search in the literature
Synonym(s): ECK3433, EG11050, b3449
Genome position(nucleotides): 3587370 <-- 3588113 Genome Browser
Strand: reverse
Sequence: Get nucleotide sequence FastaFormat
GC content %:  
56.45
External database links:  
ASAP:
ABE-0011264
CGSC:
33697
ECHOBASE:
EB1043
OU-MICROARRAY:
b3449
PortEco:
ugpQ
STRING:
511145.b3449
COLOMBOS: ugpQ


Product      
Name: glycerophosphodiester phosphodiesterase UgpQ
Synonym(s): UgpQ, glycerophosphodiester phosphodiesterase, cytosolic
Sequence: Get amino acid sequence Fasta Format
Cellular location: cytosol
Molecular weight: 27.41
Isoelectric point: 6.517
Motif(s):
 
Type Positions Sequence
7 -> 244 PRIVAHRGGGKLAPENTLASIDVGAKYGHKMIEFDAKLSKDGEIFLLHDDNLERTSNGWGVAGELNWQDLLRVDAGSWYSKMFKGEPLPLLSQVAERCREHGMMANIEIKPTTGTGPLTGKMVALAARELWAGMTPPLLSSFEIDALEAAQQAAPELPRGLLLDEWRDDWRELTARLGCVSIHLNHKLLNKARVMQLKDAGLRILVYTVNKPQRAAELLRWGVDCICTDAIDVIGPNF
12 -> 238 HRGGGKLAPENTLASIDVGAKYGHKMIEFDAKLSKDGEIFLLHDDNLERTSNGWGVAGELNWQDLLRVDAGSWYSKMFKGEPLPLLSQVAERCREHGMMANIEIKPTTGTGPLTGKMVALAARELWAGMTPPLLSSFEIDALEAAQQAAPELPRGLLLDEWRDDWRELTARLGCVSIHLNHKLLNKARVMQLKDAGLRILVYTVNKPQRAAELLRWGVDCICTDAID

 

Classification:
Multifun Terms (GenProtEC)  
  1 - metabolism --> 1.7 - central intermediary metabolism --> 1.7.6 - misc. glycerol metabolism
Gene Ontology Terms (GO)  
cellular_component GO:0005737 - cytoplasm
GO:0005829 - cytosol
molecular_function GO:0016787 - hydrolase activity
GO:0046872 - metal ion binding
GO:0008081 - phosphoric diester hydrolase activity
GO:0008889 - glycerophosphodiester phosphodiesterase activity
GO:0000287 - magnesium ion binding
GO:0047389 - glycerophosphocholine phosphodiesterase activity
GO:0047395 - glycerophosphoinositol glycerophosphodiesterase activity
biological_process GO:0006071 - glycerol metabolic process
GO:0006629 - lipid metabolic process
Note(s): Note(s): ...[more].
Reference(s): [1] Tommassen J., et al., 1991
External database links:  
ECOCYC:
GLYCPDIESTER-CYTO-MONOMER
ECOLIWIKI:
b3449
INTERPRO:
IPR017946
INTERPRO:
IPR030395
MODBASE:
P10908
PANTHER:
PTHR23344
PFAM:
PF03009
PRIDE:
P10908
PROSITE:
PS51704
REFSEQ:
NP_417906
SMR:
P10908
SWISSMODEL:
P10908
UNIPROT:
P10908


Operon      
Name: ugpBAECQ         
Operon arrangement:
Transcription unit        Promoter
ugpBAECQ
ugpBAECQ


Transcriptional Regulation      
Display Regulation             
Activated by: CRP, PhoB
Repressed by: PhoB


Elements in the selected gene context region unrelated to any object in RegulonDB      

  Type Name Post Left Post Right Strand Notes Evidence (Confirmed, Strong, Weak) References
  promoter yhhAp6 3586729 forward Similarity to the consensus
Read more >
[ICWHO] [2]
  promoter yhhAp4 3586919 forward Similarity to the consensus
Read more >
[ICWHO] [2]
  promoter TSS_4057 3586920 forward nd [RS-EPT-CBR] [3]
  promoter ugpQp1 3588300 reverse Similarity to the consensus
Read more >
[ICWHO] [2]


Evidence    

 [ICWHO] Inferred computationally without human oversight

 [RS-EPT-CBR] RNA-seq using two enrichment strategies for primary transcripts and consistent biological replicates



Reference(s)    

 [1] Tommassen J., Eiglmeier K., Cole ST., Overduin P., Larson TJ., Boos W., 1991, Characterization of two genes, glpQ and ugpQ, encoding glycerophosphoryl diester phosphodiesterases of Escherichia coli., Mol Gen Genet 226(1-2):321-7

 [2] Huerta AM., Collado-Vides J., 2003, Sigma70 promoters in Escherichia coli: specific transcription in dense regions of overlapping promoter-like signals., J Mol Biol 333(2):261-78

 [3] Salgado H, Peralta-Gil M, Gama-Castro S, Santos-Zavaleta A, Muñiz-Rascado L, García-Sotelo JS, Weiss V, Solano-Lira H, Martínez-Flores I, Medina-Rivera A, Salgado-Osorio G, Alquicira-Hernández S, Alquicira-Hernández K, López-Fuentes A, Porrón-Sotelo L, Huerta AM, Bonavides-Martínez C, Balderas-Martínez YI, Pannier L, Olvera M, Labastida A, Jiménez-Jacinto V, Vega-Alvarado L, Del Moral-Chávez V, Hernández-Alvarez A, Morett E, Collado-Vides J., 2012, RegulonDB v8.0: omics data sets, evolutionary conservation, regulatory phrases, cross-validated gold standards and more., Nucleic Acids Res.


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