Gene
Name:	cspD
Synonym(s):	ECK0871, EG11111, b0880, cspH, ybjA
Genome position(nucleotides):	922366 <-- 922590
Strand:	reverse
Sequence:	Get nucleotide sequence FastaFormat
GC content %:	48.44
External database links:

ASAP:	ABE-0002991
CGSC:	31688
ECHOBASE:	EB1102
ECOLIHUB:	cspD
OU-MICROARRAY:	b0880
STRING:	511145.b0880
COLOMBOS:	cspD

Type	Name	Post Left	Strand	Notes	Evidence (Confirmed, Strong, Weak)	References
promoter	TSS_1026	921483	forward	nd	[RS-EPT-CBR]	[4]
promoter	TSS_1027	921911	forward	nd	[RS-EPT-CBR]	[4]
promoter	TSS_1028 (cluster)	922360	forward	nd	[RS-EPT-CBR]	[4]
promoter	TSS_1029	922660	forward	nd	[RS-EPT-CBR]	[4]
promoter	clpSp6	922750	forward	nd	[COMP-AINF]	[5]

Evidence
[RS-EPT-CBR] RNA-seq using two enrichment strategies for primary transcripts and consistent biological replicates
[COMP-AINF] Inferred computationally without human oversight

Reference(s)
[1] Giuliodori AM., Fabbretti A., Gualerzi C., 2019, Cold-Responsive Regions of Paradigm Cold-Shock and Non-Cold-Shock mRNAs Responsible for Cold Shock Translational Bias., Int J Mol Sci 20(3)
[2] Higuchi K., Yabuki T., Ito M., Kigawa T., 2020, Cold shock proteins improve E. coli cell-free synthesis in terms of soluble yields of aggregation-prone proteins., Biotechnol Bioeng 117(6):1628-1639
[3] Xia B., Ke H., Inouye M., 2001, Acquirement of cold sensitivity by quadruple deletion of the cspA family and its suppression by PNPase S1 domain in Escherichia coli., Mol Microbiol 40(1):179-88
[4] Salgado H, Peralta-Gil M, Gama-Castro S, Santos-Zavaleta A, Muñiz-Rascado L, García-Sotelo JS, Weiss V, Solano-Lira H, Martínez-Flores I, Medina-Rivera A, Salgado-Osorio G, Alquicira-Hernández S, Alquicira-Hernández K, López-Fuentes A, Porrón-Sotelo L, Huerta AM, Bonavides-Martínez C, Balderas-Martínez YI, Pannier L, Olvera M, Labastida A, Jiménez-Jacinto V, Vega-Alvarado L, Del Moral-Chávez V, Hernández-Alvarez A, Morett E, Collado-Vides J., 2012, RegulonDB v8.0: omics data sets, evolutionary conservation, regulatory phrases, cross-validated gold standards and more., Nucleic Acids Res.
[5] Huerta AM., Collado-Vides J., 2003, Sigma70 promoters in Escherichia coli: specific transcription in dense regions of overlapping promoter-like signals., J Mol Biol 333(2):261-78

Transcriptional Regulation
	Display Regulation
Activated by:	CRP, H-NS
Repressed by:	MqsA