RegulonDB RegulonDB 10.9: Gene Form
   

yfcA gene in Escherichia coli K-12 genome


Gene local context to scale (view description)

aroC mepA yfcA epmC yfcL TSS_2645 TSS_2645 TSS_2644 (cluster) TSS_2644 (cluster) TSS_2643 TSS_2643 TSS_2642 TSS_2642 TSS_2641 (cluster) TSS_2641 (cluster) TSS_2640 (cluster) TSS_2640 (cluster) TSS_2639 (cluster) TSS_2639 (cluster) TSS_2638 TSS_2638 TSS_2637 TSS_2637 yfcLp5 yfcLp5

Gene      
Name: yfcA    Texpresso search in the literature
Synonym(s): ECK2321, EG11144, b2327
Genome position(nucleotides): 2444751 <-- 2445560 Genome Browser
Strand: reverse
Sequence: Get nucleotide sequence FastaFormat
GC content %:  
52.72
External database links:  
ASAP:
ABE-0007689
ECHOBASE:
EB1134
ECOLIHUB:
yfcA
OU-MICROARRAY:
b2327
STRING:
511145.b2327
COLOMBOS: yfcA


Product      
Name: putative transporter YfcA
Synonym(s): YfcA
Sequence: Get amino acid sequence Fasta Format
Cellular location: inner membrane
Molecular weight: 28.643
Isoelectric point: 9.955
Motif(s):
 
Type Positions Sequence
85 -> 105 LNIAMTFVGSMSGALLVQYVQ
8 -> 28 FMVSPLLLGVLFFVAMLAGFI
18 -> 253 LFFVAMLAGFIDSIAGGGGLLTIPALMAAGMSPANALATNKLQACGGSISATIYFIRRKVVSLSDQKLNIAMTFVGSMSGALLVQYVQADVLRQILPILVICIGLYFLLMPKLGEEDRQRRMYGLPFALIAGGCVGFYDGFFGPAAGSFYALAFVTLCGFNLAKATAHAKLLNATSNIGGLLLFILGGKVIWATGFVMLVGQFLGARMGSRLVLSKGQKLIRPMIVIVSAVMSAKL
31 -> 51 IAGGGGLLTIPALMAAGMSPA
112 -> 132 ILPILVICIGLYFLLMPKLGE

 

Classification:
Multifun Terms (GenProtEC)  
Gene Ontology Terms (GO)  
cellular_component GO:0016020 - membrane
GO:0005886 - plasma membrane
GO:0005887 - integral component of plasma membrane
GO:0016021 - integral component of membrane
biological_process GO:0009408 - response to heat
Note(s): Note(s): ...[more].
External database links:  
ECOCYC:
EG11144-MONOMER
ECOLIWIKI:
b2327
INTERPRO:
IPR002781
PFAM:
PF01925
PRIDE:
P0AD30
REFSEQ:
NP_416830
UNIPROT:
P0AD30


Operon      
Name: prmB-aroC-mepA-yfcA-epmC-yfcL         
Operon arrangement:
Transcription unit        Promoter
prmB-aroC-mepA-yfcA-epmC-yfcL


Elements in the selected gene context region unrelated to any object in RegulonDB      

  Type Name Post Left Post Right Strand Notes Evidence (Confirmed, Strong, Weak) References
  promoter yfcLp5 2444251 reverse Similarity to the consensus
Read more >
[ICWHO] [1]
  promoter TSS_2637 2444742 reverse nd [RS-EPT-CBR] [2]
  promoter TSS_2638 2444784 reverse nd [RS-EPT-CBR] [2]
  promoter TSS_2639 (cluster) 2444800 reverse For this promoter, there
Read more >
[RS-EPT-CBR] [2]
  promoter TSS_2640 (cluster) 2444805 reverse For this promoter, there
Read more >
[RS-EPT-CBR] [2]
  promoter TSS_2641 (cluster) 2444859 reverse For this promoter, there
Read more >
[RS-EPT-CBR] [2]
  promoter TSS_2642 2444872 reverse nd [RS-EPT-CBR] [2]
  promoter TSS_2643 2444876 reverse nd [RS-EPT-CBR] [2]
  promoter TSS_2644 (cluster) 2444884 reverse For this promoter, there
Read more >
[RS-EPT-CBR] [2]
  promoter TSS_2645 2445745 reverse nd [RS-EPT-CBR] [2]


Evidence    

 [ICWHO] Inferred computationally without human oversight

 [RS-EPT-CBR] RNA-seq using two enrichment strategies for primary transcripts and consistent biological replicates



Reference(s)    

 [1] Huerta AM., Collado-Vides J., 2003, Sigma70 promoters in Escherichia coli: specific transcription in dense regions of overlapping promoter-like signals., J Mol Biol 333(2):261-78

 [2] Salgado H, Peralta-Gil M, Gama-Castro S, Santos-Zavaleta A, Muñiz-Rascado L, García-Sotelo JS, Weiss V, Solano-Lira H, Martínez-Flores I, Medina-Rivera A, Salgado-Osorio G, Alquicira-Hernández S, Alquicira-Hernández K, López-Fuentes A, Porrón-Sotelo L, Huerta AM, Bonavides-Martínez C, Balderas-Martínez YI, Pannier L, Olvera M, Labastida A, Jiménez-Jacinto V, Vega-Alvarado L, Del Moral-Chávez V, Hernández-Alvarez A, Morett E, Collado-Vides J., 2012, RegulonDB v8.0: omics data sets, evolutionary conservation, regulatory phrases, cross-validated gold standards and more., Nucleic Acids Res.


RegulonDB