RegulonDB RegulonDB 11.1: Gene Form
   

argO gene in Escherichia coli K-12 genome


Gene local context to scale (view description)

mscS yggE argO och5 Lrp Lrp ArgP Lrp ArgP argOp argOp yggEp2 yggEp2 yggEp1 yggEp1

Gene      
Name: argO    Texpresso search in the literature
Synonym(s): ECK2919, EG11159, b2923, yggA
Genome position(nucleotides): 3068173 <-- 3068808
Strand: reverse
Sequence: Get nucleotide sequence FastaFormat
GC content %:  
 50.79
External database links:  
ASAP:
 ABE-0009591
ECHOBASE:
 EB1148
ECOLIHUB:
 argO
OU-MICROARRAY:
 b2923
STRING:
 511145.b2923
COLOMBOS: argO


Product      
Name: L-arginine exporter
Synonym(s): ArgO, YggA
Sequence: Get amino acid sequence Fasta Format
Cellular location: inner membrane
Molecular weight: 23.176
Isoelectric point: 9.809
Motif(s):
 
Type Positions Sequence Comment
1 -> 21 MFSYYFQGLALGAAMILPLGP UniProt: Helical.
14 -> 201 AMILPLGPQNAFVMNQGIRRQYHIMIALLCAISDLVLICAGIFGGSALLMQSPWLLALVTWGGVAFLLWYGFGAFKTAMSSNIELASAEVMKQGRWKIIATMLAVTWLNPHVYLDTFVVLGSLGGQLDVEPKRWFALGTISASFLWFFGLALLAAWLAPRLRTAKAQRIINLVVGCVMWFIALQLARD
20 -> 20 G G → C: loss of function mutation
22 -> 22 Q Q → R: loss of function mutation
37 -> 57 IMIALLCAISDLVLICAGIFG UniProt: Helical.

 
Classification:
Multifun Terms (GenProtEC)  
  4 - transport --> 4.2 - Electrochemical potential driven transporters --> 4.2.A - Porters (Uni-, Sym- and Antiporters)
Gene Ontology Terms (GO)  
cellular_component GO:0016020 - membrane
GO:0005886 - plasma membrane
GO:0005887 - integral component of plasma membrane
GO:0016021 - integral component of membrane
molecular_function GO:0061459 - L-arginine transmembrane transporter activity
GO:0015171 - amino acid transmembrane transporter activity
biological_process GO:0006865 - amino acid transport
GO:1903826 - L-arginine transmembrane transport
Note(s): Note(s): ...[more].
Reference(s): [1] Marbaniang CN., et al., 2012
External database links:  
ALPHAFOLD:
 P11667
ECOCYC:
 YGGA-MONOMER
ECOLIWIKI:
 b2923
INTERPRO:
 IPR004777
INTERPRO:
 IPR001123
INTERPRO:
 IPR023445
PANTHER:
 PTHR30086
PFAM:
 PF01810
PRIDE:
 P11667
PRODB:
 PRO_000022133
REFSEQ:
 NP_417398
UNIPROT:
 P11667


Operon      
Name: argO         
Operon arrangement:
Transcription unit        Promoter
argO


Transcriptional Regulation      
Display Regulation             
Activated by: ArgP, Lrp


Elements in the selected gene context region unrelated to any object in RegulonDB      

  Type Name Post Left Post Right Strand Notes Evidence (Confirmed, Strong, Weak) References


Reference(s)    

 [1] Marbaniang CN., Gowrishankar J., 2012, Transcriptional cross-regulation between Gram-negative and gram-positive bacteria, demonstrated using ArgP-argO of Escherichia coli and LysG-lysE of Corynebacterium glutamicum., J Bacteriol 194(20):5657-66

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