RegulonDB

Gene
Name:	hisL
Synonym(s):	ECK2013, EG11269, b2018
Genome position(nucleotides):	2089996 --> 2090046 Genome Browser
Strand:	forward
Sequence:	Get nucleotide sequence FastaFormat
GC content %:	43.14
External database links:

ASAP:	ABE-0006710
ECHOBASE:	EB1248
ECOLIHUB:	hisL
OU-MICROARRAY:	b2018
STRING:	511145.b2018
COLOMBOS:	hisL

Product

Name:

his operon leader peptide

Synonym(s):

HisL

Sequence:

Get amino acid sequence Fasta Format

Cellular location:

cytosol

Molecular weight:

2.081

Isoelectric point:

9.706

Motif(s):

Type	Positions	Sequence
	1 -> 16	MTRVQFKHHHHHHHPD

Classification:

Multifun Terms (GenProtEC)
Multifun Terms (GenProtEC)		1 - metabolism --> 1.5 - biosynthesis of building blocks --> 1.5.1 - amino acids --> 1.5.1.16 - histidine
Gene Ontology Terms (GO)
	cellular_component	GO:0005829 - cytosol
	biological_process	GO:0000105 - histidine biosynthetic process GO:0008652 - cellular amino acid biosynthetic process

Note(s):

Note(s): ...[more].

External database links:

ECOCYC:

ECOLIWIKI:

INTERPRO:

PFAM:

PRIDE:

REFSEQ:

UNIPROT:

Operon

Name:

hisLGDCBHAFI

Operon arrangement:

Elements in the selected gene context region unrelated to any object in RegulonDB

Type	Name	Post Left	Strand	Notes	Evidence (Confirmed, Strong, Weak)	References
promoter	TSS_2325	2089731	reverse	nd	[RS-EPT-CBR]	[1]
promoter	TSS_2327	2089902	reverse	nd	[RS-EPT-CBR]	[1]
promoter	TSS_2329	2089980	forward	nd	[RS-EPT-CBR]	[1]
promoter	TSS_2330 (cluster)	2089990	forward	For this promoter, there is a cluster of 7 transcription start sites,in the interval 2089990 to 2089996, where the highest frequency is at position 2088018. The most upstream position of this cluster is assigned as TSS position in the promoter. Read more >	[RS-EPT-CBR]	[1]
promoter	TSS_2331 (cluster)	2089999	forward	For this promoter, there is a cluster of 2 transcription start sites,in the interval 2089999 to 2090000, where the highest frequency is at position 2088023. The most upstream position of this cluster is assigned as TSS position in the promoter. Read more >	[RS-EPT-CBR]	[1]
promoter	TSS_2332	2090173	forward	nd	[RS-EPT-CBR]	[1]
promoter	TSS_2333	2090363	forward	nd	[RS-EPT-CBR]	[1]
promoter	TSS_2334	2090601	forward	nd	[RS-EPT-CBR]	[1]
promoter	TSS_2335	2090638	forward	nd	[RS-EPT-CBR]	[1]
promoter	TSS_2336	2090650	forward	nd	[RS-EPT-CBR]	[1]
promoter	TSS_2337	2090803	forward	nd	[RS-EPT-CBR]	[1]
promoter	TSS_2338	2090809	forward	nd	[RS-EPT-CBR]	[1]
promoter	TSS_2339	2090819	forward	nd	[RS-EPT-CBR]	[1]
promoter	TSS_2340	2091010	forward	nd	[RS-EPT-CBR]	[1]
promoter	TSS_2341	2091072	forward	nd	[RS-EPT-CBR]	[1]
promoter	TSS_2342	2091081	forward	nd	[RS-EPT-CBR]	[1]
promoter	TSS_2343	2091087	forward	nd	[RS-EPT-CBR]	[1]

Evidence
[RS-EPT-CBR] RNA-seq using two enrichment strategies for primary transcripts and consistent biological replicates

Reference(s)
[1] Salgado H, Peralta-Gil M, Gama-Castro S, Santos-Zavaleta A, Muñiz-Rascado L, García-Sotelo JS, Weiss V, Solano-Lira H, Martínez-Flores I, Medina-Rivera A, Salgado-Osorio G, Alquicira-Hernández S, Alquicira-Hernández K, López-Fuentes A, Porrón-Sotelo L, Huerta AM, Bonavides-Martínez C, Balderas-Martínez YI, Pannier L, Olvera M, Labastida A, Jiménez-Jacinto V, Vega-Alvarado L, Del Moral-Chávez V, Hernández-Alvarez A, Morett E, Collado-Vides J., 2012, RegulonDB v8.0: omics data sets, evolutionary conservation, regulatory phrases, cross-validated gold standards and more., Nucleic Acids Res.

Reference(s)