RegulonDB RegulonDB 10.10: Gene Form
   

pheL gene in Escherichia coli K-12 genome


Gene local context to scale (view description)

Gene      
Name: pheL    Texpresso search in the literature
Synonym(s): ECK2595, EG11271, b2598, pheAE
Genome position(nucleotides): 2737599 --> 2737646 Genome Browser
Strand: forward
Sequence: Get nucleotide sequence FastaFormat
GC content %:  
 37.5
External database links:  
ASAP:
 ABE-0008543
ECHOBASE:
 EB1250
ECOLIHUB:
 pheL
OU-MICROARRAY:
 b2598
COLOMBOS: pheL


Product      
Name: phe operon leader peptide
Synonym(s): PheL, leader peptide of chorismate mutase-P-prephenate dehydratase
Sequence: Get amino acid sequence Fasta Format
Cellular location: membrane
Molecular weight: 1.924
Isoelectric point: 9.706
Classification:
Multifun Terms (GenProtEC)  
  1 - metabolism --> 1.5 - biosynthesis of building blocks --> 1.5.1 - amino acids --> 1.5.1.13 - phenylalanine
Gene Ontology Terms (GO)  
cellular_component GO:0016020 - membrane
Note(s): Note(s): ...[more].
Evidence: [IDA] Inferred from direct assay
Reference(s): [1] Gurvich OL., et al., 2003
External database links:  
ECOCYC:
 EG11271-MONOMER
ECOLIWIKI:
 b2598
REFSEQ:
 NP_417089
UNIPROT:
 P0AD72


Operon      
Name: pheLA         
Operon arrangement:
Transcription unit        Promoter
pheLA


RNA cis-regulatory element    
Attenuation: Transcriptional


Elements in the selected gene context region unrelated to any object in RegulonDB      

  Type Name Post Left Post Right Strand Notes Evidence (Confirmed, Strong, Weak) References
  promoter TSS_2937 2737381 forward nd [RS-EPT-CBR] [2]
  promoter TSS_2938 (cluster) 2737413 forward nd [RS-EPT-CBR] [2]
  promoter TSS_2939 2737580 forward nd [RS-EPT-CBR] [2]
  promoter TSS_2940 2737804 forward nd [RS-EPT-CBR] [2]


Evidence    

 [RS-EPT-CBR] RNA-seq using two enrichment strategies for primary transcripts and consistent biological replicates


Reference(s)    

 [1] Gurvich OL., Baranov PV., Zhou J., Hammer AW., Gesteland RF., Atkins JF., 2003, Sequences that direct significant levels of frameshifting are frequent in coding regions of Escherichia coli., EMBO J 22(21):5941-50

 [2] Salgado H, Peralta-Gil M, Gama-Castro S, Santos-Zavaleta A, Muñiz-Rascado L, García-Sotelo JS, Weiss V, Solano-Lira H, Martínez-Flores I, Medina-Rivera A, Salgado-Osorio G, Alquicira-Hernández S, Alquicira-Hernández K, López-Fuentes A, Porrón-Sotelo L, Huerta AM, Bonavides-Martínez C, Balderas-Martínez YI, Pannier L, Olvera M, Labastida A, Jiménez-Jacinto V, Vega-Alvarado L, Del Moral-Chávez V, Hernández-Alvarez A, Morett E, Collado-Vides J., 2012, RegulonDB v8.0: omics data sets, evolutionary conservation, regulatory phrases, cross-validated gold standards and more., Nucleic Acids Res.

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