RegulonDB RegulonDB 10.9: Gene Form
   

waaS gene in Escherichia coli K-12 genome


Gene local context to scale (view description)

waaB waaS waaP waaG TSS_4210 (cluster) TSS_4210 (cluster)

Gene      
Name: waaS    Texpresso search in the literature
Synonym(s): ECK3619, EG11350, b3629, rfaS
Genome position(nucleotides): 3804181 <-- 3805116 Genome Browser
Strand: reverse
Sequence: Get nucleotide sequence FastaFormat
GC content %:  
26.82
External database links:  
ASAP:
ABE-0011864
CGSC:
28949
ECHOBASE:
EB1325
ECOLIHUB:
rfaS
OU-MICROARRAY:
b3629
STRING:
511145.b3629
COLOMBOS: waaS


Product      
Name: lipopolysaccharide core biosynthesis protein WaaS
Synonym(s): RfaS, WaaS
Sequence: Get amino acid sequence Fasta Format
Cellular location: cytosol,inner membrane
Molecular weight: 36.73
Isoelectric point: 9.224
Classification:
Multifun Terms (GenProtEC)  
  1 - metabolism --> 1.6 - biosynthesis of macromolecules (cellular constituents) --> 1.6.3 - lipopolysaccharide --> 1.6.3.2 - core region
  6 - cell structure --> 6.3 - surface antigens (ECA, O antigen of LPS)
Gene Ontology Terms (GO)  
cellular_component GO:0005829 - cytosol
GO:0005886 - plasma membrane
biological_process GO:0009103 - lipopolysaccharide biosynthetic process
GO:0009244 - lipopolysaccharide core region biosynthetic process
Note(s): Note(s): ...[more].
Evidence: [IGI] Inferred from genetic interaction
[IMP] Inferred from mutant phenotype
Reference(s): [1] Klena JD., et al., 1992
[2] Pradel E., et al., 1992
External database links:  
ECOCYC:
EG11350-MONOMER
ECOLIWIKI:
b3629
PRIDE:
P27126
PRODB:
PRO_000023726
REFSEQ:
NP_418086
UNIPROT:
P27126


Operon      
Name: rirA-waaQGPSBOJYZU         
Operon arrangement:
Transcription unit        Promoter
rfaYZ
rfaQGPSBIJYZ-waaU
rirA-rfaQGPSBIJYZ-waaU
rfaZ-waaU


Elements in the selected gene context region unrelated to any object in RegulonDB      

  Type Name Post Left Post Right Strand Notes Evidence (Confirmed, Strong, Weak) References
  promoter TSS_4210 (cluster) 3804751 reverse For this promoter, there
Read more >
[RS-EPT-CBR] [3]


Evidence    

 [RS-EPT-CBR] RNA-seq using two enrichment strategies for primary transcripts and consistent biological replicates



Reference(s)    

 [1] Klena JD., Ashford RS., Schnaitman CA., 1992, Role of Escherichia coli K-12 rfa genes and the rfp gene of Shigella dysenteriae 1 in generation of lipopolysaccharide core heterogeneity and attachment of O antigen., J Bacteriol 174(22):7297-307

 [2] Pradel E., Parker CT., Schnaitman CA., 1992, Structures of the rfaB, rfaI, rfaJ, and rfaS genes of Escherichia coli K-12 and their roles in assembly of the lipopolysaccharide core., J Bacteriol 174(14):4736-45

 [3] Salgado H, Peralta-Gil M, Gama-Castro S, Santos-Zavaleta A, Muñiz-Rascado L, García-Sotelo JS, Weiss V, Solano-Lira H, Martínez-Flores I, Medina-Rivera A, Salgado-Osorio G, Alquicira-Hernández S, Alquicira-Hernández K, López-Fuentes A, Porrón-Sotelo L, Huerta AM, Bonavides-Martínez C, Balderas-Martínez YI, Pannier L, Olvera M, Labastida A, Jiménez-Jacinto V, Vega-Alvarado L, Del Moral-Chávez V, Hernández-Alvarez A, Morett E, Collado-Vides J., 2012, RegulonDB v8.0: omics data sets, evolutionary conservation, regulatory phrases, cross-validated gold standards and more., Nucleic Acids Res.


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