RegulonDB RegulonDB 10.9: Gene Form
   

waaL gene in Escherichia coli K-12 genome


Gene local context to scale (view description)

waaL waaC yibX yibY

Gene      
Name: waaL    Texpresso search in the literature
Synonym(s): ECK3612, EG11424, b3622, rfaL
Genome position(nucleotides): 3796948 --> 3798207 Genome Browser
Strand: forward
Sequence: Get nucleotide sequence FastaFormat
GC content %:  
31.9
External database links:  
ASAP:
ABE-0011849
CGSC:
28438
ECHOBASE:
EB1394
ECOLIHUB:
rfaL
OU-MICROARRAY:
b3622
STRING:
511145.b3622
COLOMBOS: waaL


Product      
Name: O-antigen ligase
Synonym(s): M-antigen ligase, RfaL, WaaL, surface polymer:lipid A-core ligase
Sequence: Get amino acid sequence Fasta Format
Cellular location: inner membrane
Molecular weight: 46.878
Isoelectric point: 9.926
Motif(s):
 
Type Positions Sequence
18 -> 38 SMILEIITYILCFFSMIIAFV
205 -> 224 VLYVLALTQTRATLLLFPII
272 -> 272 D
344 -> 344 A
106 -> 126 YLNTAKIFIFGSFIVFLTLTS

 

Classification:
Multifun Terms (GenProtEC)  
  6 - cell structure --> 6.1 - membrane
  6 - cell structure --> 6.3 - surface antigens (ECA, O antigen of LPS)
Gene Ontology Terms (GO)  
cellular_component GO:0016020 - membrane
GO:0005886 - plasma membrane
GO:0005887 - integral component of plasma membrane
GO:0016021 - integral component of membrane
molecular_function GO:0016757 - transferase activity, transferring glycosyl groups
GO:0016874 - ligase activity
biological_process GO:0009103 - lipopolysaccharide biosynthetic process
GO:0009244 - lipopolysaccharide core region biosynthetic process
Note(s): Note(s): ...[more].
Reference(s): [1] Feldman MF., et al., 1999
External database links:  
DIP:
DIP-10673N
ECOCYC:
EG11424-MONOMER
ECOLIWIKI:
b3622
INTERPRO:
IPR007016
PFAM:
PF04932
PRIDE:
P27243
PRODB:
PRO_000023723
REFSEQ:
NP_418079
UNIPROT:
P27243


Operon      
Name: rfaD-waaFCL         
Operon arrangement:
Transcription unit        Promoter
rfaDFCL
rfaDFCL
rfaDFCL
rfaDFCL


Elements in the selected gene context region unrelated to any object in RegulonDB      

  Type Name Post Left Post Right Strand Notes Evidence (Confirmed, Strong, Weak) References


Reference(s)    

 [1] Feldman MF., Marolda CL., Monteiro MA., Perry MB., Parodi AJ., Valvano MA., 1999, The activity of a putative polyisoprenol-linked sugar translocase (Wzx) involved in Escherichia coli O antigen assembly is independent of the chemical structure of the O repeat., J Biol Chem 274(49):35129-38


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