RegulonDB RegulonDB 10.9: Gene Form
   

waaZ gene in Escherichia coli K-12 genome


Gene local context to scale (view description)

waaU waaZ waaY TSS_4209 TSS_4209 waaUp8 waaUp8 waaUp6 waaUp6 waaUp5 waaUp5 waaUp9 waaUp9

Gene      
Name: waaZ    Texpresso search in the literature
Synonym(s): ECK3614, EG11426, b3624, rfaZ
Genome position(nucleotides): 3799345 <-- 3800196 Genome Browser
Strand: reverse
Sequence: Get nucleotide sequence FastaFormat
GC content %:  
32.51
External database links:  
ASAP:
ABE-0011854
CGSC:
33824
ECHOBASE:
EB1396
ECOLIHUB:
rfaZ
OU-MICROARRAY:
b3624
STRING:
511145.b3624
COLOMBOS: waaZ


Product      
Name: lipopolysaccharide core biosynthesis protein WaaZ
Synonym(s): RfaZ, WaaZ, protein involved in KdoIII attachment during lipopolysaccharide core biosynthesis
Sequence: Get amino acid sequence Fasta Format
Cellular location: cytosol,inner membrane
Molecular weight: 32.92
Isoelectric point: 9.531
Motif(s):
 
Type Positions Sequence
58 -> 58 S

 

Classification:
Multifun Terms (GenProtEC)  
  1 - metabolism --> 1.6 - biosynthesis of macromolecules (cellular constituents) --> 1.6.3 - lipopolysaccharide --> 1.6.3.2 - core region
  6 - cell structure --> 6.3 - surface antigens (ECA, O antigen of LPS)
Gene Ontology Terms (GO)  
cellular_component GO:0005829 - cytosol
GO:0005886 - plasma membrane
biological_process GO:0009103 - lipopolysaccharide biosynthetic process
GO:0009244 - lipopolysaccharide core region biosynthetic process
Note(s): Note(s): ...[more].
External database links:  
CAZY:
GT73
ECOCYC:
EG11426-MONOMER
ECOLIWIKI:
b3624
INTERPRO:
IPR031026
PRIDE:
P27241
PRODB:
PRO_000023728
REFSEQ:
NP_418081
UNIPROT:
P27241


Operon      
Name: rirA-waaQGPSBOJYZU         
Operon arrangement:
Transcription unit        Promoter
rfaYZ
rfaQGPSBIJYZ-waaU
rirA-rfaQGPSBIJYZ-waaU
rfaZ-waaU


Transcriptional Regulation      
Display Regulation             
Activated by: MarA, SoxS


Elements in the selected gene context region unrelated to any object in RegulonDB      

  Type Name Post Left Post Right Strand Notes Evidence (Confirmed, Strong, Weak) References
  promoter waaUp9 3799398 reverse Similarity to the consensus
Read more >
[ICWHO] [1]
  promoter waaUp5 3799424 reverse Similarity to the consensus
Read more >
[ICWHO] [1]
  promoter waaUp6 3799496 reverse Similarity to the consensus
Read more >
[ICWHO] [1]
  promoter waaUp8 3799498 reverse Similarity to the consensus
Read more >
[ICWHO] [1]
  promoter TSS_4209 3800612 reverse nd [RS-EPT-CBR] [2]


Evidence    

 [ICWHO] Inferred computationally without human oversight

 [RS-EPT-CBR] RNA-seq using two enrichment strategies for primary transcripts and consistent biological replicates



Reference(s)    

 [1] Huerta AM., Collado-Vides J., 2003, Sigma70 promoters in Escherichia coli: specific transcription in dense regions of overlapping promoter-like signals., J Mol Biol 333(2):261-78

 [2] Salgado H, Peralta-Gil M, Gama-Castro S, Santos-Zavaleta A, Muñiz-Rascado L, García-Sotelo JS, Weiss V, Solano-Lira H, Martínez-Flores I, Medina-Rivera A, Salgado-Osorio G, Alquicira-Hernández S, Alquicira-Hernández K, López-Fuentes A, Porrón-Sotelo L, Huerta AM, Bonavides-Martínez C, Balderas-Martínez YI, Pannier L, Olvera M, Labastida A, Jiménez-Jacinto V, Vega-Alvarado L, Del Moral-Chávez V, Hernández-Alvarez A, Morett E, Collado-Vides J., 2012, RegulonDB v8.0: omics data sets, evolutionary conservation, regulatory phrases, cross-validated gold standards and more., Nucleic Acids Res.


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