RegulonDB RegulonDB 10.9: Gene Form
   

wzyE gene in Escherichia coli K-12 genome


Gene local context to scale (view description)

wzyE wzxE wecF rffM TSS_4448 TSS_4448 TSS_4447 (cluster) TSS_4447 (cluster) TSS_4446 TSS_4446 TSS_4445 (cluster) TSS_4445 (cluster)

Gene      
Name: wzyE    Texpresso search in the literature
Synonym(s): ECK3786, EG11457, b3793, rffT
Genome position(nucleotides): 3978601 --> 3979953 Genome Browser
Strand: forward
Sequence: Get nucleotide sequence FastaFormat
GC content %:  
52.4
External database links:  
ASAP:
ABE-0012392
CGSC:
33930
ECHOBASE:
EB1426
ECOLIHUB:
wzyE
OU-MICROARRAY:
b3793
STRING:
511145.b3793
COLOMBOS: wzyE


Product      
Name: putative enterobacterial common antigen polymerase
Synonym(s): RffT, WzyE
Sequence: Get amino acid sequence Fasta Format
Cellular location: inner membrane
Molecular weight: 51.517
Isoelectric point: 9.94
Motif(s):
 
Type Positions Sequence
207 -> 227 IIIAFAIFLFIGIIRGWISLW
118 -> 138 VILMGIALVSVGIFFMHNGFL
228 -> 248 MLAAAGVLGIVGMFWLALKRY
37 -> 57 VFFSLLFLLTFFFGFPLTSVL
63 -> 83 VGVAPPEILLQALLSAGCFYA

 

Classification:
Multifun Terms (GenProtEC)  
  1 - metabolism --> 1.6 - biosynthesis of macromolecules (cellular constituents) --> 1.6.4 - enterobacterial common antigen (surface glycolipid)
  6 - cell structure --> 6.1 - membrane
  6 - cell structure --> 6.3 - surface antigens (ECA, O antigen of LPS)
Gene Ontology Terms (GO)  
cellular_component GO:0016020 - membrane
GO:0005886 - plasma membrane
GO:0005887 - integral component of plasma membrane
GO:0016021 - integral component of membrane
biological_process GO:0009246 - enterobacterial common antigen biosynthetic process
Note(s): Note(s): ...[more].
Evidence: [IMP] Inferred from mutant phenotype
Reference(s): [1] Rahman A., et al., 2001
External database links:  
ECOCYC:
FUC4NACTRANS-MONOMER
ECOLIWIKI:
b3793
INTERPRO:
IPR010691
PFAM:
PF06899
PRIDE:
P27835
REFSEQ:
NP_418241
UNIPROT:
P27835


Operon      
Name: rfe-wzzE-wecBC-rffGHC-wecE-wzxE-wecF-wzyE-rffM         
Operon arrangement:
Transcription unit        Promoter
rfe-wzzE-wecBC-rffGHC-wecE-wzxE-wecF-wzyE-rffM


Transcriptional Regulation      
Display Regulation             
Repressed by: NsrR


Elements in the selected gene context region unrelated to any object in RegulonDB      

  Type Name Post Left Post Right Strand Notes Evidence (Confirmed, Strong, Weak) References
  promoter TSS_4445 (cluster) 3977392 forward For this promoter, there
Read more >
[RS-EPT-CBR] [2]
  promoter TSS_4446 3979755 forward nd [RS-EPT-CBR] [2]
  promoter TSS_4447 (cluster) 3979832 forward For this promoter, there
Read more >
[RS-EPT-CBR] [2]
  promoter TSS_4448 3979835 forward nd [RS-EPT-CBR] [2]


Evidence    

 [RS-EPT-CBR] RNA-seq using two enrichment strategies for primary transcripts and consistent biological replicates



Reference(s)    

 [1] Rahman A., Barr K., Rick PD., 2001, Identification of the structural gene for the TDP-Fuc4NAc:lipid II Fuc4NAc transferase involved in synthesis of enterobacterial common antigen in Escherichia coli K-12., J Bacteriol 183(22):6509-16

 [2] Salgado H, Peralta-Gil M, Gama-Castro S, Santos-Zavaleta A, Muñiz-Rascado L, García-Sotelo JS, Weiss V, Solano-Lira H, Martínez-Flores I, Medina-Rivera A, Salgado-Osorio G, Alquicira-Hernández S, Alquicira-Hernández K, López-Fuentes A, Porrón-Sotelo L, Huerta AM, Bonavides-Martínez C, Balderas-Martínez YI, Pannier L, Olvera M, Labastida A, Jiménez-Jacinto V, Vega-Alvarado L, Del Moral-Chávez V, Hernández-Alvarez A, Morett E, Collado-Vides J., 2012, RegulonDB v8.0: omics data sets, evolutionary conservation, regulatory phrases, cross-validated gold standards and more., Nucleic Acids Res.


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