RegulonDB RegulonDB 10.9: Gene Form
   

mltG gene in Escherichia coli K-12 genome


Gene local context to scale (view description)

mltG holB pabC tmk TSS_1420 TSS_1420 TSS_1419 TSS_1419 TSS_1418 TSS_1418

Gene      
Name: mltG    Texpresso search in the literature
Synonym(s): ECK1083, EG11494, b1097, yceG
Genome position(nucleotides): 1154112 --> 1155134 Genome Browser
Strand: forward
Sequence: Get nucleotide sequence FastaFormat
GC content %:  
50.73
External database links:  
ASAP:
ABE-0003712
ECHOBASE:
EB1457
ECOLIHUB:
yceG
OU-MICROARRAY:
b1097
STRING:
511145.b1097
COLOMBOS: mltG


Product      
Name: endolytic murein transglycosylase
Synonym(s): MltG, YceG
Sequence: Get amino acid sequence Fasta Format
Cellular location: periplasmic space,inner membrane
Molecular weight: 38.247
Isoelectric point: 9.926
Motif(s):
 
Type Positions Sequence
1 -> 4 MKKV
5 -> 24 LLIILLLLVVLGIAAGVGVW
25 -> 340 KVRHLADSKLLIKEETIFTLKPGTGRLALGEQLYADKIINRPRVFQWLLRIEPDLSHFKAGTYRFTPQMTVREMLKLLESGKEAQFPLRLVEGMRLSDYLKQLREAPYIKHTLSDDKYATVAQALELENPEWIEGWFWPDTWMYTANTTDVALLKRAHKKMVKAVDSAWEGRADGLPYKDKNQLVTMASIIEKETAVASERDKVASVFINRLRIGMRLQTDPTVIYGMGERYNGKLSRADLETPTAYNTYTITGLPPGAIATPGADSLKAAAHPAKTPYLYFVADGKGGHTFNTNLASHNKSVQDYLKVLKEKNAQ
4 -> 24 VLLIILLLLVVLGIAAGVGVW
218 -> 218 E

 

Classification:
Multifun Terms (GenProtEC)  
  1 - metabolism --> 1.6 - biosynthesis of macromolecules (cellular constituents) --> 1.6.7 - murein (peptidoglycan)
  5 - cell processes --> 5.1 - cell division
Gene Ontology Terms (GO)  
cellular_component GO:0016020 - membrane
GO:0030288 - outer membrane-bounded periplasmic space
GO:0005886 - plasma membrane
GO:0005887 - integral component of plasma membrane
GO:0016021 - integral component of membrane
molecular_function GO:0005515 - protein binding
GO:0016829 - lyase activity
GO:0008933 - lytic transglycosylase activity
GO:0042802 - identical protein binding
GO:0008932 - lytic endotransglycosylase activity
biological_process GO:0000270 - peptidoglycan metabolic process
GO:0000910 - cytokinesis
GO:0009252 - peptidoglycan biosynthetic process
GO:0071555 - cell wall organization
Note(s): Note(s): ...[more].
External database links:  
ECOCYC:
EG11494-MONOMER
ECOLIWIKI:
b1097
INTERPRO:
IPR003770
PANTHER:
PTHR30518
PDB:
2R1F
PFAM:
PF02618
PRIDE:
P28306
REFSEQ:
NP_415615
SMR:
P28306
UNIPROT:
P28306


Operon      
Name: pabC-mltG-tmk-holB-ycfH         
Operon arrangement:
Transcription unit        Promoter
pabC-mltG-tmk-holB-ycfH


Elements in the selected gene context region unrelated to any object in RegulonDB      

  Type Name Post Left Post Right Strand Notes Evidence (Confirmed, Strong, Weak) References
  promoter TSS_1418 1155058 forward nd [RS-EPT-CBR] [1]
  promoter TSS_1419 1156471 forward nd [RS-EPT-CBR] [1]
  promoter TSS_1420 1156478 forward nd [RS-EPT-CBR] [1]


Evidence    

 [RS-EPT-CBR] RNA-seq using two enrichment strategies for primary transcripts and consistent biological replicates



Reference(s)    

 [1] Salgado H, Peralta-Gil M, Gama-Castro S, Santos-Zavaleta A, Muñiz-Rascado L, García-Sotelo JS, Weiss V, Solano-Lira H, Martínez-Flores I, Medina-Rivera A, Salgado-Osorio G, Alquicira-Hernández S, Alquicira-Hernández K, López-Fuentes A, Porrón-Sotelo L, Huerta AM, Bonavides-Martínez C, Balderas-Martínez YI, Pannier L, Olvera M, Labastida A, Jiménez-Jacinto V, Vega-Alvarado L, Del Moral-Chávez V, Hernández-Alvarez A, Morett E, Collado-Vides J., 2012, RegulonDB v8.0: omics data sets, evolutionary conservation, regulatory phrases, cross-validated gold standards and more., Nucleic Acids Res.


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