RegulonDB RegulonDB 11.1: Gene Form
   

sra gene in Escherichia coli K-12 genome


Gene local context to scale (view description)

maeA bdm sra ppGpp terminator srap srap maeAp3 maeAp3 maeAp4 maeAp4 adhPp5 adhPp5

Gene      
Name: sra    Texpresso search in the literature
Synonym(s): ECK1474, EG11508, b1480, rpsV
Genome position(nucleotides): 1555826 <-- 1555963
Strand: reverse
Sequence: Get nucleotide sequence FastaFormat
GC content %:  
 44.2
External database links:  
ASAP:
 ABE-0004935
CGSC:
 32198
ECHOBASE:
 EB1471
ECOLIHUB:
 sra
OU-MICROARRAY:
 b1480
STRING:
 511145.b1480
COLOMBOS: sra


Product      
Name: ribosome-associated protein Sra
Synonym(s): 30S ribosomal subunit protein S22, RpsV, Sra, protein D
Sequence: Get amino acid sequence Fasta Format
Cellular location: cytosol,ribosome
Molecular weight: 5.096
Isoelectric point: 11.696
Motif(s):
 
Type Positions Sequence Comment
1 -> 44 MKSNRQARHILGLDHKISNQRKIVTEGDKSSVVNNPTGRKRPAE

 
Classification:
Multifun Terms (GenProtEC)  
  2 - information transfer --> 2.3 - protein related --> 2.3.2 - translation
  2 - information transfer --> 2.3 - protein related --> 2.3.8 - ribosomal proteins
  6 - cell structure --> 6.6 - ribosomes
Gene Ontology Terms (GO)  
cellular_component GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0005840 - ribosome
molecular_function GO:0003735 - structural constituent of ribosome
GO:0043024 - ribosomal small subunit binding
biological_process GO:0006412 - translation
Note(s): Note(s): ...[more].
Reference(s): [1] Arnold RJ., et al., 1999
[2] van de Waterbeemd M., et al., 2017
External database links:  
ALPHAFOLD:
 P68191
DIP:
 DIP-48175N
ECOCYC:
 EG11508-MONOMER
ECOLIWIKI:
 b1480
INTERPRO:
 IPR012607
PFAM:
 PF08136
PRIDE:
 P68191
PRODB:
 PRO_000023982
REFSEQ:
 NP_415997
UNIPROT:
 P68191


Operon      
Name: bdm-sra         
Operon arrangement:
Transcription unit        Promoter
sra
bdm-sra


Transcriptional Regulation      
Display Regulation             
Activated by: IHF, RcsB, Fis
Repressed by: OmpR


RNA cis-regulatory element    
Attenuation: Translational


Elements in the selected gene context region unrelated to any object in RegulonDB      

  Type Name Post Left Post Right Strand Notes Evidence (Confirmed, Strong, Weak) References
  promoter adhPp5 1553994 reverse nd [COMP-AINF] [3]
  promoter maeAp4 1555727 reverse nd [COMP-AINF] [3]
  promoter maeAp3 1555742 reverse nd [COMP-AINF] [3]


Evidence    

 [COMP-AINF] Inferred computationally without human oversight


Reference(s)    

 [1] Arnold RJ., Reilly JP., 1999, Observation of Escherichia coli ribosomal proteins and their posttranslational modifications by mass spectrometry., Anal Biochem 269(1):105-12

 [2] van de Waterbeemd M., Fort KL., Boll D., Reinhardt-Szyba M., Routh A., Makarov A., Heck AJ., 2017, High-fidelity mass analysis unveils heterogeneity in intact ribosomal particles., Nat Methods 14(3):283-286

 [3] Huerta AM., Collado-Vides J., 2003, Sigma70 promoters in Escherichia coli: specific transcription in dense regions of overlapping promoter-like signals., J Mol Biol 333(2):261-78

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