RegulonDB

RegulonDB RegulonDB 10.9: Gene Form

kch gene in Escherichia coli K-12 genome

Gene local context to scale (view description)

Gene
Name:	kch
Synonym(s):	ECK1244, EG11606, b1250
Genome position(nucleotides):	1309016 <-- 1310269 Genome Browser
Strand:	reverse
Sequence:	Get nucleotide sequence FastaFormat
GC content %:	42.34
External database links:

ASAP:	ABE-0004189
CGSC:	35309
ECHOBASE:	EB1563
ECOLIHUB:	kch
OU-MICROARRAY:	b1250
STRING:	511145.b1250
COLOMBOS:	kch

Product

Name:

K⁺ channel Kch

Synonym(s):

Kch

Sequence:

Get amino acid sequence Fasta Format

Cellular location:

inner membrane

Molecular weight:

46.063

Isoelectric point:

6.59

Motif(s):

Type	Positions	Sequence
	136 -> 153	AAAGTIFAFISFTTLLFY
	406 -> 406	E
	414 -> 414	S
	415 -> 415	A
	111 -> 127	KFSIGFCIFTLVFLLIL

Type	Positions	Sequence
	136 -> 153	AAAGTIFAFISFTTLLFY
	406 -> 406	E
	414 -> 414	S
	415 -> 415	A
	111 -> 127	KFSIGFCIFTLVFLLIL
	185 -> 190	TVGYGD
	200 -> 220	LFTISVIISGITVFATSMTSI
	13 -> 13	N
	61 -> 83	LLANAPLFMLGVFLVLNSIGLLF
	114 -> 127	IGFCIFTLVFLLIL
	411 -> 411	S
	5 -> 5	A
	22 -> 41	ILALAVFLNGLLIFKTIYGM
	141 -> 160	IFAFISFTTLLFYSTYGALY
	150 -> 221	LLFYSTYGALYLSEGFNPRIESLMTAFYFSIETMSTVGYGDIVPVSESARLFTISVIISGITVFATSMTSIF
	223 -> 223	P
	246 -> 365	FIVCGHSILAINTILQLNQRGQNVTVISNLPEDDIKQLEQRLGDNADVIPGDSNDSSVLKKAGIDRCRAILALSDNDADNAFVVLSAKDMSSDVKTVLAVSDSKNLNKIKMVHPDIILSP
	87 -> 104	LAWAISIILLLIALIYTL
	90 -> 104	AISIILLLIALIYTL
	245 -> 371	HFIVCGHSILAINTILQLNQRGQNVTVISNLPEDDIKQLEQRLGDNADVIPGDSNDSSVLKKAGIDRCRAILALSDNDADNAFVVLSAKDMSSDVKTVLAVSDSKNLNKIKMVHPDIILSPQLFGSE
	405 -> 405	L
	64 -> 83	NAPLFMLGVFLVLNSIGLLF

Classification:

Multifun Terms (GenProtEC)
		4 - transport --> 4.1 - Channel-type Transporters --> 4.1.A - alpha-type channels
		6 - cell structure --> 6.1 - membrane
Gene Ontology Terms (GO)
	cellular_component	GO:0016020 - membrane GO:0005886 - plasma membrane GO:0032991 - protein-containing complex GO:0016021 - integral component of membrane
	molecular_function	GO:0042802 - identical protein binding
	biological_process	GO:0006811 - ion transport GO:0006813 - potassium ion transport

Note(s):

Note(s): ...[more].

External database links:

DIP:

ECOCYC:

ECOLIWIKI:

INTERPRO:

INTERPRO:

INTERPRO:

MODBASE:

PDB:

PFAM:

PFAM:

PRIDE:

PROSITE:

REFSEQ:

SMR:

UNIPROT:

Operon

Name:

kch

Operon arrangement:

Transcription unit	Promoter
kch

RNA cis-regulatory element

Attenuation:	Transcriptional

Elements in the selected gene context region unrelated to any object in RegulonDB

	Type	Name	Post Left	Post Right	Strand	Notes	Evidence (Confirmed, Strong, Weak)	References
	promoter	kchp	1310523		reverse	We assigned a putative transcription start site to this promoter based on the observation that the majority of the σ⁵⁴-dependent promoters, whose transcription start sites were determined experimentally, present a distance of 11 nucleotides between the transcription start site and the -12 box Barrios H,1999. Read more >	[AIPP], [ICWHO]	[1], [2]

Evidence
[AIPP] Automated inference of promoter position
[ICWHO] Inferred computationally without human oversight

Reference(s)
[1] Huerta AM., Collado-Vides J., 2003, Sigma70 promoters in Escherichia coli: specific transcription in dense regions of overlapping promoter-like signals., J Mol Biol 333(2):261-78
[2] Reitzer L., Schneider BL., 2001, Metabolic context and possible physiological themes of sigma(54)-dependent genes in Escherichia coli., Microbiol Mol Biol Rev 65(3):422-44, table of contents

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