RegulonDB RegulonDB 10.9: Gene Form
   

setC gene in Escherichia coli K-12 genome


Gene local context to scale (view description)

setC yicL yicT selC yicU terminator anti-terminator anti-anti-terminator terminator TSS_4246 TSS_4246 setCp12 setCp12 setCp13 setCp13 setCp10 setCp10 setCp14 setCp14 yicJp yicJp

Gene      
Name: setC    Texpresso search in the literature
Synonym(s): ECK3649, EG11687, b3659, yicK
Genome position(nucleotides): 3836953 --> 3838137 Genome Browser
Strand: forward
Sequence: Get nucleotide sequence FastaFormat
GC content %:  
46.08
External database links:  
ASAP:
ABE-0011959
ECHOBASE:
EB1638
ECOLIHUB:
setC
OU-MICROARRAY:
b3659
STRING:
511145.b3659
COLOMBOS: setC


Product      
Name: putative arabinose exporter
Synonym(s): SetC, YicK, YicK MFS Transporter
Sequence: Get amino acid sequence Fasta Format
Cellular location: inner membrane
Molecular weight: 43.493
Isoelectric point: 8.375
Motif(s):
 
Type Positions Sequence
11 -> 31 ILDLTAAAFLLVAFLTGIAGA
105 -> 125 FILLSTGVLLSSFASTANPQM
50 -> 70 IMVGFFFTGSAIMGILVSQFL
151 -> 171 ISLAWVIGPPLAYELAMGFSF
254 -> 274 LTGEMIGIAAGLEIPMMLIAG

 

Classification:
Multifun Terms (GenProtEC)  
  4 - transport --> 4.2 - Electrochemical potential driven transporters --> 4.2.A - Porters (Uni-, Sym- and Antiporters)
  6 - cell structure --> 6.1 - membrane
Gene Ontology Terms (GO)  
cellular_component GO:0016020 - membrane
GO:0005886 - plasma membrane
GO:0016021 - integral component of membrane
molecular_function GO:0005351 - carbohydrate:proton symporter activity
GO:0022857 - transmembrane transporter activity
biological_process GO:0008643 - carbohydrate transport
GO:0055085 - transmembrane transport
GO:0015767 - lactose transport
GO:0034219 - carbohydrate transmembrane transport
GO:1902600 - proton transmembrane transport
GO:0036448 - cellular response to glucose-phosphate stress
GO:1904659 - glucose transmembrane transport
Note(s): Note(s): ...[more].
External database links:  
ECOCYC:
B3659-MONOMER
ECOLIWIKI:
b3659
INTERPRO:
IPR011701
INTERPRO:
IPR036259
INTERPRO:
IPR020846
INTERPRO:
IPR004750
MODBASE:
P31436
PANTHER:
PTHR23535:SF2
PFAM:
PF07690
PRIDE:
P31436
PRODB:
PRO_000023938
PROSITE:
PS50850
REFSEQ:
NP_418115
UNIPROT:
P31436


Operon      
Name: setC         
Operon arrangement:
Transcription unit        Promoter
setC


Elements in the selected gene context region unrelated to any object in RegulonDB      

  Type Name Post Left Post Right Strand Notes Evidence (Confirmed, Strong, Weak) References
  promoter setCp14 3836744 forward Similarity to the consensus
Read more >
[ICWHO] [1]
  promoter setCp10 3836768 forward Similarity to the consensus
Read more >
[ICWHO] [1]
  promoter setCp13 3836838 forward Similarity to the consensus
Read more >
[ICWHO] [1]
  promoter setCp12 3836877 forward Similarity to the consensus
Read more >
[ICWHO] [1]
  promoter TSS_4246 3838644 forward nd [RS-EPT-CBR] [2]


Evidence    

 [ICWHO] Inferred computationally without human oversight

 [RS-EPT-CBR] RNA-seq using two enrichment strategies for primary transcripts and consistent biological replicates



Reference(s)    

 [1] Huerta AM., Collado-Vides J., 2003, Sigma70 promoters in Escherichia coli: specific transcription in dense regions of overlapping promoter-like signals., J Mol Biol 333(2):261-78

 [2] Salgado H, Peralta-Gil M, Gama-Castro S, Santos-Zavaleta A, Muñiz-Rascado L, García-Sotelo JS, Weiss V, Solano-Lira H, Martínez-Flores I, Medina-Rivera A, Salgado-Osorio G, Alquicira-Hernández S, Alquicira-Hernández K, López-Fuentes A, Porrón-Sotelo L, Huerta AM, Bonavides-Martínez C, Balderas-Martínez YI, Pannier L, Olvera M, Labastida A, Jiménez-Jacinto V, Vega-Alvarado L, Del Moral-Chávez V, Hernández-Alvarez A, Morett E, Collado-Vides J., 2012, RegulonDB v8.0: omics data sets, evolutionary conservation, regulatory phrases, cross-validated gold standards and more., Nucleic Acids Res.


RegulonDB