RegulonDB RegulonDB 11.1: Gene Form
   

puuB gene in Escherichia coli K-12 genome


Gene local context to scale (view description)

puuC puuB puuE Spot 42

Gene      
Name: puuB    Texpresso search in the literature
Synonym(s): ECK1296, EG11822, b1301, ordL, ycjA
Genome position(nucleotides): 1364232 --> 1365512
Strand: forward
Sequence: Get nucleotide sequence FastaFormat
GC content %:  
 58.24
External database links:  
ASAP:
 ABE-0004378
ECHOBASE:
 EB1769
ECOLIHUB:
 puuB
OU-MICROARRAY:
 b1301
STRING:
 511145.b1301
COLOMBOS: puuB


Product      
Name: γ-glutamylputrescine oxidase
Synonym(s): OrdL, PuuB, YcjA
Sequence: Get amino acid sequence Fasta Format
Cellular location: cytosol
Molecular weight: 47.17
Isoelectric point: 6.781
Motif(s):
 
Type Positions Sequence Comment
29 -> 381 DVCVVGGGYTGLSSALHLAEAGFDVVVLEASRIGFGASGRNGGQLVNSYSRDIDVIEKSYGMDTARMLGSMMFEGGEIIRERIKRYQIDCDYRPGGLFVAMNDKQLATLEEQKENWERYGNKQLELLDANAIRREVASDRYTGALLDHSGGHIHPLNLAIGEADAIRLNGGRVYELSAVTQIQHTTPAVVRTAKGQVTAKYVIVAGNAYLGDKVEPELAKRSMPCGTQVITTERLSEDLARSLIPKNYCVEDCNYLLDYYRLTADNRLLYGGGVVYGARDPDDVERLVVPKLLKTFPQLKGVKIDYRWTGNFLLTLSRMPQFGRLDTNIYYMQGYSGHGVTCTHLAGRLIAEL

 
Classification:
Multifun Terms (GenProtEC)  
  1 - metabolism --> 1.1 - carbon utilization --> 1.1.4 - amines
Gene Ontology Terms (GO)  
cellular_component GO:0005737 - cytoplasm
GO:0005829 - cytosol
molecular_function GO:0016491 - oxidoreductase activity
biological_process GO:0009447 - putrescine catabolic process
Note(s): Note(s): ...[more].
Evidence: [EXP] Inferred from experiment
Reference(s): [1] Kurihara S., et al., 2005
External database links:  
ALPHAFOLD:
 P37906
ECOCYC:
 EG11822-MONOMER
ECOLIWIKI:
 b1301
INTERPRO:
 IPR006076
INTERPRO:
 IPR036188
MODBASE:
 P37906
PFAM:
 PF01266
PRIDE:
 P37906
PRODB:
 PRO_000023650
REFSEQ:
 NP_415817
UNIPROT:
 P37906


Operon      
Name: puuDRCBE         
Operon arrangement:
Transcription unit        Promoter
puuDRCBE
puuCBE


Transcriptional Regulation      
Display Regulation             
Repressed by: CRP, PuuR, ArcA


Elements in the selected gene context region unrelated to any object in RegulonDB      

  Type Name Post Left Post Right Strand Notes Evidence (Confirmed, Strong, Weak) References


Reference(s)    

 [1] Kurihara S., Oda S., Kato K., Kim HG., Koyanagi T., Kumagai H., Suzuki H., 2005, A novel putrescine utilization pathway involves gamma-glutamylated intermediates of Escherichia coli K-12., J Biol Chem 280(6):4602-8

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