RegulonDB RegulonDB 11.1: Gene Form
   

yihU gene in Escherichia coli K-12 genome


Gene local context to scale (view description)

yihU yihV yihT CRP CsqR yihVp1 yihVp1 yihUp5 yihUp5 yihVp3 yihVp3 yihUp4 yihUp4 yihUp3 yihUp3 yihUp2 yihUp2 yihUp1 yihUp1 yihVp6 yihVp6

Gene      
Name: yihU    Texpresso search in the literature
Synonym(s): ECK3875, EG11847, b3882, squU
Genome position(nucleotides): 4072675 <-- 4073571
Strand: reverse
Sequence: Get nucleotide sequence FastaFormat
GC content %:  
 55.3
External database links:  
ASAP:
 ABE-0012678
ECHOBASE:
 EB1793
ECOLIHUB:
 yihU
OU-MICROARRAY:
 b3882
STRING:
 511145.b3882
COLOMBOS: yihU


Product      
Name: 3-sulfolactaldehyde reductase
Synonym(s): SquU, YihU
Sequence: Get amino acid sequence Fasta Format
Cellular location: cytosol
Molecular weight: 31.158
Isoelectric point: 6.237
Motif(s):
 
Type Positions Sequence Comment
4 -> 160 IAFIGLGQMGSPMASNLLQQGHQLRVFDVNAEAVRHLVDKGATPAANPAQAAKDAEFIITMLPNGDLVRNVLFGENGVCEGLSTDALVIDMSTIHPLQTDKLIADMQAKGFSMMDVPVGRTSANAITGTLLLLAGGTAEQVERATPILMAMGSELIN
5 -> 19 AFIGLGQMGSPMASN UniProt: NAD.
165 -> 284 GMGIRVKLINNYMSIALNALSAEAAVLCEALNLPFDVAVKVMSGTAAGKGHFTTSWPNKVLSGDLSPAFMIDLAHKDLGIALDVANQLHVPMPLGAASREVYSQARAAGRGRQDWSAILE

 
Classification:
Multifun Terms (GenProtEC)  
  1 - metabolism --> 1.1 - carbon utilization --> 1.1.1 - carbon compounds
  5 - cell processes --> 5.6 - protection --> 5.6.2 - detoxification
Gene Ontology Terms (GO)  
cellular_component GO:0005829 - cytosol
GO:0032991 - protein-containing complex
molecular_function GO:0016491 - oxidoreductase activity
GO:0016616 - oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
GO:0042802 - identical protein binding
GO:0050661 - NADP binding
GO:0051287 - NAD binding
GO:0047577 - 4-hydroxybutyrate dehydrogenase activity
GO:0061596 - 3-sulfolactaldehyde reductase activity
biological_process GO:0009407 - toxin catabolic process
GO:0051289 - protein homotetramerization
GO:1902777 - 6-sulfoquinovose(1-) catabolic process
GO:0061720 - 6-sulfoquinovose(1-) catabolic process to glycerone phosphate and 3-sulfolactaldehyde
External database links:  
ALPHAFOLD:
 P0A9V8
DIP:
 DIP-48142N
ECOCYC:
 EG11847-MONOMER
ECOLIWIKI:
 b3882
INTERPRO:
 IPR006115
INTERPRO:
 IPR013328
INTERPRO:
 IPR029154
INTERPRO:
 IPR030876
INTERPRO:
 IPR036291
INTERPRO:
 IPR002204
INTERPRO:
 IPR015815
INTERPRO:
 IPR008927
MODBASE:
 P0A9V8
PDB:
 6SMZ
PDB:
 6SM7
PDB:
 6SMY
PFAM:
 PF14833
PFAM:
 PF03446
PRIDE:
 P0A9V8
PROSITE:
 PS00895
REFSEQ:
 NP_418318
SMR:
 P0A9V8
UNIPROT:
 P0A9V8


Operon      
Name: yihUTS         
Operon arrangement:
Transcription unit        Promoter
yihUTS
yihUTS
yihUTS
yihUTS
yihUTS


Transcriptional Regulation      
Display Regulation             
Repressed by: CsqR


Elements in the selected gene context region unrelated to any object in RegulonDB      

  Type Name Post Left Post Right Strand Notes Evidence (Confirmed, Strong, Weak) References
  promoter yihVp6 4073532 forward nd [COMP-AINF] [1]
  promoter yihVp3 4073661 forward nd [COMP-AINF] [1]


Evidence    

 [COMP-AINF] Inferred computationally without human oversight


Reference(s)    

 [1] Huerta AM., Collado-Vides J., 2003, Sigma70 promoters in Escherichia coli: specific transcription in dense regions of overlapping promoter-like signals., J Mol Biol 333(2):261-78

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